Inoa mea kūʻai:Stearoyl Vanillylamide（SVA）
Inoa ʻē aʻe: C18-VA, N-Vanillyloctadecanamide, Capsaicin AnalogCAS Nhelu:58493-50-8
Puna Hua:Piper Longum Linn
ʻIke: 98%
Laʻana manuahi: Loaʻa
ʻAno: keʻokeʻo i ka pauka keʻokeʻo
Pono: Anti-cancer, anti-aging, senolytic
Ke ola papa: 2 makahiki
ʻO Stearoyl vanillylamide kekahi o nā analog capsaicin kaulana loa a he capsaicin analog maoli nō i loaʻa i nā ʻano pepa ʻulaʻula.ʻO ka Capsaicin ke kumu o ka wela a me ka wela o ka pepa.ʻAʻole like me nā ʻano capsaicin ʻē aʻe i loko o ka ʻāpana like, ʻokoʻa ʻo Stearoyl vanillylamide no ka mea he non-steroidal, ʻo ia hoʻi ʻaʻole ia e hoʻopuka i ka hopena "spicy" a i ʻole nā hopena hoʻonāukiuki o ka capsaicin.
ʻO ka mea maʻamau, e like me nā analog capsaicin ʻē aʻe, hana kēia hui ma ka hoʻonui ʻana i ka hoʻokuʻu ʻana o ka epinephrine a me nā norepinephrine.Pono kēia mau hormones e hoʻāla i nā ʻano like ʻole o ke kino aloha e like me ka metabolism.No laila, ʻo ka stearoyl vanillylamide ka hopena i ka ʻā ʻana o ka momona ʻeleʻele i loko o ka ʻiʻo adipose a i ʻole ke kino subcutaneous.
He aha nā pōmaikaʻi o ka hoʻohana ʻana iā Stearoyl Vanillylamide?ʻO ka hoʻokomo ʻana i ka stearic acid amide he mau pono i ka hoʻomākaukau ʻana i nā mea hoʻohui olakino.Ke hoʻomau nei nā haʻawina he nui, ke kakali nei ka poʻe ʻepekema i ka ʻike hou aku i nā pono o ka hoʻohana ʻana i kēia pūhui.Eia kekahi o nā pono i ʻike ʻia no ka hoʻohana ʻana iā Stearoyl vanillylamide:
Hoʻopau maikaʻi ia i ka momona o ka ʻōpū
Hana ʻo Stearoyl vanillylamide ma ke ʻano he capsaicin hoʻonāukiuki ʻole hiki ke hoʻoulu i ka ʻiʻo adipose brown a i ʻole ka momona ʻeleʻele (ʻike nui ʻia ka momona i loko o ka mitochondria a hana i ka wela i ke kino).Loaʻa ka momona ma nā wahi āpau o ke kino, me nā lima, nā ʻūhā, nā ʻōpū a me nā ʻiʻo gluteal.ʻOiai hiki i ka hapa nui o nā kānaka ke hoʻopau koke i ka momona ma nā wahi ʻē aʻe, ʻo ka puhi ʻana i ka momona o ka ʻōpū i manaʻo ʻia he kaumaha maoli.Ua hōʻike nā haʻawina i ka lawe ʻana i ka Stearoyl vanillylamide hiki ke kōkua i ka wāwahi ʻana i nā momona i loaʻa i loko o ka ʻōpū.Loaʻa kēia ma ka hoʻoulu ʻana iā TRPV1, kahi enzyme e pale ai i ka hana momona o ka ʻōpū a me ka hoʻokumu ʻana i ka momona.Me ka capsaicin, ua manaʻo ʻia ʻo Stearoyl vanillylamide ʻo ia kekahi o nā mea hana e hoʻolalelale a hoʻāla i ka TRPV1 (transient receptor potential vanilloid) aia i loko o ka membrane plasma (koe wale nō nā ligands endogenous, nā mea hoʻomohala inflammatory a me nā stimuli koho ʻole).He kuleana no ka hoʻopili ʻana i kahi protein membrane integral ma ke ʻano he kaila ion.Ke hoʻoikaika ponoʻiaʻo TRPV1 ma nā fiber sensory a me nā pūnaewele non-neuronal, e hopena ia i ka hoʻokomoʻana o ka calcium a me ka sodium, pono ia no ka depolarization membrane (ka hoʻololi polarity; mai ka maikaʻiʻole i ka maikaʻi, e alakaʻi ana i nā hopena Positive maikaʻi) Hana pūnaewele a me kāna. kamaʻilio.
Hoʻopau maikaʻi ia i ka momona o ka ʻōpū
Hana ʻo Stearoyl vanillylamide ma ke ʻano he capsaicin hoʻonāukiuki ʻole hiki ke hoʻoulu i ka ʻiʻo adipose brown a i ʻole ka momona ʻeleʻele (ʻike nui ʻia ka momona i loko o ka mitochondria a hana i ka wela i ke kino).Loaʻa ka momona ma nā wahi āpau o ke kino, me nā lima, nā ʻūhā, nā ʻōpū a me nā ʻiʻo gluteal.ʻOiai hiki i ka hapa nui o nā kānaka ke hoʻopau koke i ka momona ma nā wahi ʻē aʻe, ʻo ka puhi ʻana i ka momona o ka ʻōpū i manaʻo ʻia he kaumaha maoli.Ua hōʻike nā haʻawina i ka lawe ʻana i ka Stearoyl vanillylamide hiki ke kōkua i ka wāwahi ʻana i nā momona i loaʻa i loko o ka ʻōpū.Loaʻa kēia ma ka hoʻoulu ʻana iā TRPV1, kahi enzyme e pale ai i ka hana momona o ka ʻōpū a me ka hoʻokumu ʻana i ka momona.Me ka capsaicin, ua manaʻo ʻia ʻo Stearoyl vanillylamide ʻo ia kekahi o nā mea hana e hoʻolalelale a hoʻāla i ka TRPV1 (transient receptor potential vanilloid) aia i loko o ka membrane plasma (koe wale nō nā ligands endogenous, nā mea hoʻomohala inflammatory a me nā stimuli koho ʻole).He kuleana no ka hoʻopili ʻana i kahi protein membrane integral ma ke ʻano he kaila ion.Ke hoʻoikaika ponoʻiaʻo TRPV1 ma nā fiber sensory a me nā pūnaewele non-neuronal, e hopena ia i ka hoʻokomoʻana o ka calcium a me ka sodium, pono ia no ka depolarization membrane (ka hoʻololi polarity; mai ka maikaʻiʻole i ka maikaʻi, e alakaʻi ana i nā hopena Positive maikaʻi) Hana pūnaewele a me kāna. kamaʻilio.
