inoa huahana:Huina 7P

Inoa ʻē aʻe:Compound7P;2-[(2-methoxyphenyl)[(4-methylphenyl)sulfonyl]amino]-N-(4-methoxy-3-pyridinyl)acetamide ;2-(N-(2-methoxyphenyl)-4- methylphenylsulfonamido)-N-(4-methoxypyridin-3-yl)acetamide

ʻAʻohe CAS:1890208-58-8

Nā kikoʻī: 99.0%

Ka waihoʻoluʻu: ka pauka keʻokeʻo me ka ʻala a me ka ʻono

Kūlana GMO: ʻAʻole GMO

Hoʻopili: ma 25kgs fiber drums

Ka mālama ʻana: E mālama i ka pahu i wehe ʻole ʻia ma kahi maloʻo a maloʻo, e haʻalele i ka mālamalama ikaika

Ola Ola: 24 mahina mai ka lā i hana ʻia

Ua hōʻike ʻia ʻo Compound 7p e hoʻoulu i ka ulu ʻana o GAP-43-positive axons i loko o kahi ʻano holoholona o ka hōʻeha nerve optic, e hōʻike ana i ka hana neurite outgrowth o ka pūhui 7p in vitro e unuhi i ka hoʻoulu ʻana o ka axon regeneration ma Vivo.

I loko o kahi holoholona holoholona o ka ʻeha aʻalolo optic, ua hōʻike ʻia ka 7p pūhui e hoʻoulu i ka ulu ʻana o nā axons maikaʻi gap-43, e hōʻike ana i ka hana in vitro neurite outgrowth o ka hui 7p unuhi i ka hoʻoulu ʻana o ka axon regeneration in vivo.further optimization of compound 7p and elucidation ʻO nā hana e hoʻoulu ai i ka axon regeneration in vivo e hāʻawi i kumu kūpono no nā hana e hiki mai ana e hoʻomaikaʻi i ka mālama ʻana. nā hoʻolālā.

ʻO ka Puʻupuʻu 7P e pili ana i kahi pūhui mea ola i loaʻa nā ʻātoma kalapona ʻehiku. I loko o ka kemika organik, he mea koʻikoʻi ke kalapona no ka mea hiki iā ia ke hana i nā paʻa paʻa me nā ʻātoma ʻē aʻe, me nā ʻātoma kalapona, e hana i nā molekala paʻakikī. Hiki i kēia mau moleke ke loaʻa i nā ʻano waiwai a me nā hana, e hana ana i nā pūhui kalapona i nā poloka kūkulu o ke ola. I nā ʻano holoholona o ka ʻeha nerve optic, ua hōʻike ʻia ka 7p pūhui e hoʻoulu i ka ulu ʻana o GAP-43-positive axons, e hōʻike ana i ka neurite ulu ʻana o ka hui 7p in vitro e unuhi i ka hoʻoulu ʻana o ka axonal regeneration in vivo. ʻO ka pauka 7P he keʻokeʻo a keʻokeʻo keʻokeʻo i hana ʻia ma ke ʻano he hui tandem no ka ʻike ʻana i nā mea hoʻopiʻi antagonist antagonist thromboxane hana ʻelua. ʻO ka ʻoiaʻiʻo, ua hōʻike ka hui 7p i ke koho no ka prostaglandin I2 synthase (PTGIS, CYP8A1) pili i ka thromboxane synthase (CYP5A1). ʻO ka nootropic compound 7P pauka e hoʻoikaika i ka uluʻana o Gap-43-positive axons, a laila e hoʻoulu ai i ka axonal regeneration i ke kino. Hoʻolālā ʻia ʻo Complex 7p kiʻekiʻe e hoʻomaikaʻi i ka hoʻonohonoho ʻana, hoʻomaikaʻi i ke ʻano a kōkua i ke kaua ʻana i ka luhi. Hoʻopaʻa pū ia i ka oxidation o ka lolo a kōkua i ke kaua ʻana i ka pōʻino o ka lolo ma muli o ka inu ʻana i ka waiʻona.

Hana:

ʻO ka hana hou ʻana o Axon ma hope o ka hōʻeha ʻana i loko o ka ʻōnaehana nūnū waena e hoʻopilikia ʻia ma kahi ʻāpana no ka mea inā he emi ʻana o ka makahiki i ka hiki ke ulu axon intrinsic, a ʻo kekahi o nā hoʻolālā e hoʻoulu i ka ulu axon i nā neurons i hōʻeha ʻia e pili ana i ka manipulation pharmacological o nā ala hōʻailona pili. phenotypic cell-based screen of chemical library and structure-activity-guided optimization i hopena i ka ʻike pūhui 7p e paipai ana i ka ulu ʻana o ka neurite o nā neurons moʻomeheu i loaʻa mai ka hippocampus, cerebral cortex, a me retina. i loko o kahi holoholona holoholona o ka optic nerve hōʻeha, hui 7p ua hōʻike ʻia e hoʻoulu i ka ulu ʻana o ka gap-43 axons maikaʻi, e hōʻike ana i ka hana in vitro neurite outgrowth o ka hui 7p unuhi i ka hoʻoulu ʻana o ka axon regeneration in vivo.further optimization of compound 7p and elucidation ʻO nā hana e hoʻoulu ai i ka axon regeneration in vivo e hāʻawi i kumu kūpono no nā hana e hiki mai ana e hoʻomaikaʻi i ka mālama ʻana. nā hoʻolālā.
Noi:

I kēia manawa he lāʻau nootropic akamai e hōʻike ana iā ia iho i kekahi o nā racetams ikaika loa i ka honua nootropic. Hana ʻia mai kahi papa o nā pūhui i kapa ʻia ʻo ka racetams, a me ka hana ʻana ʻaʻole wale i ka acetylcholine akā ʻo nā mea loaʻa GABA hoʻi i loko o ka lolo, hiki i kēia ke hoʻoulu i nā cholinergic a me glutamate receptors o ka cerebral cortex, a he lāʻau racetam kipi ma muli o kona ʻano nui loa. ʻano hana kūikawā. Ke hōʻike nei ʻo Fasoracetam i kēia manawa i nā pōmaikaʻi ma ke ʻano he anti-depressant, ADHD stimulant, a me kahi anxiolytic, ʻo ia hoʻi, e like me ka mea i hōʻike ʻia i loko o nā laboratories ma ka ʻāina, kōkua i ka hoʻokumu ʻana a me ka mālama ʻana i nā hoʻomanaʻo hou.