Dihydromyricetin 98%

Dihydromyricetin, nke a makwaara dị ka Ampelopsin, bụ flavanonol, ụdị flavonoid.A na-achọta ya na ụdị Amplopsis japonica, megalophylla, na grossedentata;Cercidiphyllum japonicum;Hovenia dulcis;Rhododendron cinnabarinum;ụfọdụ ụdị Pinus;na ụfọdụ ụdị Cedrus, yana Salix sachalinensis.

A na-eji Hovenia dulcis na ọgwụ ọdịnala ndị China na-agwọ ahụ ọkụ, ọrịa parasitic, dị ka ihe na-egbu egbu, na ọgwụgwọ nke ọrịa imeju, yana ọgwụgwọ nkwụsịtụ.E mepụtara ụzọ iji wepụ ampelopsin na ya na nnukwu akpịrịkpa.

N'ime ụzọ nke iri isii ndị ọrịa nwere ọrịa imeju abụba dihydromyricetin na-emeziwanye glucose na lipid metabolism ma mee ihe mgbochi mkpali nke bara uru.Vine tii wepụ dihydromyricetin ntụ ntụ na-amịpụta site na stems na epupụta nke Ampelopsis Grossedentata (a na-akpọkarị tii vine).Dihydromyricetin nwere antioxidant, mmanya na-egbu egbu na-egbu egbu, mgbochi mkpali na mgbochi ọrịa cancer, ọ na-enye aka maka ikpochapụ radicals n'efu, na-echebe ọrụ imeju na ịhazi shuga ọbara na abụba ọbara.Vine tii wepụ dihydromyricetin bụ tumadi eji na imeju nchebe na mmanya mgbochi-egbu egbu Mmeju na akpụkpọ nlekọta ngwaahịa.Vine tii, a na-akpọkwa dị ka Cany tii ma ọ bụ Ampelopsin.Dihydromyricetin na-amịpụtara si na-eto eto azuokokoosisi na akwukwo nke Cany tii (Ampelopsin) Researches show show. karịa vine tii nwere ike inyeaka mkpali, ngwakọta ụkwara na antitussives, ọ nwekwara ike inhibitory mmetụta na nkịtị nje bacteria nwere ike dị na food. Ụfọdụ flavonoids, ihe atụ Ampelopsin na Dihydromyricetin, bụ isi ifịk ifịk Efrata na osisi vine tii, nke nwere fọrọ nke nta ka otu MIC. na MBC atụnyere berberine, ma nwee nnukwu ọrụ mkpochapụ radical dị iche iche n'etiti 73.3 ~ 91.5%.Ọ nwekwara ike ibelata mmebi oxidative n'ime ahụ, mgbochi ịka nká, belata nrụrụ na anụ ahụ necrosis nke imeju anụmanụ. .N'okwu a, a na-ewere Dihydromyricetin dị ka ngwaahịa dị mma maka ịkwalite ọrụ SOD, na-echebe imeju na iwepu inebriation.
Dihydromyricetin abanyela n'ule ụlọ ọgwụ dị ka klas nke ọgwụ ọhụrụ mgbe onye nyocha Dihydromyricetin nwetara nnukwu ọganihu n'ọhịa nke mgbochi ọrịa leukemia na ọgwụ nke ọrịa kansa Nasopharyngeal.

Aha ngwaahịa: Dihydromyricetin 98%

Nkọwapụta:98% nke HPLC

Isi mmalite nke Botanic: Hovenia dulcis

Nọmba CAS: 200-001-8

Akụkụ osisi eji: ogbugbo

Agba: ọcha ezi ntụ ntụ nwere àgwà isi na uto

Ọnọdụ GMO: GMO efu

Mbukota: na 25kgs fiber drum

Nchekwa: Debe akpa na-emegheghị n'ebe dị jụụ, ebe kpọrọ nkụ, zere ọkụ siri ike

Ndụ shelf: ọnwa 24 site na ụbọchị mmepụta

Ihe ka ọtụtụ ná ndị na-aṅụ mmanya na-aba n’anya na-ama ihe mgbu na-enwe: isi ọwụwa, isi ọwụwa, ike ọgwụgwụ, ọgbụgbọ, ahụ erughị ala afọ, ụra, ọsụsọ, akpịrị ịkpọ nkụ, na ịma ihe.

Nke a bụ ihe mgbakwunye nri nke nwere ike belata agụụ gị nke ukwuu, ọ bụghị naanị ime ka ị nwee ọmarịcha mmanya, vodka, rum na whiskey mana atụla egwu ahụ erughị ala nke ịṅụbiga mmanya ókè na-akpata.

Nke a bụ Dihydromyricetin ntụ ntụ (DHM), onyinye sitere n'okike sitere n'osisi ọwụwa anyanwụ oge ochie nke tii vine.

Kedu ihe bụ dihydromyricetin (DHM)?

Dihydromyricetin, nke a makwaara dị ka glucose agwọ, bụ flavonoid pụrụ icheewepụtara na tii vinema ọ bụ Hovenia Dulcis.

