Sialic acid (SA), nesainzi inozivikanwa se "N-acetylneuraminic acid," inongoitika carbohydrate.Yakanga yakaparadzaniswa kubva kune submandibular gland mucin, saka zita racho.Sialic acid inowanzovapo nenzira ye oligosaccharides, glycolipids kana glycoproteins.Mumuviri wemunhu, uropi hune yakanyanya sialic acid yemukati.Iyo sialic acid yemukati mune grey nyaya ndeye 15 nguva yenhengo dzemukati senge chiropa nemapapu.Chikafu chikuru chesialic acid mukaka wezamu, unowanikwawo mumukaka, mazai uye chizi.
Mumushonga, glycolipids ine sialic acid inonzi gangliosides, iyo inoita basa rakakosha mukugadzirwa uye kukura kwehuropi uye tsinga system.Panguva imwecheteyo, zvidzidzo zvemhuka zvakaratidza kuti kuderedzwa kwemazinga e ganglioside kunobatanidzwa nekutanga kushaya zvokudya zvinovaka muviri uye kuderedza kukwanisa kudzidza, asi kuwedzera ne sialic acid kunogona kuvandudza maitiro ekudzidza mhuka.Kupiwa kwakakwana kweasilic acid kunogona kunyanya kukosha pakukura kwehuropi muvana vane huremu hushoma.Mushure mekunge mwana azvarwa, iyo sialic acid mumukaka wezamu yakakosha kuti ive nechokwadi chekukura kwavo kwese.Ongororo dzakaratidza kuti sialic acid mazinga mumadzimai mushure mekusununguka anoderera nekufamba kwenguva.Naizvozvo, kuenderera kunotora huwandu hwakakwana hweasilic acid panguva yekuzvitakura uye mushure mekuzvitakura kunogona kubatsira kuchengetedza sialic acid mazinga mumuviri.Uyezve, zvinyorwa zvesialic acid zvakabatanidzwawo zvakanyanya nezviri muDHA, zvichiratidza kuti inonyanya kuve yakabatana nehuropi hwekugadzirisa uye uropi hunoita basa mucheche, zvose zvingave zvinobatsira pakukura kwehuropi.
Zvidzidzo zvakaratidza kuti nguva yegoridhe yekukura kwehuropi hwemunhu iri pakati pemakore maviri kusvika maviri ezera.Iyi nhanho inguva yakaoma yehuropi masero ekugadzirisa nhamba, kuwedzera vhoriyamu, kushanda kwakakwana, uye neural network kuumbwa.Naizvozvo, vanaamai vakangwara vanozonyatso teerera kune kudyiwa kwakakwana kweasilic acid panguva yekuzvitakura.Mushure mokunge mwana aberekwa, mukaka wezamu inzira inobatsira yekuwedzera sialic acid kumwana, nokuti inenge 0.3-1.5 mg ye sialic acid pa millilita yemukaka wezamu.Muchokwadi, mhuka dzese dzinoyamwisa, kusanganisira vanhu, vanokwanisa kugadzira sialic acid kubva pachiropa vari voga.Zvisinei, kukura kwechiropa kwevana vachangoberekwa hakusati kwakura, uye kudiwa kwekukurumidza kukura nekukura kwehuropi kunogona kuderedza kuumbwa kweasilic acid, kunyanya kune vacheche vasati vasvika.Naizvozvo, sialic acid mumukaka wezamu yakakosha pakuita kuti mwana awedzere kukura uye kukura.
Vatsvakurudzi vekuAustralia vakaona kuti vacheche vanoyamwisa vane huwandu hwakanyanya hwesialic acid mu frontal cortex pane vacheche vanoyamwisa.Izvi zvinogona kukurudzira kuumbwa kwe synapses, kubatsira ndangariro yemwana kuumba hwaro hwakasimba hwemaitiro, uye kusimbisa kukura kwetsinga.
| Product name | N-Acetylneuraminic acid powder |
| Rimwe Zita | N-Acetylneuraminic acid, N-Acetyl-D-neuraminic acid, 5-Acetamido-3,5-dideoxy-D-glycerol-D-galactonulosonic acid o-Sialic acid Galactononulosonic acid Lactaminic acid NANA N-Acetylsialic acid |
| Nhamba yeCAS: | 131-48-6 |
| Content | 98% neHPLC |
| Chitarisiko | White Powder |
| Molecular formula | C11H19NO9 |
| Molecular Weight | 309.27 |
| Mvura-inonyungudika Mano | 100% mvura inonyungudika |
| Source | 100% zvisikwa zvine Fermentation process |
| Bulk package | 25kg / chigubhu |
Chii chinonzi Sialic acid
Sialic Acidiboka rezvinobva kune neuraminic acid (N- kana O-inotsiva derivatives neuraminic acid).Kazhinji muchimiro che oligosaccharides, glycolipids kana glycoproteins.
Sialic Acidndiro zvakare zita renhengo yeboka iri inonyanya kuzivikanwa - N-acetylneuraminic acid (Neu5Ac kana NANA).
Sialic acid mhuri
Iyo yave ichizivikanwa kune vangangoita makumi mashanu nhengo, zvese zvinobva kune zvakashata kupomerwa 9-carbon shuga neuraminic acid.
N-acetylneuraminic acid (Neu5Ac), N-glycolylneuraminic
asidhi (Neu5Gc) uye deaminoneuraminic acid (KDN) ndiwo musimboti wayo monomer.
N-acetylneuraminic acid ndiyo chete mhando yeSialic Acid mumuviri wedu.
Sialic Acid uye dendere reShiri
Nemhaka yokuti Sialic acid yakapfuma mudendere reshiri, inonziwo bird's nest acid, inova chiratidzo chinokosha chekugadzirisa dendere reshiri.
Sialic Acid ndiyo inonyanya kudya zvinovaka mudendere reShiri, yakatenderedza 3% -15% nehuremu.
Pakati pezvikafu zvese zvinozivikanwa, dendere reShiri rine yakakwira yeSialid asidhi, yakapetwa ka50 kupfuura zvimwe zvekudya.
1g dendere reShiri rakaenzana nemazai makumi mana kana tikawana huwandu hwakafanana hweSialic Acid.
Sialic Acid chikafu masosi
Kazhinji, zvirimwa hazvina Sialic acid.Iyo inotungamira kupihwa kweSialic acid mukaka wemunhu, nyama, zai, uye chizi.
Zviri mukati meiyo yakazara Sialic asidhi mune zvakajairwa chikafu (µg/g kana µg/ml).
| Sample yekudya mbishi | Neu5Ac | Neu5Gc | Total | Neu5Gc, % yezvese |
| Nyama yemombe | 63.03 | 25.00 | 88.03 | 28.40 |
| Mafuta emombe | 178.54 | 85.17 | 263.71 | 32.30 |
| Nyama yenguruve | 187.39 | 67.49 | 254.88 | 26.48 |
| Gwayana | 172.33 | 97.27 | 269.60 | 36.08 |
| Ham | 134.76 | 44.35 | 179.11 | 24.76 |
| Huku | 162.86 | 162.86 | ||
| Dhadha | 200.63 | 200.63 | ||
| Zai jena | 390.67 | 390.67 | ||
| Zai yolk | 682.04 | 682.04 | ||
| Salmon | 104.43 | 104.43 | ||
| Cod | 171.63 | 171.63 | ||
| Tuna | 77.98 | 77.98 | ||
| Mukaka (2% Mafuta 3% Pr) | 93.75 | 3.51 | 97.26 | 3.61 |
| Ruta | 206.87 | 206.87 | ||
| Cheese | 231.10 | 17.01 | 248.11 | 6.86 |
| Mukaka wemunhu | 602.55 | 602.55 |
Isu tinogona kuona kuti iyo Sialic acid mumukaka weMunhu yakakwira, inova ndiyo yakakosha yekukura kwehuropi hwemwana.
Asi Sialic Acid yemukati yakasiyana muNguva dzakasiyana Mukaka wemunhu
Mukaka wemukaka colostrum 1300 +/- 322 mg/l
Mazuva gumi gare gare 983 +/- 455 mg/l
Preterm mucheche mukaka upfu 197 +/- 31 mg/l
Yakagadziriswa mukaka mafomula 190 +/- 31 mg/l
Zvikamu zvakagadziridzwa mukaka mafomula 100 +/- 33 mg/l
Kutevera mukaka mafomula 100 +/- 33 mg/l
Soy-based milk formulas 34 +/- 9 mg/l
Kuenzaniswa nemukaka wezamu, Hupfu hweMucheche hune 20% Sialic acid kubva mumukaka weMunhu, nepo mwana achingowana 25% Sialic acid kubva mumukaka wezamu.
Kumwana asati azvarwa, Sialic acid yakakosha kudarika mwana ane hutano mukukura kweBrain.
Sialic Acid Kudzidza paMukaka poda
"Zvigumisiro zvakaratidza kuti brain sialic acid yemukati inoita basa rakakosha pakuona maitiro.Rimwe boka rakaona kuvandudza kudzidza nemahara sialic acid kurapwa mumakonzo. "
Ongororo yeCAB: Maonero mune Zvekurima, Veterinary Sayenzi, Zvokudya, uye Zvakasikwa
Zviwanikwa 2006 1, Nha. 018, Ko sialic acid mumukaka chikafu chehuropi?, Bing Wang
"Mhedziso ndeyeKumusoro kwehuropi ganglioside uye glycoprotein sialic acid yakawanda muvacheche vanopihwa mukaka wevanhu inoratidza kuwedzera synaptogenesis uye mutsauko mukuvandudza neurodevelopment."
Am J Clin Nutr 2003;78:1024–9.Yakadhindwa muUSA.© 2003 American Society for Clinical Nutrition，Brain ganglioside, uye glycoprotein sialic acid inoyamwisa kana ichienzaniswa nevacheche vanoyamwisa, Bing Wang.
"Neural cell membranes ine 20 times more sialic acid pane mamwe marudzi e membranes, zvichiratidza kuti sialic acid ine basa rakajeka mukuumbwa kweneural."
IEuropean Journal yeClinical Nutrition, (2003) 57, 1351-1369, Basa uye kugona kweasilic acid mukudya kwevanhu, Bing Wang.
N-Acetylneuraminic acid Kushandiswa
Mukaka Powder
Parizvino, Hupfu hwemukaka hwaamai Vanoyamwisa huzhinji, Hupfu hweVacheche, uye Zvokudya zvinovaka muviri zvine Sialic Acid paMusika.
KwaMai Vanoyamwisa
Yemucheche Mukaka hupfu 0-12 mwedzi
For Healthcare chigadzirwa
Zvechinwiwa
Sezvo Sialic acid ine yakanaka-inonyungudika mumvura, makambani mazhinji ari kuyedza kugadzira Sialic acid zvinwiwa zvehutano hweBrain kana kuwedzera mune zvigadzirwa zvemukaka.
N-Acetylneuraminic acid Kuchengetedza
N-Acetylneuraminic acid yakachengeteka zvakanyanya.Parizvino, hapana nhau dzakaipa dzakataurwa nezveSialic acid.
Hurumende dzeUSA, China, neEU dzinotendera Sialic acid kuti ishandiswe muChikafu uye Hutano hwekuchengeta zvigadzirwa.
USA
Muna 2015, N-Acetyl-D-neuraminic acid (Sialic acid) yakatemerwa Kazhinji Kuzivikanwa SeYakachengeteka (GRAS)
China
Muna 2017, Hurumende yeChina yakabvumidza N-Acetylneuraminic acid seNyowani Yechikafu Ingredient.
EU
Kuchengetedzwa kweiyo synthetic N-acetyl-d-neuraminic acid sechikafu chitsva pasi peMutemo (EC) No 258/97
Musi wa16 Gumiguru 2015, zita renherera (EU/3/12/972) rakapihwa neEuropean Commission kuUltragenyx UK Limited, United Kingdom, yesialic acid (inozivikanwawo seaceneuramic acid) yekurapa GNE myopathy.
Maonero eSainzi pamusoro pekusimbiswa kwezvichemo zvehutano zvine chekuita nesialic acid uye kudzidza uye ndangariro (ID 1594) zvinoenderana neChinyorwa 13 (1) cheMutemo (EC) No 1924/2006.
Dosage
CFDA inokurudzira 500mg / zuva
Chikafu chitsva chinoratidza 55mg / zuva reMucheche uye 220mg / zuva kune Vadiki nevakadzi vepakati
N-acetylneuraminic acid Basa
Memory uye Intelligence kunatsiridza
Nekubatana neuropi cell membranes uye synapses, Sialic acid inowedzera chiyero chekupindura che synapses muuropi tsinga masero, nekudaro kusimudzira kukura kwendangariro nehungwaru.
Masayendisiti ekuNew Zealand akaita ongororo dzakatevedzana kuti asimbise basa rakakosha reasidhi yeshiri mukukura kwenjere dzevana.Pakupedzisira, vatsvakurudzi vakagumisa kuti kuwedzera asidhi yeshiri muvana vacheche kunogona kuwedzera kuwanda kweasidhi yeshiri muuropi, nokudaro kuvandudza kukwanisa kweuropi kudzidza.
Kuvandudza intestinal absorption capacity
Zvinoenderana neyakajeka yemuviri chiitiko chevakomana, iwo maminerari ane mhosva uye mamwe mavhitamini anopinda muura anosanganiswa nyore neakasimba akashata anopomerwa dendere acid, saka intestinal kutorwa kwevhitamini nemamineral.Kugona kwakawedzerwa kubva pairi.
Kurudzira intestinal antibacterial detoxification
Sialic Acid pane cell membrane protein inoita basa rakakosha mukuvandudza kugona kucherechedzwa kwesero, detoxification yecholera toxin, kudzivirira pathological Escherichia coli kutapukira, uye kudzora kwehafu yehupenyu hweprotein.
Kurarama kwenguva refu
Sialic acid ine inodzivirira uye inodzikamisa mhedzisiro pamasero, uye kushomeka kweasilic acid kunogona kukonzera kuderera kwehupenyu hwesero reropa uye kuderera kwe glycoprotein metabolism.
Gadzira mushonga mutsva weSialic Acid
Masayendisiti anoedza kurapa gastrointestinal zvirwere nesialic acid anti-adhesion drugs.Sialic acid anti-adhesive drugs inogona kurapa Helicobacter pylori kurapa gastric ulcers uye duodenal ulcers.
Sialic acid inonzi glycoprotein.Iyo inosarudza kuwirirana uye kusungirirwa kwemasero uye ine kliniki yakafanana anti-inflammatory effects se aspirin.
Sialic asidhi mushonga wepakati kana topical neurological zvirwere uye demyelinating zvirwere;sialic asidhi zvakare chikosoro expectorant.
Sialic acid seyakagadzirwa inogona kugadzira akatevedzana akakosha shuga mishonga, anti-virus, anti-tumor, anti-kuzvimba, uye kurapwa kwesenile dementia kune mhedzisiro yakanaka.
Iyo nzira yekugadzira yeSialic Acid
Zvigadzirwa zvekutanga zvinonyanya shuga, chibage chinodhaka doro, glycerinum, uye magnesium sulfate.Uye isu tinoshandisa tekinoroji yakaviriswa.Munguva iyi, tinoshandisa nzira yekudzivirira kuchengetedza zvinhu zvakachena.Zvadaro ne hydrolysis, kuisa pfungwa, kuomesa, uye kupwanya.Mushure memaitiro ese, tinowana chigadzirwa chekupedzisira.Uye QC yedu inoshandisa HPLC kuyedza mhando yemhando yebatch yega yega tisati taendesa kune vatengi.
Product Name: Sialic acid ;N-Acetylneuraminic asidhi
Rimwe Zita:5-Acetamido-3,5-dideoxy-D-glycero-D-galactonulosonic acid o-Sialic acid Galactononulosonic acid Lactamineic acid NANA N-Acetylsialic acid
Mabviro: Dendere reshiri inodyiwa
Mutsara: 20-98%
Kuonekwa: chena poda yakanaka
CAS NO.: 131-48-6
MW: 309.27
MF: C11H19NO9
Nzvimbo Yekwakabva: China
Kuchengetedza: Chengetedza munzvimbo inotonhorera & yakaoma, chengetedza kure nechiedza chakananga uye kupisa.
Validity: Makore maviri kana akachengetedzwa zvakanaka.
BASA:
1. Anti-virus basa.
2. Anti-kenza basa.
3. Anti-kuzvimba basa.
4. Kudzivirira basa kurwisana nehutachiona hwehutachiona.
5. Kudzora kugona kwe immune system.
6. Kudzora kugona kurwisa pigmentation.
7. Kuchinja kwechiratidzo mumasero etsinga.
8. Ita basa rinokosha mukukura kweuropi uye kudzidza.
9. Sezvinotangira pakugadzirwa kwemishonga yakawanda yemishonga.
