I-Naringenin 98%

I-Naringenin inohlaka lwamathambo e-flavanone enamathathuamaqembu e-hydroxykumakhabhoni angu-4, 5, no-7.Ingatholakala kokubili ku-i-aglycolifomu, i-naringenin, noma kuyoi-glycosidicifomu,naringin, enokwengezwa kwei-disaccharide i-neohesperidosisenamathiselwe nge-ai-glycosidicukuxhumana ku-carbon 7.Njengeningi lama-flavanones, i-naringenin inesikhungo esisodwa se-chiral ku-carbon 2, okuholela ekuthenienantiomericamafomu e-compound.Ama-enantiomers atholakala ngezilinganiso ezihlukene emithonjeni yemvelo.I-Racemizationye-S(-)-naringenin ikhonjiswe ukuthi yenzeka ngokushesha.I-Naringenin iboniswe ukuthi imelana ne-enatiomerization ngaphezu kwe-pH 9-11.

Ukuhlukaniswa nokuhlaziywa kwama-enantiomers kuhlolwe iminyaka engaphezu kwengu-20, ikakhulukazi ngokusebenzisaukusebenza okuphezulu kwe-chromatography ye-liquidezigabeni zokuma ze-chiral ezitholakala ku-polysaccharide.Kunobufakazi obusikiselai-stereospecific i-pharmacokineticsfuthii-pharmacodynamicsamaphrofayili, okuhlongozwe ukuba kube incazelo yezinhlobonhlobo ze-bioactivity ebikiwe ye-naringenin.

I-Naringenin kanye ne-glycoside yayo itholakale ezinhlobonhlobo zeamakhambifuthiizithelo, kuhlanganiseisithelo segilebhisi,i-bergamot, owolintshi omuncu, ama cherry, utamatisi, ukhokho,I-oregano yesiGreki, amanzi eminti,i-drynariakanye nakuubhontshisi.Izilinganiso ze-naringenin ku-naringin ziyahlukahluka phakathi kwemithombo, njengoba kwenza izilinganiso ze-enantiomeric.

I-Naringenin Yemvelo Ehlanzekile

CAS#:480-41-1

[Igama lesiNgisi]:Naringenin
[Imininingwane]: 98%
[Izakhiwo zomkhiqizo]:impushana emhlophe
[Indlela yokuhlola]: HPLC
[Ifomula]:C15H12O5
[CAS.NO]:480-41-1
[Isisindo sengqamuzana]:272.25 g•mol−1
I-Melting Point & Solubility:mp251°C,Incibilika otshwaleni, i-ether ne-benzene.cishe engancibiliki emanzini.

Igama Lomkhiqizo:I-Naringenin98%

Ukucaciswa:98% nge-HPLC

Igama lomkhiqizo: Naringenin

Umthombo wezitshalo: Citrus grandis(L.) Osbeck

I-CAS NO.480-41-1

Ukubukeka: Impushana emhlophe noma evaliwe

Isimo se-GMO:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

1. I-Naringenin inomphumela wokulwa nomdlavuza, ingabulala amangqamuzana omdlavuza ahlukahlukene.

2. I-Naringenin inomphumela wokuvikela ekugxilweni kwe-ischemia ye-ischemia egxile kumagundane , futhi indlela yayo ingase ihlobane nokukhishwa kwayo okuphumelelayo kwama-radicals mahhala.I-Naringenin yehlise kakhulu okuqukethwe kwamanzi ebuchosheni, yehlisa umthamo we-cerebral infarction ye-hemisphere yobuchopho ekhubazekile, yehlisa izinga le-MDA futhi yathuthukisa umsebenzi we-SOD ebuchosheni.Lokhu kukhombisa ukuthi i-Naringenin ingaba nomthelela wokuvikela ku-hemisphere yobuchopho.

3. I-Naringenin ingehlisa ngokuphawulekayo ukugcwala kwe-cholesterol eplasma kanye ne-hepatic cholesterol content.

4. I-Naringenin ikhonjisiwe futhi ukuthi yehlisa ukukhiqizwa kwegciwane le-hepatitis C ngama-hepatocyte anegciwane (amaseli esibindi)

isiko lamaseli .Lokhu kubonakala kungokwesibili emandleni e-Narigenin okuvimbela ukugcinwa kwe-lipoprotein ephansi kakhulu ngamaseli.

5.I-Naringenin inomphumela we-bioactive empilweni yomuntu njenge-antioidant, i-radical scavenger yamahhala, i-antisepsis, i-anti-inflammatory, umsebenzi we-antispasmodic.

Isicelo

1.Isifo i-Alzheimer's

I-Naringenin isacwaningwa njengendlela yokwelapha engase ibe khona ye-Alzheimer's Disease.I-Naringenin iye yaboniswa ukuthuthukisa inkumbulo nokunciphisa amaprotheni e-amyloid kanye ne-tau ocwaningweni olusebenzisa imodeli yegundane ye-Alzheimer's Disease.

2.I-antibacterial, antifungal, ne-antiviral

Kunobufakazi bemiphumela elwa namagciwane ku-H. pylori.I-Naringenin nayo ikhonjiswe ukuthi yehlisa ukukhiqizwa kwegciwane le-hepatitis C ngama-hepatocyte anegciwane (amaseli esibindi) kusiko lamaseli.Lokhu kubonakala kungokwesibili emandleni e-naringenin okuvimbela ukukhiqizwa kwe-low-density lipoprotein ngamaseli.Imiphumela ye-antiviral ye-naringenin okwamanje ingaphansi kophenyo lomtholampilo.Imibiko yemiphumela elwa namagciwane ku-polioviruses i-HSV-1 ne-HSV-2 nayo yenziwe, nakuba ukuphindaphindeka kwamagciwane kungavinjelwa.

3. I-Antioxidant

I-Naringenin iboniswe ukuthi inezinto ezibalulekile ze-antioxidant.

I-Naringenin iphinde yaboniswa ukunciphisa ukulimala kwe-oxidative ku-DNA in vitro nasezifundweni zezilwane.