ʻApigenin Paʻa Paʻa

No ka hana ʻana i nā pōmaikaʻi hou aʻe no ka poʻe kūʻai aku ʻo kā mākou ʻoihana ʻoihana;ʻO ka mea kūʻai e ulu nei kā mākou hana hana no ka MOQ haʻahaʻa no Kina ke kumu kūʻai nui o nā mea kanuʻO Apigenin PaukaMālama i nā ʻAha Koko Ola Ola, Hoʻokipa mākou i nā mea kūʻai aku, nā hui ʻoihana ʻoihana a me nā hoaaloha mai nā wahi āpau mai ke kaiapuni e kamaʻilio me mākou a e ʻimi i ka hui ʻana no ka loaʻa ʻana o kekahi.
No ka hana ʻana i nā pōmaikaʻi hou aʻe no ka poʻe kūʻai aku ʻo kā mākou ʻoihana ʻoihana;ʻO ka ulu ʻana o ka mea kūʻai aku kā mākou hana hanaʻO Apigenin Pauka, Kina Apigenin, no ka mea, ke hoʻomau nei kā mākou hui i ka manaʻo hoʻokele o "Survival by Quality, Development by Service, Benefit by Reputation" .Hoʻomaopopo piha mākou i ke kūlana hōʻaiʻē maikaʻi, nā waiwai kiʻekiʻe, ke kumukūʻai kūpono a me nā lawelawe akamai ke kumu e koho ai nā mea kūʻai iā mākou e lilo i hoa ʻoihana lōʻihi.
ʻO Apigenin, ma keʻano he bioflavonoid iʻikeʻia, ua hōʻikeʻia e hōʻike i nā hana olaola likeʻole, e like me ka antioxidant, anti-inflammatory, antitumor, ant-genotoxic, anti-allergic, neuroprotective, cardioprotective, and antimicrobial. celery (Apium graveolens), he mea kanu marsh ma ka ʻohana Apiaceae i mahi ʻia ma ke ʻano he mea kanu mai ka wā kahiko.ʻO ApigeninʻO ka meaʻai nui loa i unuhiʻia i ka celery, aia ka 108 mg apigenin i ka kg.ʻO Apigenin kekahi o nā flavonoids meaʻai maʻamau, i loaʻa nui i nā huaʻai, nā mea kanu, a me nā lāʻau lapaʻau.Hoʻohana ia i nā hana physiological like ʻole, e like me antioxidant, potent anti-inflammatory, antiviral activities, antibacterial a me ke kahe koko.

Inoa mea kūʻai:He 98% ka wehe ʻana o ka lau Celery Apigenin

Inoa Latina: Apium graveolens L.

No CAS: 520-36-5

Māhele Mea kanu i hoʻohana ʻia:Leaf

Mea komo: Apigenin

ʻIke: Apigenin 98.0% na HPLC

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Ka hopena anti-tumor

He kuleana koʻikoʻi ka Apigenin i ka pale ʻana i ka maʻi maʻi ma o ka hoʻoulu ʻana i ka apoptosis i nā laina kelepona like ʻole.

Ka maʻi 'ovarian:

Ua ʻike ʻia kekahi mau noiʻi e hiki i ka apigenin ke kāohi i ka ulu ʻana, ka hoʻonui ʻana, a me ka hoʻololi ʻana o ka ca-ov3 (ke kanaka ovarian cancer cell);hoʻoulu ʻo ia i ka apoptosis o ca-ov3 ma o ka mālama ʻana i nā maʻi maʻi maʻi i ka pae G2/M.Pili ka hopena i ka manawa a me ka nui.

ʻO ka maʻi maʻi pancreatic:

Hiki i ka Apigenin ke pale i ka hoʻonui ʻana o nā maʻi maʻi pancreatic.Pōloli ʻo Apigenin i ke koko ma o ka hoʻemi ʻana i ke kumu o ka glucose, ʻo ia ka meaʻai e ola ai nā maʻi kanesa.Ma waho aʻe, hiki i ka Apigenin ke hoʻomaikaʻi i ka maikaʻi o ka lāʻau chemotherapy- gemcitabine.

Kemo-naʻi

Ua ʻike ʻia ʻo ka apigenin i loko o ka haʻahaʻa haʻahaʻa he hopena cytotoxic haʻahaʻa a ʻaʻole hiki ke hoʻoulu i ka maʻi leukemia myeloid acute kanaka (hl-60) i ka apoptosis pono.Eia naʻe, hiki i ka apigenin ke hoʻonui i ka hopena o ka cisplatin (DDP) ma ka hl-60 cell proliferation me ka hui pū me nā manaʻo likeʻole o DDP.No laila hiki i ka Apigenin ke loaʻa ka hopena chemotherapy-sensitization ma hl-60;Hiki i nā haʻahaʻa haʻahaʻa o apigenin ke hoʻemi i ke kūʻē ʻana o nā cell hl-60 i ka apoptosis i hoʻokomo ʻia i ka chemotherapy, pili paha i ka hoʻoponopono iho o NF-κB a me BCL-2.(NF-KB he ʻano protein complex e hoʻomalu ana i ka palapala DNA, ka hana ʻana o nā cytokines a me ke ola o nā cell; Hoʻopili ʻia ʻo BCL-2 i ke kino ma o ka BCL2 gene, ʻo ia ka lālā kumu o ka ʻohana protein regulatory BCL-2. hiki ke hoʻoponopono i ka make cell)

Ka mālama ʻana i ke ake

Hiki i ka Apigenin ke hōʻemi i ka ʻeha o ka ate i hoʻoulu ʻia e ka ischemia-reperfusion ma o ka antagonizing lipid peroxidation a me ka scavenging free radical.

Hiki i ka Apigenin ke hōʻemi i ka ʻeha o ka ate ma muli o ke koʻikoʻi oxidative ma muli o kāna mau hana antioxidant a me nā hana anti-inflammatory.

Ua hōʻike nā hoʻokolohua lāʻau lapaʻau he hopena palekana ko apigenin i ka ʻeha o ka ate / hepatocyte i hoʻokomo ʻia i ka waiʻona, a ʻo kāna ʻano kumu mua e pili ana i ka pale ʻana i ka ʻōlelo CYP2E1 i loko o ke ake / hepatocyte.

Kāohi i ka osteoporosis

Kāohi ʻo Apigenin i ka osteoblastogenesis, osteoclastogenesis, a pale pū i ka nalo iwi.

Mālama ʻo Apigenin i ka ʻiʻo iwi ma ka hōʻemi ʻana i ka nalowale o ka iwi ma ke kino.

ʻO kekahi mau haʻawina e pili ana i ka MC3T3-E1, he osteoblast precursor cell line i loaʻa mai Mus musculus (mouse) calvaria, ua ʻike ʻo apigenin hiki ke kāohi i ka TNF-α, IFN-γ, a laila hoʻoulu i ka huna ʻana o kekahi mau cytokines e hoʻoikaika i ka hoʻokumu osteoclast.

Apigenin no hoi i keakea i ka differentiation o 3T3-L1 adipose precursor pūnaewele i adipocytes ikaika, no laila, inhibiting ka differentiation attendant inhibition adipocyte differentiation-induced IL-6, MCP-1, lectin huahana.

Hoʻopili ʻo Apigenin i ka hoʻokaʻawale ʻana o nā osteoclast mai RAW264.7 laina kelepona a laila keʻakeʻa i ka hoʻokumu ʻana o nā osteoclast multinucleated.Hiki iā ia ke hoʻoulu i ka apoptosis osteoclast a keʻakeʻa i ka resorption iwi.

Ka hana anti-inflammatory a me ka anti-oxidant

Hoʻopaʻa ʻo Apigenin i ke kaʻina hana ʻona, hoʻonui i nā pae IL-10 a hoʻomaʻamaʻa i nā ʻāpana koʻikoʻi oxidative.

Kāohi ʻo Apigenin i nā cytokine pro-inflammatory a hoʻoulu i ka hana anti-inflammatory cytokine.

Ke hōʻike nei kekahi mau palapala e hoʻopau ka apigenin i ka ʻāʻī o ka ʻiʻo i hoʻoulu ʻia e ke koʻikoʻi oxidative i loko o nā ʻiʻo ma o ka hoʻololi ʻana i nā hōʻailona koʻikoʻi oxidative, interleukins, nā hōʻailona enzyme koko, a me ka hōʻike ʻana o kekahi mau enzyme pili.

Hoʻoponopono i ka endocrine

Hiki i ka Apigenin ke hoʻoponopono i ke kō koko, mālama i ka lawaʻole o ka thyroid a mālama i ka lipid peroxidation. 6-Pase).

Ua hoʻohuli ʻo Apigenin i nā hopena o ka hoʻonui ʻana i ka cholesterol serum, hoʻonui i ka ate lipid peroxidation (LPO) a hoʻemi i nā hana o nā antioxidants e like me catalase (CAT) a me superoxide dismutase (SOD) i nā holoholona alloxan-induced.

I nā holoholona me ke kō koko maʻamau, hiki i ka apigenin ke hoʻemi i ka cholesterol serum a me ka lipid peroxidation ate, a hoʻonui i ka hana o nā antioxidants i nā cell.

Nā waiwai pharmacological o apigenin

Ua hoʻopili nui ʻia ʻo Apigenin i nā makahiki i hala iho nei, ma ke ʻano he mea hoʻolaha olakino maikaʻi ma muli o ka haʻahaʻa o ka ʻawaʻawa a me kona hopena olakino i nā maʻi maʻi maʻi maʻamau, i hoʻohālikelike ʻia me nā flavonoids e pili ana i ke ʻano.Aia ka nui o nā hōʻike noiʻi e hōʻike ana i ka apigenin he mea lapaʻau nui no nā maʻi he nui

Hana:

-Kaohi i ka ulu ana o na ma'i ma'i.

-E hoʻohaʻahaʻa i ke koko

- Mālama i ka ʻōnaehana cardiovascular

- Kōkua i ka hiamoe, hoʻomaha i nā aʻalolo, hoʻopau i ka huhū

-E pale i ka mumū

-E pale i ka osteoporosis

- Ka hopena diuretic.

-Kāʻe i ka platelet aggregation.

Noi:

-Mahele lāʻau lapaʻau, kahua mālama ola kino