Usoro nhazi DHM:

Njirimara anụ ahụ na kemịkal DHM:

Crystal agịga na-acha ọcha, soluble na mmiri ọkụ, ethanol na-ekpo ọkụ, na acetone, bụkwa nke na-agbaze na ethanol na methanol, ma ọ na-esiri ike na ethyl acetate, nke na-adịghị edozi na chloroform, petroleum ether.Ọmụmụ ihe ọmụmụ microherb ekwuola na dihydromyricetin nwere ezigbo nkwụsi ike nke thermal, mana oxidation na-apụghị ịgbagha agbagha na-eme mgbe dihydromyricetin karịrị 100 Celsius.DHM kwụsiri ike n'okpuru ọnọdụ na-anọpụ iche na acidic.

Ihe ndị a nwere ọtụtụ mmetụta pụrụ iche dị ka scavenging free radicals, mgbochi oxidation, mgbochi thrombosis, mgbochi tumor, mgbochi mkpali, na na.A na-akpọ ya ihe pụrụ iche n'ihi na ọ nwere njirimara ndị a na mgbakwunye na njirimara zuru oke nke flavonoids:

1. Flavonoids juru ebe niile bụ nke a na-adịghị ahụkebe na mmiri, na-agbaze na ethanol (mmanya), na DHM na-agbaze ngwa ngwa n'ime mmiri ọkụ, nke pụtara na DHM na tii vine nwere ike iji mmiri esi mmiri gbanye ma na-arụ ọrụ nke ọma;
2. Na mgbakwunye na ọrụ nke flavonoids n'ozuzu, dihydromyricetin nwere ọrụ nke ịkwụsị ịṅụbiga mmanya ókè, igbochi imeju aṅụrụma, na imeju abụba abụba, na-egbochi mmebi nke mkpụrụ ndụ imeju, na ibelata ọrịa cancer imeju;ọ bụ ngwaahịa kwesịrị ekwesị maka ichebe imeju na ichekwa imeju na agụụ.
3. Dihydromyricetin nwere obere molekul (320), nke dị mfe ịgafe ihe mgbochi ụbụrụ ọbara ma nwee mmalite ngwa ngwa.

Gịnị bụ vine tii wepụ?

Tii vine, nke a na-akpọkarị tii berry, bụ osisi vaịn ọhịa nke nwere ụdị Vitis.Ọ bụghị naanị ihe ọṅụṅụ na-acha akwụkwọ ndụ akwụkwọ ndụ dị ọcha kamakwa tii nwere ọgwụ nwere ike.Ọ bara ụba na flavonoids, amino acids, vitamin na ihe ndị dị mkpa.Ọ nwere ọrụ nke ime ka arịa ọbara dị nro, sterilizing na mgbochi mkpali, na ịṅụ mmanya ogologo oge nwere ike iwepụ ahụike nke ahụ mmadụ.Ọ bụla akụkọ ihe mere eme nke ịṅụ mmanya n'obodo kemgbe ọtụtụ puku afọ, a na-akọkwa ya kemgbe ọtụtụ narị afọ.Ruo ọtụtụ puku afọ, ọ bụ ọkacha mmasị nke ndị omeiwu bụ ndị isi, ọ bụkwa obi onye ọrụ ubi.

Dị ka ihe oriri na ndị ọkachamara tii si kwuo, tii vine bara ụba na phytonutrients.N'ime ha, dihydromyricetin nwere pụtara ikpochapụ okpomọkụ na detoxification, dilating akpịrị, mgbochi nje na mgbochi mkpali, mgbochi influenza nje ịba ọcha n'anya B ma na-enyere aka "atọ elu" mgbochi na ọgwụgwọ nke ọrịa obi na cerebrovascular.

Vine tii wepụ VS Hovenia Dulcis wepụ

Hovenia Dulcis abụghị isi iyi nke dihydromyricetin ebe ọ bụ na ọ dị ntakịrị na ọdịnaya yana ọnụ ahịa dị elu.Vine tii bụ nhọrọ kacha mma.

Kedu ka DHM si ewepụ mmanya na mmanya?

DHM nwere ike ime ka ahụ gị sikwuo ike imebi mmanya na-aba n'anya, yabụ ị gaghị enwe ụtụtụ- ụfụ na ụra mgbe i tetara.

Kedu ihe jikọrọ mmanya na-aba n'anya na mmetụta gị nke ụbọchị nke abụọ?

Otu ụlọ ọrụ aha ya bụ "The National Institute of Alcohol Abuse and Alcoholism" nwere ọtụtụ ajụjụ akpọrọ < Mmanya Metabolism: Mmelite>.

Ọmụmụ ihe ahụ na-akọwa usoro izizi nke mmebi mmanya.Anyị nọ ebe a iji chịkọta akụkụ ndị dị mkpa maka gị.

Enzymes abụọ - mmanya dehydrogenase (ADH) na acetaldehyde dehydrogenase (ALDH) - na-enyere ahụ gị aka ịkwụsị mmanya.

