L-Ergothioneine

L-ERGOTHIONEINE 99% SAUNIA E HPLC
Antioxidant Premium mo Nutraceutical & Cosmeceutical Applications

1. Va'aiga lautele o oloa

L-Ergothioneine(ERT) ose amino acid e maua mai i le sulfur e maua mai i le fa'afefeteina o microbial, e maua muamua i totonu o pulou e pei oleTricholoma matsutakemaHericium erinaceus. O la matou oloa o se paʻu tioata maualuga (≥99% e le HPLC) faʻatasi ma le CAS Numera 497-30-3, faʻamaonia e ala i suʻesuʻega chromatographic malosi. O loʻo faʻaalia ai le faʻamautu tulaga ese i le pH 4.0-6.0 faʻapipiʻi, faʻapitoa mo suauʻu tausiga paʻu, lotions, ma faʻaopoopoga tuʻu.

Vaega Autu:

• Mama: ≥99% (HPLC-faʻamaonia, faʻapitoa COA tuʻuina atu)
• Fuafuaga mole: C₉H₁₅N₃O₂S | Molecular Weight: 229.3 g/mol
• Solubility: 125 mg/mL ile vai (fesoasoani i le ultrasoni)
• Fa'ailoga: Non-GMO, Allergen-Free, Vegan-Friendly

2. Fa'atonuga Tulaga Lelei & Fa'atonu HPLC

O la matou au'ili'ili fa'agasologa o lo'o fa'atutusa ma fa'ata'ita'iga a tupulaga:

• Sauniuniga Fa'ata'ita'iga: 1 mL fa'aleaganu'u fa'aputuina i le 94°C mo le 10 min, vortexed (1600 rpm/30 min), centrifuged (10,000×g/5 min), ma teu i le -20°C pe a mana'omia .
• HPLC System: Dionex Ultimate 3000 ma Chromeleon software.
• Koluma: Cortecs UPLC T3 (2.1 × 150 mm, 1.6 μm vaega, 120 Å pore lapoa) .
• Fa'asagaga Feavea'i: Fa'asolo malie mai le 0.1% formic acid i le 70% acetonitrile/0.1% formic acid, tafe 0.3 mL/min.
• Su'esu'ega: Su'e le UV ile 254 nm, LOQ 0.15 mmol/L .

Fua Fa'amaonia:

• Linearity: 0.3–10 mmol/L (R² >0.99)
• Sa'o: ≤6% RSD (intra-/inter-assay)
• Toe faʻaleleia: ~ 100% saʻo

3. Soifua Maloloina Fa'amanuiaga & Fa'aoga

3.1 Fa'aaogāga Nutraceutical

• Puipuiga o le Mitochondrial: Faʻaitiitia le faʻamaʻi faʻamaʻi e ala i le faʻafefeina o faʻamaʻi hydroxyl (IC₅₀: 2.5 μM) ma superoxide anion.
• Lagolago Telomere: Fa'atuai le fa'apu'upu'u telomere e feso'ota'i ma tausaga i vitro .
• Fuafuaga: O su'esu'ega fa'afoma'i ua fautua mai ole 5-20 mg/aso e si'itia ai le maualuga ole plasma ERT.

Oloa Fautuaina:

• Capsules: 100 μg–5 mg i le tautua (fa'ata'ita'iga, LifeExtension's Essential Youth) .
• Synergistic Blends: Faʻatasi ma ferulic acid mo le faʻaleleia atili o le bioavailability.

3.2 Fa'aaogāga Fa'afoma'i

• Anti-Aging: Faʻasaʻo le tyrosinase (40% faʻaititia i le 0.5% faʻatonuga) ma puipuia le elastin mai le faʻaleagaina o le UV.
• Fa'atonuga ta'iala:
  • pH: 4.0–6.0 (mautu lelei)
  • Fa'atonuga: 0.5-2.0% i serums / lotions
  • Fegalegaleai: Mausali ma vaitamini C, hyaluronic acid, ma peptides.

4. Fa'amatalaga Fa'apitoa

5. Saogalemu & Tulafono Fa'atonutonu

• Fa'amatalaga Saogalemu: LD₅₀ >2000 mg/kg (tuu, isumu); leai ni aafiaga leaga i tofotofoga faaletagata .
• Tusipasi: EU Novel Food Approval (Ergoneine®), FDA GRAS .
• Taulimaina: Fa'aaoga masini manava fa'amaonia e le NIOSH ma totigilima e fa'a'ese'ese vaila'au a'o fa'agaioiina falegaosimea.

6. Global Supply & Packaging

• Filifiliga Fa'apipi'i: 1 kilokalama, 10 kilokalama, 1000 kilokalama (pepa pepa alumini ma mea fa'amama) .
• Taimi Ta'ita'i: 3-5 aso pisinisi (fa'asalalau fa'avaomalo e ala i le DHL/FedEx) .
• Maketi Auauna: ISA, EU, Ausetalia, Iapani, Pasila .

7. Upu Autu

• upu autu: “L-Ergothioneine 99%HPLC", "Natural Antioxidant Supplier", "Ergothioneine mo Skincare".
• Fa'aaofia CAS 497-30-3, talosaga mama, ma aiaiga talosaga.