Phosphatidylcholine e na le "hlooho" ea choline le glycerol phospholipids.Mohatla oa glycerol phospholipids e ka ba mefuta e mengata ea mafura a mafura.Hangata, mohatla o le mong ke mafura a mafura a mangata, 'me e' ngoe e na le asiti e sa tsitsang.Empa tse ling tsa tsona ke li-unsaturated mafura acid.Ka mohlala, phosphatidylcholine ea matšoafo ea liphoofolo e na le karolo e phahameng ea dipalmitoyl phosphatidylcholine.
Lebitso la sehlahisoa: Phosphatidylcholine PC
Lebitso le leng: 1,2-diacyl-sn-glycero-3-phosphocholine, PC
Tlhaloso ea Sehlahisoa: Mokelikeli / kapa oaxy solid: hoo e ka bang 60%
Phofo / granule: 10% - 98%,Lintlha tse tsebahalang 20%, 50%, 98%
Mehlala ea Mahala : E teng
Ponahalo: Phofo e 'mala o mosehla kapa o mosehla, oli kapa boka bo tiileng
Mokhoa oa teko: HPLC
Shelf Life: lilemo tse 2
Phosphatidylcholine e na le "hlooho" ea choline le glycerol phospholipids.Mohatla oa glycerol phospholipids e ka ba mefuta e mengata ea mafura a mafura.Hangata, mohatla o le mong ke mafura a mafura a mangata, 'me e' ngoe e na le asiti e sa tsitsang.Empa tse ling tsa tsona ke li-unsaturated mafura acid.Ka mohlala, phosphatidylcholine ea matšoafo ea liphoofolo e na le karolo e phahameng ea dipalmitoyl phosphatidylcholine.
Phosphatidylcholine ke karolo ea mantlha ea biofilm.Mohloli o bonolo haholo ebile o pharaletseng.U ka fumana phosphatidylcholine hoo e ka bang lijong life kapa life bophelong ba hau, eseng feela lehe la mahe kapa soya.Hape ke lecithin mafura a liphoofolo.U ka fumana phosphatidylcholine liseleng tsa limela le liphoofolo.Ha e le hantle, tlhahiso ea khoebo ea phosphatidylcholine ke sehlahisoa se hloekisitsoeng se nang le litaba tse phahameng le phello e tobileng haholoanyane.
Phosphatidylcholine ke ntho ea lipophilic hydrophilic;joala bo tlase bo qhibilihang ka har'a C1 ho ea ho C4, bo sa keneng ka har'a acetone le metsi.
Le hoja ka tloaelo li-PC li sebelisoa ho tšehetsa bophelo bo botle ba boko, li ka boela tsa tšehetsa sebete le ho laola maemo a k'holeseterole.
Choline e ka tšela mokoallo oa mali bokong habonolo haholo ka mokhoa oa ho hasanya o sa tsitsang, 'me liphetoho tsena tsa plasma li ka hlahisa liphetoho tse tšoanang maemong a choline ea boko.
Ka lebaka la phetoho e sa lekaneng ea phetoho ea choline, e sa khotsofatsoang ka ho feletseng ke karoloana ea choline, lihlahisoa tsa choline ka plasma lia eketseha, tse khothalletsang ho thehoa ha acetylcholine le phosphorylcholine le ho lokolloa ha acetylcholine.Haeba litaba tsa li-precursors tse ling tsa phosphatidylcholine li eketseha, mokhoa oa ho fetola choline ho phosphatidylcholine le keketseho ea litaba tsa lierekisi lia eketseha.Boemo ba li-membrane tsa synaptic bokong boa eketseha.Choline e entsoe ka metabolized ho betaine sebeteng, e leng tsela e kholo ea ho nchafatsa methionine le S-adenosylmethionine ho fana ka sehlopha sa methyl.
Boholo ba metabolism ea sebete bo hlaha ka har'a lera la sele le nkang lisekoere-mithara tse 33,000 tsa 'mele oa motho.
Ho na le lilemo tse fetang 20 tsa liteko tsa kliniki tse bontšitsoeng hore PC e sireletsa sebete ho tsoa liphellong tse ngata tse chefo tse senyang li-membrane tsa lisele, tse kang tahi, lithethefatsi, litšila, likokoana-hloko le liphello tse ling tse chefo.
Ntho e 'ngoe ea surfactant ea PC ke karolo e ka sehloohong ea lera la sele le matšoafo, e tsamaisang pakeng tsa lera la sele ka phosphatidylcholine phetisetso protheine (PCTP).E boetse e bapala karolo ea phetisetso ea lets'oao la sele ea membrane-mediated le ts'ebetso ea PCTP ea li-enzyme tse ling.
Ho na le ntlha e ferekanyang mona.Lecithin ha se phosphatidylcholine.Phosphatidylcholine ke karolo ea bohlokoa ea lecithin.
Melemo ea phosphatidylcholine
Sireletsa sebete ho tsoa kotsi
Ho ntlafatsa Mosebetsi oa Kelello
Ho thibela litla-morao tsa lithethefatsi
Phello ea boselamose e khahlanong le botsofali e kenyellelitsoe ho litlolo
Ho senyeha ha lipid
Ho sebetsana le lefu la ulcerative colitis
Ho ea ka palo e kholo ea liteko tsa liphoofolo, PC supplementation e ka eketsa acetylcholine (neurotransmitter bokong), e leng tekanyo ea bohlokoa ea ho ntlafatsa mohopolo.Liphuputso tse ling li ntse li tsoela pele ho bona liphello tsa PC le limatlafatsi tse ling ho ntlafatsa mohopolo ho litoeba tsa 'dementia'.Hoa tsebahala hore PC le limatlafatsi tse ling li na le liphello tse itseng tse ntle le liphello tse sebetsang, empa ho hlokahala liteko tse ngata.Ka botebo, ka 2017, ho bile le lithuto tse amanang le maemo a phosphatidylcholine le lefu la Alzheimer's.
Sebete ke setho sa bohlokoa 'meleng oa motho,' me mesebetsi e meng ea bophelo ba letsatsi le letsatsi e ka baka moroalo o moholo sebeteng, e leng se tloaelehileng sebeteng sa mafura le ho thatafala ha sebete.
Lijo tse nang le mafura a mangata li ka ba le phello e mpe sebeteng.Ke ’nete hore sebete se ka boela sa senngoa ke chefo ea tahi, lithethefatsi, lintho tse silafatsang, livaerase le liphello tse ling tse chefo, ’me ho thata haholo ho lokisoa.Lilemong tse fetileng tsa 20 tsa liteko tsa meriana, ho sibolloa ha phosphatidylcholine ha hoa ka ha phetha karolo ea bohlokoa ts'ebetsong ea ho pholosa bophelo.Ho ka boleloa hore phello e hlile e sa khotsofatse, empa kaha sildenafil e ne e etselitsoe ho etsa moriana oa phekolo ea pelo, liphello tse ling li ile tsa fumanoa likarolong tsa morero oa teko.Ka ho hlahloba ka hloko, re ka fumana phello ea tšireletso ea PC sebeteng ho ea ka phepelo ea phosphatidylcholine le phello ea eona e sireletsang lera la sele.Kaha e ke ke ea lokisoa, e ka sireletsoa esale pele, e leng karolo e kholo ea phosphatidylcholine.
Le hoja phosphatidylcholine e sebelisoa e le tlatsetso ea phepo e nepahetseng bakeng sa ho noa ka molomo, ha e kena-kenane le thepa ea eona e sa tšoaneng.Ho ea ka thepa ea eona e khethehileng ea 'mele le ea likokoana-hloko, e ka kenella habonolo letlalong' me ea eketsa ho kenella ha lihlahisoa tse ling.Ka hona, bahlahisi ba bangata ba ikemiselitse haholo ho sebelisa phosphatidylcholine ka litlolo tsa bona tsa ka ntle tsa tlhokomelo ea letlalo ho etsa letlalo le boreleli le le mongobo.Phosphatidylcholine e boetse e bontšitse litholoana tse ntle kalafong ea makhopho, ka phokotso ea 70% ea boemo ba leholimo kamora matsatsi a 28.
Phosphatidylcholine ke molek'hule ea bohlokoa ea likokoana-hloko e ka fumanoang seleng e 'ngoe le e' ngoe ea 'mele oa motho.Bo-rasaense ba bang ba lekile ka litoeba tse fetotsoeng liphatsa tsa lefutso ho hlahisa tšenyo ea oxidative le ho potlakisa botsofali ho ithuta liphello tsa phosphatidylcholine botsofaling, ntlafatso ea kelello le ho ntlafatsa mohopolo ho bakuli ba Alzheimer.Ha e le hantle, bo-rasaense ba bang ba lumela hore tlatsetso ea phosphatidylcholine ho phekola lefu la Alzheimer ha e e-s'o be le bopaki bo lekaneng.Empa lebelo la ho theha lefatše le se nang Alzheimer le ke ke la emisa.Ha e le hantle, re ke ke ra thibela monyetla oa hore phosphatidylcholine e na le karolo, empa re hloka liteko tse eketsehileng le tse khōloanyane ho paka karolo ea eona e tobileng.
Litla-morao tsa phosphatidylcholine
Haholo-holo e bonts'itsoeng karolong ea bongaka, lihlahisoa tse nang le PC tse nang le lijo li ka nkoa ho latela litaelo;ha e sebelisoa meriana, e lokela ho latela ka tieo litaelo tsa lingaka le baetsi ba lithethefatsi bakeng sa tšebeliso ea lithethefatsi.E le ho qoba likotsi tsena tsa litla-morao, ho qala ka tekanyo e tlaase ka ho fetisisa e ka khonehang, tekanyo e phahameng ka ho fetisisa e finyelloa butle-butle.
PC ea molomo e ka lebisa ho fufuleloa ho feteletseng.Ho nka ligrama tse fetang 30 ka letsatsi ho ka lebisa ho letšollo, ho nyekeloa ke pelo kapa ho hlatsa.
Ho kenya PC ka ho toba lihlahala tsa mafura ho ka lebisa ho ruruha ho matla kapa fibrosis.E ka boela ea lebisa ho bohloko, ho chesa, ho hlohlona, ho tsitsisa ha mali, edema le bofubelu ba letlalo
Lisebelisoa tsa PC li ka sebelisoa ka capsule le sebopeho sa metsi ntle le lengolo la ngaka.Li nkoa li sireletsehile ha li sebelisoa ka nako e khutšoanyane joalokaha li laetsoe.Ente ea PC e tlameha ho laoloa ke litsebi tsa bophelo bo botle.
