inoa huahana:Evodiamine

inoa ʻē aʻe:Evodiamine, Isoevodiamine, (+)-Evodiamine, d-Evodiamine,ʻO Fructus Evodiae Extract

ʻAʻohe CAS:518-17-2

ʻIke: 98% Min

Ka waihoʻoluʻu: ʻO ka pauka crystalline melemele māmā

Hoʻopili: ma 25kgs fiber drums

Ka mālama ʻana: E mālama i ka pahu i wehe ʻole ʻia ma kahi maloʻo a maloʻo, e haʻalele i ka mālamalama ikaika

Ola Ola: 24 mahina mai ka lā i hana ʻia

ʻO Evodiamine kahi alkaloid bioactive kū hoʻokahi a me ka mea nui bioactive i loko o ka lāʻau lapaʻau Kina. Loaʻa i nā hua o ka mea kanu Evodia evodia, e ulu nui ana ma Kina a me Korea. ʻO Evodiamine kahi alkaloid bioactive kū hoʻokahi a me ka mea bioactive nui i ka lāʻau lapaʻau Kina. Loaʻa i nā hua o ka mea kanu Evodia evodia, e ulu nui ana ma Kina a me Korea. He waiwai kēia mea kanu i ka ʻokoʻa kemika a ua hoʻohana maʻamau ʻia i ka lāʻau lapaʻau kuʻuna Kina e mālama i nā pilikia olakino like ʻole, e like me nā maʻi digestive, ʻāʻī, a me ka ʻeha. Hana ʻo Evodiamine ma ka huli ʻana i nā ala molekala i loko o ke kino. Ua ʻike ʻia e hoʻoulu i ka hoʻāla ʻana o nā mea hoʻokipa vanillin, kahi mea koʻikoʻi i ka ʻike ʻeha a me ka thermogenesis. Hoʻohui ʻia, ua ʻike ʻia e launa pū me ka serotonin a me ka dopamine receptors, e hōʻike ana he mea hiki ke hoʻonui i ka naʻau.

Hana olaola: ʻO Evodiamine kahi alkaloid i hoʻokaʻawale ʻia mai ka hua o Bentham, nona nā hana olaola like ʻole e like me anti-inflammatory, anti obesity, a me anti-tumor. In vitro: Ua hōʻike ʻo Evodiamine i ka cytotoxicity e kūʻē i nā laina cell cancer ma o ka hoʻoulu ʻana i ka apoptosis. Eia kekahi, he molekele anti-tumor maoli ia e hoʻohana ana i ka hana anti-tumor ma o nā ʻano molekala like ʻole e like me ka caspase dependent a me nā ala ala ʻole, ala sphingomyelin, calcium / JNK hōʻailona, ​​31 PI3K / Akt / caspase, a me Fas -L/. NF – κ B ala hōʻailona 32 [1]. In vivo: Evodiamine inhibits the metabolism of dapoxetine. Ke hoʻohālikelikeʻia me ka pūʻulu mana, ua hoʻonui nuiʻia ka t1 / 2, AUC (0- ∞), a me Tmax pharmacokinetic parameters o dapoxetine i ka hui evodiamine e 63.3%, 44.8%, a me 50.4%. Eia kekahi, ua hoʻemi nui ka evodiamine i ka t1/2 pharmacokinetic parameters a me AUC (0-∞) o demethylated dapoxetine [2]. Kāohi ʻo Evodiamine i ka ulu ʻana o ka maʻi maʻi ma ka subcutaneous H22 xenograft model. Hoʻopau ʻo Evodiamine i ka angiogenesis i hoʻokomo ʻia i ka VEGF i loko o vivo.

In vitro: Hōʻike ʻo Evodiamine i ka cytotoxicity e kūʻē i nā laina cell cancer ma o ka hoʻoulu ʻana i ka apoptosis. Eia kekahi, he mole mole anti-tumor maoli ia e hoʻohana ana i ka hana anti-tumor ma o nā ʻano molekala like ʻole e like me ka caspase dependent a me nā ala ala ʻole, ala sphingomyelin, calcium / JNK hōʻailona, ​​31 PI3K / Akt / caspase, a me Fas -L/. NF – κ B ala hōʻailona 32 [1].

In vivo: Evodiamine inhibits the metabolism of dapoxetine. Ke hoʻohālikelikeʻia me ka pūʻulu mana, ua hoʻonui nuiʻia ka t1 / 2, AUC (0- ∞), a me Tmax pharmacokinetic parameters o dapoxetine i ka hui evodiamine e 63.3%, 44.8%, a me 50.4%. Eia kekahi, ua hoʻemi nui ka evodiamine i ka t1/2 pharmacokinetic parameters a me AUC (0-∞) o demethylated dapoxetine [2]. Kāohi ʻo Evodiamine i ka ulu ʻana o ka maʻi maʻi ma ka subcutaneous H22 xenograft model. Hoʻopau ʻo Evodiamine i ka angiogenesis i hoʻokomo ʻia i ka VEGF i loko o vivo.

HANA:

Loaʻa nā hana anti-inflammatory, anti-tumor, a me hypoglycemic i kekahi mau hopena therapeutic i ka mālama ʻana i ka dementia kahiko a me ka hahau. ʻO ka pono lapaʻau o kēia huahana ka hana ʻana i nā lāʻau lapaʻau no ka diuretics a me ka hou.

1. Hoʻohana ʻia ʻo Evodia extract e mālama i nā hōʻailona o ka ʻeha o ka ʻōpū. ʻO kēia mau mea e pili ana i ka nausea, ka luaʻi, a me ka maʻi maʻi. Ua ʻōlelo ʻia he mea maikaʻi loa ia i ka mālama ʻana i ka maʻi maʻi kakahiaka.

2. Hoʻohana ʻia ʻo Evodia no ka hoʻoulu ʻana i ka ʻai a me ka mālama ʻana i nā hōʻailona ʻōpū e pili ana me ka makemake ʻole i ka meaʻai.

3. Evodia extract no hoi he anti-inflammatory, anti-tumor, anti-viral, astringent, a me diuretic waiwai.

4. ʻO Evodiamine me ka analgesia, hoʻohaʻahaʻa i ke koko a me ka piʻi ʻana o ka mahana o ke kino a me nā hopena pharmacological ʻē aʻe.

5. Loaʻa ka ʻōpū o ka Evodiamine, hoʻōki i ka hoʻihoʻi ʻana, ka hopena oxyrygmia a me ka hopena diuretic.

6.Evodiamine i ka ikaika inhibitory hopena ma li; a me ka hopena insecticidal nui ma ka ascarissuum;

Hiki i ka Evodiamine ke ho'ēmi i ka'ōpū a hoʻonui i ke kaomi.

8. Ma waho aʻe, he hopena maikaʻi ka evodiamine i ka maʻi o Alzheimer a me ka hahau.

Noi: