Sunan samfur:Galantamine hydrobromide

Wani Suna:Galanthamine hydrobromide; Galantamine HBr; Galanthamine HBr; (4aS,6R,8 a - 4 a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a],3,Hydrobromide

CAS NO:1953-04-4

Ƙayyadaddun bayanai:98.0%

Launi:Farifoda tare da halayyar wari da dandano

Matsayin GMO: GMO Kyauta

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

Ana amfani da Galantamine don maganin cutar Alzheimer mai sauƙi zuwa matsakaici da sauran matsalolin ƙwaƙwalwar ajiya daban-daban, musamman na asalin jijiyoyin jini. Yana da alkaloid da aka samu ta hanyar synthetically ko daga kwararan fitila da furanni na Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) da kuma sauran nau'o'in irin su Narcissus (daffodil)), Leucojum (snowflake) da Lycorisata ciki har da Lycorisata. Red Spider Lily).

Galanthamine na halitta ne wanda aka samo daga lycoris radiate, alkaloids ne na jami'a wanda aka samu daga digon dusar ƙanƙara da nau'ikan da ke da alaƙa. Yana aiki a matsayin mai hana mai hanawa acetylcholinesterase (ACHE), yayin da yake yin rauni akan butyrylcholinesterse (BuChE) .ana amfani da shi wajen magance rikice-rikice na tsarin jijiyoyi na tsakiya kuma ana iya amfani dashi azaman maganin kashe ƙwayoyin tsoka marasa ƙarfi.Galanthamine hydrobromide shine fari zuwa kusan fari foda; mai narkewa cikin ruwa; chloroform mai narkewa, ether da barasa.

Galantamine hydrobromide shine benzazepine wanda aka samo daga kwararan fitila da furanni na narcissus, osmanthus, ko canna. Hakanan mai hana cholinesterase na baka. A matsayin ligand don masu karɓar acetylcholine na nicotinic, an yi amfani da shi sosai don haɓaka aikin neurocognitive. Ayyukansa shine gasa da kuma sake jujjuyawar hana acetylcholinesterase, ta haka yana ƙara haɓakar acetylcholine. Lokacin da aka shiga cikin jini, galantamine hydrobromide yana shiga cikin sassa daban-daban na jiki, ciki har da kwakwalwa. Yana ɗaure ga masu karɓar acetylcholine na nicotinic, yana haifar da canje-canje na daidaituwa da haɓaka sakin acetylcholine. Har ila yau, yana aiki ta hanyar yin gasa tare da sake juyar da tasirin masu hana cholinesterase. Ta hanyar hana cholinesterase, yana hana rushewar acetylcholine, ta haka yana ƙara matakan da tsawon lokaci na wannan neurotransmitter mai ƙarfi. Galantamine na iya inganta ilmantarwa da ƙwaƙwalwar ajiya, hana kumburin kwakwalwa, da kuma kula da manyan matakan neurotransmitters ta hanyar kiyaye mutuncin neurons da synapses.

Aiki:

(1) Anti-cholinesterase.

(2) Ƙarfafawa da hana acetylcholinesterase, daidaita matsayin mai karɓar nicotine intracephalic.

(3) Yana warkar da ciwon inna na jarirai na gaba, sweeny da myasthenia gravis pseudoparalytica, da sauransu.

(4) Inganta aikin ganewa na haske, marasa lafiya marasa lafiya na Alzheimer mai sauƙi, da jinkirta aiwatar da raguwar aikin ƙwayoyin kwakwalwa.

(5) Inganta gudanarwa tsakanin jijiya da tsoka.

Aikace-aikace
1. GalanthamineHydrobromideAn fi amfani dashi a cikin myasthenia gravis, poliovirus quiescent mataki da sequela, har ila yau a cikin polyneuritis, funiculitis da kuma shingen sensorimotor wanda ya haifar da cututtuka na tsarin juyayi ko traumatism;

2. Galanthamine Hydrobromide kuma ana amfani dashi a cikin cutar Alzheimer, yana da babban aiki don lalata da kuma dysmnesia lalacewa ta hanyar kwakwalwar kwayoyin halitta.