Singakwazi ukugcwalisa kalula amakhasimende ethu ahlonishwayo ngekhwalithi yethu enhle kakhulu ephezulu, ithegi yentengo enhle kakhulu nokusekelwa okuhle kakhulu ngenxa yokuthi besingochwepheshe ngokwengeziwe futhi sisebenza kanzima kakhulu futhi sikwenza ngendlela engabizi kakhulu ye-Popular Design yase-China CAS 1094 -61-7 99% NmnI-Nicotinamide Mononucleotide Powder, Samukela amakhasimende amasha naphelelwe yisikhathi avela kuyo yonke imikhakha yokuphila kwansuku zonke ukuze akhulume nathi ngezinhlangano zamabhizinisi ezizayo kanye nempumelelo efanayo!
Singakwazi ukugcwalisa kalula amakhasimende ethu ahlonishwayo ngekhwalithi yethu enhle kakhulu ephezulu, ithegi yentengo enhle kakhulu nokusekelwa okuhle kakhulu ngenxa yokuthi besinochwepheshe abaningi futhi sisebenza kanzima kakhulu futhi sikwenza ngendlela eyongayoI-China Nmn Powder, Whitening Izithako, Imikhiqizo nezixazululo zinedumela elihle ngentengo yokuncintisana, indalo eyingqayizivele, ehola izitayela zembonini.Inkampani igcizelela umgomo wokuwina-win umqondo, isungule inethiwekhi yokuthengisa yomhlaba wonke kanye nenethiwekhi yesevisi yangemuva kokuthengisa.
I-Nicotinamide mononucleotide bulk powder
Igama lomkhiqizo:I-Nicotinamide mononucleotide powder
Omqondofana: NMN,β-Nicotinamide Mononucleotide,beta-Nicotinamide Mononucleotide
Inombolo ye-CAS: 1094-61-7
Imininingwane: 99% iminithi
I-Molecular Formula:C11H15N2O8P
Isisindo samangqamuzana: 334.221 g/mol
Iphakheji: 1kg/isikhwama, 25kg/isigubhu
Iyini iNicotinamide Mononucleotide?
I-Nicotinamide mononucleotide, efushanisiwe njengeNMN, inamagama alandelayo:
β-NMN, BETA-Nicotinamide Mononucleotide;
I-BETA-NMN;I-BETA-NICOTINAMIDE MONONUCLEOTIDE;
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;
I-NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-PHOSPHATE;I-NICOTINAMIDE RIBOTIDE;
I-NICOTINAMIDE MONONUCLEOTIDE
I-NMN ikhona ezintweni eziphilayo ezihlukahlukene kuhlanganise nabantu futhi iyinhlanganisela ebalulekile ekugcineni imisebenzi yomzimba.I-NMN iphinda isetshenziswe ngemva kokugaywa umzimba, futhi i-vitamin B3 ekudleni ingaphinda ihlanganise i-NMN.
Ngaphambi kokuba siqonde i-nicotinamide mononucleotide, sidinga ukwazi ukuthi iyini.I-Nicotinamide mononucleotide (NMN) isandulela esibalulekile se-NAD+, futhi i-NAD+ iyindlela ebalulekile yokulungisa amaseli kubantu.Lapho abantu besezinsaneni nasezinganeni ezincane, ukukhula nokukhula kwabo kuyashesha kakhulu, futhi ngokukhula kweminyaka, ukusebenza komzimba womuntu kuzokwehla kancane kancane.Isibonelo esilula sifana nesidala;uzophuphuthekiswa ngengozi.Amaqhubu adilizwa, okubi nakakhulu ukuthi balimala kabi.Enqubweni yokuguga kwamangqamuzana omuntu, inani le-NAD+ lizoncipha kakhulu uma liqhathaniswa nesikhathi esedlule ngenxa yemetabolism kanye nomzimba ngokwawo.
I-Nicotinamide mononucleotide iyingxenye ebalulekile yokuvuselelwa komuntu.Ososayensi emhlabeni wonke bathole ukuthi i-nicotinamide mononucleotide inomphumela othile ekugugeni.Ocwaningweni olujulile, isihluthulelo se-nicotinamide mononucleotide ukuthi iyisandulela se-NAD+, esizoguqulela i-NAD+, yengeze isici sokulungisa amangqamuzana emangqamuzaneni omuntu, imelane nenqubo yokuguga, futhi ibe nethuba lokuqala kabusha umsebenzi wokukhula kabusha iseli, okuwumsebenzi wokunweba ukuphila kwe-nicotinamide mononucleotide.
I-Nicotinamide mononucleotide ngokwemvelo ikhona kuwo wonke amangqamuzana omzimba wethu futhi iyingxenye ebalulekile yokuzilungisa komzimba.Kuyi-metabolite yokugcina i-NAD+ biosynthesis evamile, futhi le nto ingalawula i-physiology ngesikhathi sokujikeleza komzimba, naku-pathology ethile.Idlala indima ebalulekile ekusebenzeni kwamangqamuzana.
Izithasiselo eziqukethe i-NMN
Kunemikhiqizo eminingi ye-NMN edayiswayo manje.Ezinye zidumile phakathi kwabasebenzisi bokugcina, njenge-NMN Pure, Ultra NMN, njll. ku-Amazon nakwezinye izitolo ze-inthanethi.
Amanye amafomula ane-NNN kuphela kuwo, futhi amanye ahlangene nezinye izithako ezilwa nokuguga ezisebenzayo, njenge-resveratrol, i-pterostilbene, ibonise ukukhishwa kwezimpande, njll.
Womabili amafomu e-capsule nawethebhulethi ayatholakala, ngezansi kukhona amaqiniso ezithako ze-NMN avela kwamanye amalebula e-NMN:
I-125mg ibonakala iyisilinganiso esithandwayo sezithako eziningi ze-NMN, nakuba abanye bebhala i-260mg nge-capsule ngayinye kumalebula abo ngosayizi wokukhonza wama-capsules we-2 noma amaphilisi nsuku zonke.Awukho umthamo onconyiwe osemthethweni njengamanje.
Indlela yokusebenza ye-nicotinamide mononucleotide
I-nicotinamide mononucleotide iguqulwa ibe “i-nicotinamide adenine dinucleotide (NAD)” into ebalulekile kumetabolism yamandla emzimbeni.Ocwaningweni lwegundane, kwaqinisekiswa ukuthi i-nicotinamide mononucleotide ingavula isakhi sofuzo esibizwa nge-acetylase emzimbeni, ngaleyo ndlela ibe nemiphumela efana nokwelula impilo nokwelapha isifo sikashukela.I-NAD iyinto engakhiqizwa umzimba womuntu.Ucwaningo lukhombisile ukuthi okuqukethwe kwe-NAD emzimbeni kuncipha ngokuya ngeminyaka.
Ukwanda kokuvuvukala okuhambisana nokuguga kungase kuphazamise ikhono lomzimba lokukhiqiza i-NMN, okubuye kubangele ukwehla kwe-NAD.
I-NMN iyisandulela se-coenzyme NAD+ ebalulekile emzimbeni.I-Nicotinamide mononucleotide iyindima ebalulekile ekukhiqizeni amandla amangqamuzana omuntu, futhi ibandakanyeka ekuhlanganisweni kwe-intracellular NAD+ (nicotinamide adenine dinucleotide, i-coenzyme yokuguqulwa kwamandla eseli).
I-NMN yaziwa ngokusemthethweni njengento yokuqala yemvelo emhlabeni eqinisekiswa ukuhlola okuqinile kwesayensi ukubuyisela emuva ngempumelelo nokubambezela ukuguga nokwelula impilo.
Ngo-2017, izifundo zibonise ukuthi i-NMN ingaphatha i-NR ne-NMN ataxia, futhi i-NR ayiguquli umsebenzi we-SIRT3 noma ithuthukise umsebenzi wenhliziyo.
Ukunikezwa kwe-NAD + ngeke kume - kuzoqhubeka kudliwe futhi kugcwaliswe, futhi lonke i-NAD + ichibi liphenduka izikhathi ezi-2-4 ngosuku.
Lo mjikelezo ungezindlela zokulungisa, lapho i-enzayimu i-Nampt ivuselela i-NAM iye ku-NMN bese igaywa ku-NAD +.I-Namp iyisinyathelo somkhawulo wejubane ohlelweni lokudoba.
