Osthole 98%

I-Fructus cnidii (i-Common Cnidium) isitshalo saminyaka yonke, ukuphakama okungama-30-80cm.Iqabunga le-Fructus cnidii liyashintshana, i-compundumbel inflorescence.Cremocarp, ellipsoidal, 2-4 mm ubude, cishe 2 mm ububanzi.Ngaphandle ngokumpunga-ophuzi noma onsundu ngokumpunga;enama-stylopod angu-2 aphendukile esiqongweni, futhi ngezinye izikhathi anesiqu esihle sesithelo esisekelweni.Ingaphezulu le-dorsal lama-mericarps anama-ridge amahlanu azacile nabude ubude, indawo ye-commissural eyisicaba, enezimbambo zobude ezimbili ezinsundu neziphakeme kancane.I-pericarp ye-Fructus cnidii ixega futhi iphuka kalula, ikhuhlwa kalula, inhlanyelo incane, nsundu ngokumpunga futhi inamafutha.Iphunga, iphunga;ukunambitheka, okubabayo, okupholile futhi ndikindiki.

I-Osthol, eyaziwa nangokuthi i-methoxyparsley, i-parsley methyl ether, iyinhlanganisela ye-coumarin, ku-ambrella plant osthol okuqukethwe kuphezulu, okubizwa ngokuthi i-osthol.Ngo-1909, u-Herzog no-Krohn bathola okokuqala i-osthol ehlanganisiwe ezimpandeni zesitshalo sesambulela i-europhus.Njengamanje, itholakala kakhulu ezitshalweni, ikakhulukazi ku-umbelliferae kanye ne-rutaceae, kanye nakuma-compositae ambalwa kanye nemifino.
I-cnidium cnidium yokuhweba ikhishwa kakhulu esithelweni esomisiwe nesivuthiwe se-cnidium cnidium.I-Cnidium isatshalaliswa kakhulu ku-guangxi, i-jiangsu, i-anhui, i-shandong, i-hebei, njll. Ngenxa yemisebenzi yayo ehlukahlukene yebhayoloji, i-cnidium isetshenziswa kakhulu kwezimonyo, kwezokwelapha nakwezolimo.

Igama lomkhiqizo:Osthole 98%

Ukucaciswa:98% yi-HPLC

Igama lesiLatini:C.monnieri (L.) Cusson

Umthombo we-Botanic:I-Common Cnidium Fruit Extract

Inombolo ye-CAS:484-12-8

Ingxenye Yesitshalo Esetshenzisiwe:Imbewu

Umbala:Onsundu kuya kokumhlophe okuyimpushana ecolekile enephunga elibonakalayo kanye nokunambitha

Isimo se-GMO:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

Imisebenzi:

-I-Osthole ingakhuphula ukuphuma kwesidoda, ivuse isifiso socansi futhi ibe nesenzo sokuvusa inkanuko

-Osthole uyakwazi ukomisa umswakama abulale izimpethu, akhiphe amakhaza akhiphe umoya, afudumale izinso

qinisa yin.

-I-Osthole inomsebenzi wokukhulula isifuba somoya kanye ne-antifungus, i-antivirus.

Umphumela we-Antiarrhythmic

Ukukhishwa kwamanzi kanye ne-coumadin ephelele evela ku-fructus cnidium kunemiphumela ecacile yokuvimbela i-chloroform eyenza i-ventricular fibrillation kumagundane kanye ne-calcium chloride eyenza i-ventricular fibrillation kumagundane.I-Fructus cnidium ne-zanthoxylum acetaminophen nazo zinalo mphumela we-pharmacological futhi zingathuthukisa i-ventricular electrofibrillation threshold konogwaja.Ukukhishwa kwamanzi, i-coumarin ephelele, i-cnidium, ne-phenols ye-zanthoxylum ibe nemiphumela ebalulekile yokuvimbela ukuhamba kwe-sodium ion kulwelwesi lweseli lwe-myocardial.

