Smoke Tree Extract

Musoro: Premium Smoke Tree Extract 98%Fisetinby HPLC | Natural Antioxidant & Anti-Aging Supplement
Keywords:Fisetin98%, HPLC Yakasimbiswa, Muti Wokusvuta Muti, Natural Antioxidant, Anti-Kuchembera Yekuwedzera

1. Chigadzirwa Overview

Smoke Tree Extract 98% Fisetin inzvimbo yakakwirira-yakachena yemusikirwo inotorwa kubvaCotinus coggygria(Muti Wechiutsi), wakamisikidzwa kusvika pa98% Fisetin kuburikidza nehunyanzvi hwepamusoro-soro hweKushanda Liquid Chromatography (HPLC). Fisetin (C₁₅H₁₀O₆) inonzi flavonoid inozivikanwa neine simba re antioxidant, anti-inflammatory, uye senolytic properties, zvichiita kuti ive chinhu chinotsvakwa-mushure memishonga inovaka muviri, cosmetics, uye kugadzirwa kwemishonga.

2. Madiro Akakosha

• Active Ingredient: Fisetin ≥98% (HPLC)
• Nhamba yeCAS:528-48-3
• Molecular Formula: C₁₅H₁₀O₆
• Kuonekwa: Bright yellow powder
• Solubility: Soluble mu ethanol, DMSO; inonyungudika zvishoma mumvura
• Kunobva Plant:Cotinus coggygriamashizha nemadzinde
• Certifications: GMP, ISO 9001, COA (Sitifiketi Yekuongorora) yakapihwa

3. Kugadzira Maitiro & Kudzora Kwehutano

3.1 Sustainable Extraction

Isu tinoshandisa supercritical CO₂ kudhirowa kuve nechokwadi eco-hushamwari uye solvent-isina kuparadzaniswa kweFisetin, kuchengetedza kwayo bioactive kuvimbika.

3.2 HPLC Kucheneswa & Verification

• Chromatographic Conditions:
  • Koramu: ZORBAX C18 (4.6×150 mm, 5 μm)
  • Mobile Phase: Gradient elution ine 5% acetic acid (Solvent A) uye acetonitrile (Solvent B)
  • Kuonekwa: UV kunyura pa360 nm, nguva yekuchengetedza ≈11.6-12.6 min (inopindirana neFisetin standard)
• Mass Spectrometry (MS):
  • Positive Ion Mode: m/z 287.05487 (C₁₅H₁₁O₆⁺)
  • Negative Ion Mode: m/z 285.03997 (C₁₅H₉O₆⁻)
  • Fragmentation Pateni: Inofananidzwa neyechokwadi Fisetin miyero yekusimbisa chimiro chemolecular.

3.3 Kugadzikana Kwekusimbisa

Fisetin inonzwa kune chiedza uye kupisa. Chigadzirwa chedu chakaiswa muUV-yakachengetedzwa amber girazi ine desiccants kuve nechokwadi kugadzikana panguva yekuchengetedza uye yekufambisa.

4. Applications & Benefits

4.1 Anti-Kuchembera & Senescence

Fisetin inoshanda seanolytic agent, inosarudza kubvisa maseru maseru akabatana nezvirwere zvine chekuita nezera. Zvidzidzo zvinoratidza kuti inosimudzira hupenyu mumamodheru nekuita SIRT1 nzira.

4.2 Neuroprotection

Inoyambuka mhinganidzo yeropa-uropi kuderedza oxidative kusagadzikana, zvinogona kuderedza kufambira mberi kweAlzheimer's uye Parkinson.

4.3 Anti-Inflammatory & Cancer Research

Inogadzirisa NF-κB uye COX-2 nzira, inhibiting pro-inflammatory cytokines. Preclinical data inoratidza apoptosis induction mumasero egomarara.

4.4 Cosmeceuticals

Topical magadzirirwo anonatsiridza elasticity yeganda uye kuderedza UV-induced kukuvara nekuita neutralizing emahara radicals.

5. Kuteerera & Kuchengetedza

• Toxicity Data: LD₅₀> 2000 mg/kg (mumuromo, gonzo), yakarongedzerwa seisina chepfu.
• Regulatory Compliance: Inosangana neUSP, EP, uye FDA nhungamiro yezvekudya zvinowedzera.
• Allergen-Yemahara: Kwete-GMO, gluten-isina, uye vegan-inoshamwaridzika.

6. Packaging & Ordering

• Huripo Saizi: 25 kg/drum (yakawanda), 1 kg (sample)
• MOQ: 1 kg (mienzaniso); 25 kg yemirairo yakawanda.
• Global Shipping: DHL/FedEx ine inotonhora cheni sarudzo dzematunhu anonzwa tembiricha.

7. FAQs

Mubvunzo: Kuchena kunosimbiswa sei?
A: Batch yega yega inoedzwa kaviri kuburikidza neHPLC uye MS, neCOA yakapihwa.

Mubvunzo: Fisetin inogona kutsiva quercetin here?
A: Kunyange zvese zviri flavonoids, fisetin inoratidza yepamusoro bioavailability uye senolytic mhedzisiro.

Mubvunzo: Hupenyu hwesherufu?
A: Mwedzi ye24 kana yakachengetwa pa ≤25 ° C mumidziyo yakavharwa, isina chiedza.

8. Nei Tisarudze?

• R&D Nyanzvi: Kushandisa biosynthesis nzira (semuenzaniso, P450 monooxygenase optimization) yegoho repamusoro.
• Customization: Inogadziriswa kuchena (50% ~ 98%) uye OEM masevhisi aripo.
• Sustainability: Ethanol-mvura inotorwa inopindirana neyakasvibira kemisitisi nheyo.

9. References

1. Gungano reNovel Biosynthetic Pathway yeFisetin Production (2024).
2. HPLC Kuongorora kweFlavonoids muSophora japonica(Yang et al., 2017).
3. A. integrifoliaKubvisa Profileing (Biomedical Sayenzi Tsamba, 2020)