inoa huahana:ʻO Galantamine Hydrobromide

inoa ʻē aʻe:Galanthamine hydrobromide;Galantamine HBr; Galanthamine HBr;(4aS,6R,8aS)-4a,5,9,10,11,12-hexahydro-3-methoxy-11-methyl-6H-Benzofuro[3a,3,Hydrobromide

CAS NO：1953-04-4

Nā kikoʻī:98.0%

kala kala:Keʻokeʻopauda me ke ʻala a me ka ʻono

Kūlana GMO: ʻAʻole GMO

Hoʻopili: ma 25kgs fiber drums

Ka mālama ʻana: E mālama i ka pahu i wehe ʻole ʻia ma kahi maloʻo a maloʻo, e haʻalele i ka mālamalama ikaika

Ola Ola: 24 mahina mai ka lā i hana ʻia

Hoʻohana ʻia ʻo Galantamine no ka mālama ʻana i ka maʻi ʻeha a me ka haʻahaʻa o ka maʻi Alzheimer a me nā hemahema hoʻomanaʻo ʻē aʻe, ʻo ia hoʻi nā mea o ke kumu vascular. He alkaloid ia i kiʻi ʻia a i ʻole mai nā ʻōpuʻu a me nā pua o Galanthus Caucasicus (Caucasian snowdrop, Voronov's snowdrop), Galanthus woronowii (Amaryllidaceae) a me nā genera pili e like me Narcissus (daffodil)), Leucojum (snowflake) a me Lycoris (Lycoris radiatata). Lily Punawelewele).

Lawe ʻia ʻo Galanthamine mai ka lycoris radiate, he alkaloid tertiary i loaʻa mai ka hāʻule hau a me nā ʻano pili pili. Hoʻohana ʻia ia ma ke ʻano he mea hoʻokūkū hoʻokūkū acetylcholinesterase (ACHE) inhibitor, ʻoiai ʻoi aku ka nāwaliwali o ka butyrylcholinesterse (BuChE). keokeo a aneane keokeo pauda; hiki ke hoʻoheheʻe ʻia i ka wai; chloroform insoluble, etera a me ka waiʻona .

ʻO Galantamine hydrobromide he benzazepine i loaʻa mai nā ʻōpala a me nā pua o ka narcissus, osmanthus, a i ʻole canna. ʻO ia hoʻi he mea hoʻopaneʻe cholinesterase waha. Ma ke ʻano he ligand no ka nicotinic acetylcholine receptors, ua hoʻohana nui ʻia e hoʻonui i ka hana neurocognitive. ʻO kāna hana ka hoʻokūkū hoʻokūkū a hoʻihoʻi hou i ka acetylcholinesterase, a laila e hoʻonui ai i ka ʻike o ka acetylcholine. Ke komo ʻia i loko o ke kahe koko, hoʻopili koke ʻia ka galantamine hydrobromide i nā ʻāpana like ʻole o ke kino, me ka lolo. Hoʻopili ia i nā mea loaʻa acetylcholine nicotinic, e hoʻololi ana i ka conformational a me ka hoʻonui ʻana i ka acetylcholine. Hoʻohana pū ia me ka hoʻokūkū a me ka hoʻohuli ʻana i nā hopena o ka cholinesterase inhibitors. Ma ke kāohi ʻana i ka cholinesterase, pale ia i ka haki ʻana o ka acetylcholine, ma laila e hoʻonui ai i nā pae a me ka lōʻihi o kēia neurotransmitter ikaika. Hiki i ka Galantamine ke hoʻomaikaʻi i ke aʻo ʻana a me ka hoʻomanaʻo, pale i ka ʻeha o ka lolo, a mālama i nā kiʻekiʻe kiʻekiʻe o nā neurotransmitters ma ka mālama ʻana i ka pono o nā neurons a me nā synapses.

Hana:

(1) Anti-cholinesterase .

(2) Hoʻoulu a kāohi i ka acetylcholinesterase, hoʻoponopono i ke kūlana o ka nikotine intracephalic.

(3) Ho'ōla i ka maʻi maʻi pēpē pēpē, sweeny a me myasthenia gravis pseudoparalytica, etc.

(4) E hoʻomaikaʻi i ka hana ʻike o ka māmā, nā maʻi maʻi Alzheimer ʻoluʻolu nui, a hoʻopaneʻe i ke kaʻina hana o ka emi ʻana o nā pūnaʻi lolo.

(5) E hoʻomaikaʻi i ka hana ma waena o ke aʻalolo a me ka ʻiʻo.

Palapala noi
1. GalanthamineHydrobromideHoʻohana nui ʻia i ka myasthenia gravis, ka poliovirus quiescent stage a me ka sequela, a me ka polyneuritis, funiculitis a me ka pale sensorimotor i hoʻokumu ʻia e ka maʻi ʻōnaehana nerve a i ʻole traumatism;

2. Hoʻohana pū ʻia ʻo Galanthamine Hydrobromide i ka maʻi o Alzheimer, ʻo ia ka hana nui no ka dement a me ka dysmnesia ma muli o ka pōʻino o ka lolo.