I-Antihypertensive, inhibition of vascular dilatation

I-Osthol ibe nomthelela ongemuhle we-inotropic oncike kumthamo ku-atrium yangakwesobunxele ye-Guinea pigs ehlukanisiwe kanye nomthelela ongemuhle wemvamisa ku-atrium yangakwesobunxele yezingulube ze-Guinea pigs.Ngaphezu kwe-polarization ebangelwa i-norepinephrine, i-CaCl2 kanye ne-K+ ephezulu, ijika le-aorta contraction dose-response curve lashintshelwa kwesokudla futhi impendulo ephezulu yehla, okubonisa indima ye-biosynthetic compound ekuphumuleni kwe-vascular smooth muscle.I-Fructus cnidium inomphumela othile we-antihypertensive.

Imiphumela ohlelweni lokuphefumula

I-Cnidium monnieri ingqikithi ye-coumarin ngokuphumula kwezidakamizwa (i-histamine ne-acetylcholine) okubangelwa ama-bronchial spasms kanye nendima ye-diastole bronchus ngokuqondile, lo msebenzi ungaba i-B - adrenaline receptor blockers block by propranolol, amagundane ngemva kwengqikithi ye-coumarin cnidium monnieri, ngokusobala ukwandisa inani le-phenol ebomvu. ukudonsa emzimbeni, kubonisa isenzo esinamandla se-expectorant.

Imiphumela elwa nokuvuvukala

I-Cnidium cnidium ne-phenolic zanthoxylum zingavimbela ukuvuvukala kwegobolondo lendlebe lamagundane okubangelwa i-xylene kanye nokwanda kokungena kwe-capillary emgodini wesisu okubangelwa i-acetic acid.I-Osthol ne-acetonol ibe nemiphumela ebalulekile yokuvimbela ukuvuvukala kwezinyawo kumagundane namagundane ane-bilateral adrenal resection.I-Osthol ingase futhi inciphise okuqukethwe kwe-PGE ezicutshini ezivuvukalayo zengxenye yonyawo oluvuvukalayo kumagundane, kodwa i-osthol ayizange ithinte okuqukethwe kwe-PGE ezicubu ezivuthayo zengxenye yonyawo oluvuvukalayo kumagundane.

Imiphumela ohlelweni lwezinzwa

I-coumarin ephelele ye-cnidium cnidium inomphumela ovimbelayo ohlelweni lwezinzwa oluphakathi.I-Osthol ingathuthukisa kakhulu umphumela wokulutha we-pentobarbital sodium kumthamo we-subthreshold hypnotic kumagundane, futhi lo mphumela we-hypnotic uhlobene nomthamo.I-Cnidium cnidium ingakhuthaza ukufunda nokukhumbula amagundane, futhi ithuthukise kakhulu ukutholwa kwenkumbulo, ukuhlanganiswa kanye nomphumela oqondile we-Antiarrhythmic.

Ukukhishwa kwamanzi kanye ne-coumadin ephelele evela ku-fructus cnidium kunemiphumela ecacile yokuvimbela i-chloroform eyenza i-ventricular fibrillation kumagundane kanye ne-calcium chloride eyenza i-ventricular fibrillation kumagundane.I-Fructus cnidium ne-zanthoxylum acetaminophen nazo zinalo mphumela we-pharmacological futhi zingathuthukisa i-ventricular electrofibrillation threshold konogwaja.Ukukhishwa kwamanzi, i-coumarin ephelele, i-cnidium, ne-phenols ye-zanthoxylum ibe nemiphumela ebalulekile yokuvimbela ukuhamba kwe-sodium ion kulwelwesi lweseli lwe-myocardial.

I-Antihypertensive, inhibition of vascular dilatation

I-Osthol ibe nomthelela ongemuhle we-inotropic oncike kumthamo ku-atrium yangakwesobunxele ye-Guinea pigs ehlukanisiwe kanye nomthelela ongemuhle wemvamisa ku-atrium yangakwesobunxele yezingulube ze-Guinea pigs.Ngaphezu kwe-polarization ebangelwa i-norepinephrine, i-CaCl2 kanye ne-K+ ephezulu, ijika le-aorta contraction dose-response curve lashintshelwa kwesokudla futhi impendulo ephezulu yehla, okubonisa indima ye-biosynthetic compound ekuphumuleni kwe-vascular smooth muscle.I-Fructus cnidium inomphumela othile we-antihypertensive.

Imiphumela ohlelweni lokuphefumula

I-Cnidium monnieri ingqikithi ye-coumarin ngokuphumula kwezidakamizwa (i-histamine ne-acetylcholine) okubangelwa ama-bronchial spasms kanye nendima ye-diastole bronchus ngokuqondile, lo msebenzi ungaba i-B - adrenaline receptor blockers block by propranolol, amagundane ngemva kwengqikithi ye-coumarin cnidium monnieri, ngokusobala ukwandisa inani le-phenol ebomvu. ukudonsa emzimbeni, kubonisa isenzo esinamandla se-expectorant.

Imiphumela elwa nokuvuvukala

I-Cnidium cnidium ne-phenolic zanthoxylum zingavimbela ukuvuvukala kwegobolondo lendlebe lamagundane okubangelwa i-xylene kanye nokwanda kokungena kwe-capillary emgodini wesisu okubangelwa i-acetic acid.I-Osthol ne-acetonol ibe nemiphumela ebalulekile yokuvimbela ukuvuvukala kwezinyawo kumagundane namagundane ane-bilateral adrenal resection.I-Osthol ingase futhi inciphise okuqukethwe kwe-PGE ezicutshini ezivuvukalayo zengxenye yonyawo oluvuvukalayo kumagundane, kodwa i-osthol ayizange ithinte okuqukethwe kwe-PGE ezicubu ezivuthayo zengxenye yonyawo oluvuvukalayo kumagundane.

Imiphumela ohlelweni lwezinzwa

I-coumarin ephelele ye-cnidium cnidium inomphumela ovimbelayo ohlelweni lwezinzwa oluphakathi.I-Osthol ingathuthukisa kakhulu umphumela wokulutha we-pentobarbital sodium kumthamo we-subthreshold hypnotic kumagundane, futhi lo mphumela we-hypnotic uhlobene nomthamo.I-Cnidium cnidium ingakhuthaza ukufunda nenkumbulo yamagundane, futhi ithuthukise ngokuphawulekayo ukutholwa kwenkumbulo, ukuhlanganiswa nokubandlululwa kwesiqondiso samagundane.

Anti-mutagenesis, anti-cancer effect

I-Cnidium, i-parsley b, i-bergamot lactone, i-isorhein, i-zanthoxylum acetaminophen kanye ne-zanthoxylum toxin inomsebenzi ophezulu ekuvimbeleni i-mutagenesis ye-aflatoxin B1.Ukukhishwa kwamanzi kwe-cnidium kungavimbela i-S130 sarcoma, kunwebe izinsuku zokuphila futhi kuvimbele ukukhula kwesimila.

Anti-mutagenesis, anti-cancer effect

I-Cnidium, i-parsley b, i-bergamot lactone, i-isorhein, i-zanthoxylum acetaminophen kanye ne-zanthoxylum toxin inomsebenzi ophezulu ekuvimbeleni i-mutagenesis ye-aflatoxin B1.Ukukhishwa kwamanzi kwe-cnidium kungavimbela i-S130 sarcoma, kunwebe izinsuku zokuphila futhi kuvimbele ukukhula kwesimila.

Izicelo:

I-Osthole isetshenziswa kakhulu emikhiqizweni ye-heath.I-Osthole ingasetshenziswa njengomkhiqizo we-tonic ekusweleni kwamadoda, izithako ezisebenzayo zemithi yezifo zabesifazane.

I-Osthole isetshenziswa kakhulu emikhakheni yemikhiqizo yemithi.I-Osthole iphinde isetshenziswe njengomkhiqizo we-tonic ku-acute exudative skin disease.

Abahlinzeki abambalwa bezinto zokusetshenziswa njengesiqinisekiso sokuhlinzekwa.Izikhungo Zokubambisana Eziqinile ezizokwesekaI-Institute of botany/Institution of microbiology/Academy of Science and Technology/University