I-Nicotinamide Mononucleotide VS.I-Nicotinamide Riboside
Namuhla, umhlaba ucebile ocwaningweni oluhlukahlukene nge-NR, futhi ukuhlolwa komzimba womuntu kwenza umphumela we-NR kudatha yethiyori ube ngcono kune-NMN.Kodwa-ke, ucwaningo luye lwabonisa ukuthi i-NR iqala ukusebenza emzimbeni womuntu futhi isadinga ukuba nolwazi okwesikhashana.Ukhiye wukuthi kokubili i-NR ne-NMN zingamanduleli we-NAD+, kuyilapho i-Nicotinamide Riboside (NR) iyisandulela se-NMN ne-NAD+, ngakho i-NR iyashintsha.Kuthatha isikhashana ngaphambi kwe-NAD+.Uma kuqhathaniswa nomthelela osheshayo we-NMN, imizuzu engu-15 ye-NR iyigebe elikhulu.
Kungabonakala kumdwebo womjikelezo ongenhla ukuthi i-NAMPT iyisici esibalulekile esikhawulela ukukhiqizwa kwe-NMN.Njengoba iminyaka ikhula, akuwona umzimba womuntu ongafuni ukuba mncane, kodwa umsebenzi we-enzyme we-NAMPT wehla lapho kunikezwa amandla nezakhi.Njengoba umjikelezo we-NAM uncishiswa, isitoko se-NAD+ sincishiswa ngokwemvelo.
I-NR ingaguqulelwa ku-NMN noma iye ku-NAM, kuye ngendima ye-enzyme ye-Nrk1 ukuze kunqunywe ukuthi iyiphi into yekhwalithi efanayo ye-NR ezokhiqiza okwengeziwe.Uma iguqulelwa ku-NAM, iphinde ivinjelwe yi-enzyme ye-NAMPT.Uma kuqhathaniswa nesenzo esiqondile se-NMN sokukhiqiza i-NAD+, umphumela wenani elilinganayo le-NR ngokusobala uba buthaka kakhulu.
Kungani ungathathi i-NAD+?
I-NAD+ ayikwazi ukungeniswa ngokuqondile kumaseli ngokuphathwa ngomlomo ngenxa yesisindo sayo samangqamuzana eseqile.Isengezo se-NAD+ sitholwa kuphela ngokungenisa isandulela se-NAD+ yesisindo samangqamuzana amancane.
Kodwa-ke, i-NMN ingenziwa ibe imikhiqizo ehlukahlukene, okungaba amaphilisi, amaphilisi, noma ama-granules ngenxa yemvelo yayo encibilikayo.Ukuncibilika kwe-NMN emanzini ngu-35mg/ml.
Ngalo mqondo, i-NMN ingcono kakhulu kune-NAD+, futhi iqonde kakhulu kune-nicotinamide riboside.
Izinzuzo zeNicotinamide Mononucleotide
Imiphumela eyinhloko ye-NMN imi kanje:
- i-anti-oxidation
- Ukukhulula ukwehla ngokomzimba
- Ukulungiswa kwe-DNA
- Sekela imiphumela ye-neuroprotective
- Thuthukisa ukusebenza kwenhliziyo futhi uvikele inhliziyo
- Thuthukisa isimo seziguli ze-Alzheimer's
Isici esihluke kakhulu se-NMN ukuthi ingahlehlisa ukuguga futhi yelule impilo.
Imiphumela emibi yeNicotinamide Mononucleotide
Njengoba i-NMN okwamanje yenza ukuhlola kwezilwane kuphela, ukuhlola kwabantu ngezinga elikhulu akukakaqali, ngakho imiphumela engemihle enganqunywa ayikacaci.Kodwa-ke, ngokusho kwendlela yokusebenza ye-NMN, kungachazwa ukuthi iziguli ezinomdlavuza akufanele ziwuthathe ngangokunokwenzeka.Ngoba ukuguqulwa kwe-NMN kukhuthaza ukukhiqizwa kwe-NAD+, kuyilapho amangqamuzana omdlavuza ejwayela ukwenza kancane kancane imisebenzi yomzimba, ukwanda kwe-metabolism kungase kubangele ukusabalala kwamangqamuzana athile omdlavuza.
Uma usebenzisa izithako ze-nicotinamide nucleoside ezifana ne-NMN, ukusebenza kokuzivocavoca kungase kuthinteke.Emagundaneni, amagundane ajovwe ngezithako ze-NAD+ abonise ukusebenza okuncane kakhulu kuneqembu lawo lokulawula.