Mgbe mbụ ị malitere ịṅụ mmanya, ADH na-agbaji mmanya na-aba n'anya ka ọ bụrụ acetaldehyde, ihe na-egbu egbu na carcinogenic.

Na-esote, ALDH gakwara n'ihu metabolize acetaldehyde n'ime ngwaahịa acid a na-akpọ acetate, nke a na-agbajikwa n'ime mmiri wee wepụ ya n'ahụ gị n'enweghị nsogbu.

Ya mere, gịnị kpatara na ị naghị enwe ahụ iru ala n'ụtụtụ mgbe ị ṅụsịrị mmanya n'abalị?

Mgbe ị na-aṅụ ihe karịrị ọnụ ọgụgụ nke imeju nwere ike imebi, nsị nke mmanya ndị a na-akpata ga-agbakọta ma tinye nnukwu nrụgide n'ahụ gị.

Ogologo ihe ndị a na-egbu egbu dị n'ime ahụ gị, otú ahụ ka ị ga-enwe mmetụta n'echi ya tupu metabolism na mkpochapụ dị mma.

N'ikwu ya n'ụzọ ọzọ, a na-ekpughe ihe ndị na-egbu egbu ogologo oge n'ime ahụ gị ma nwee ike ịbawanye nsonazụ nke ịṅụ mmanya.

DHM na-abịa napụta!

Flavonoid a dị ike na-enyere aka chebe imeju (na mmetụta gị n'echi ya) site n'ịgbalite metabolism nke mmanya.

Olee otú anyị si mara?

Nnyocha e mere egosiwo na vine tii wepụ DHM nwere ike ime ka ọrụ ADH na ALDH dịkwuo elu n'ime imeju, na-ekwe ka ahụ nwee ike metabolize ma wepụ mmanya na nsị ngwa ngwa.

Mgbe ahụ, ị ​​na-eteta wee nwee ume ọhụrụ na njikere maka ụbọchị ọhụrụ!

Kedu ka DHM na mmanya si emetụta ụbụrụ?

Mmanya na-enwe mmetụta dị ukwuu n'ụbụrụ.

Nkwụsị nke mbụ na-emebi nguzozi siri ike n'etiti neurotransmitters abụọ:

gamma-aminobutyric acid(GABA) na glutamate.

Ndụmọdụ:

Kedu ihe bụ GABA?

GABA bụ amino acid na-abụghị protein na-apụta n'ọdịdị nke bụ ihe dị mkpa na-egbochi neurotransmitter na sistemụ ụjọ mammalian.Ọ na-arụ ọrụ dị mkpa na ụbụrụ ụbụrụ mmadụ, hippocampus, thalamus, basal ganglia na cerebellum, ma nwee mmetụta na-achịkwa ọrụ dị iche iche nke ahụ.Ya bụ, mgbe ahụ erughị eru GABA, ọ ga-emepụta nchegbu, nchegbu, ike ọgwụgwụ, nchegbu na mmetụta ndị ọzọ.

Dị ka ihe na-egbochi neurotransmitter, GABA nwere ike igbochi oke nzuzo nke neurotransmitters na-akpali akpali dị ka dopamine, na-ahapụ ndị mmadụ n'ọnọdụ ntụrụndụ, na-ebelata ọbara mgbali, na-ebelata nkụchi obi, na ime ka obi dị jụụ.

N'ikwu ya n'ụzọ ọzọ, GABA bụ ihe na-eme ka uche na ahụ mmadụ dị jụụ.

Mgbe mmanya na-ejikọta ya na onye na-anabata GABA, ọ na-eme ka onye na-anabata GABA na-arụ ọrụ, na-eme ka ntụrụndụ dị elu, nkwụsịtụ, nkwụsịtụ, na nkwụsị nke njikwa moto.

Omume a na-eme ka ụbụrụ chee na enwere GABA na usoro karịa ka ọ dị na mbụ.

Mgbe ahụ ahụ gị na-agbalị ibelata ọdịnaya GABA iji weghachi nguzozi.

Ma n'ụtụtụ echi mgbe mmanya na-ahapụ gị, ị nwere ike nweta mmetụta nlọghachi nke nwere ike ịkpata nchekasị, nsogbu ihi ụra, na enweghị uche.

DHM na-achọpụta na mmanya na-emetụta ndị na-anabata GABA nke ụbụrụ dị ka o kwere mee, ya mere mmeghachi omume a adịghị eme ma ị gaghị enwe ike ịmaliteghachi ma ọ bụ ihe mgbaàmà n'echi ya.

DHM nwere ike mee ngwangwa ire ere nke acetaldehyde ma chebe imeju.

Dihydromyricetin na-esikwa ike ịkwado imeju iji mebie kemịkalụ acetaldehyde na-egbu egbu ozugbo enwere ike.

Mgbe ị na-aṅụ mmanya na-aba n'anya, ahụ na-akụda ya n'ime obere kemịkalụ ruo mgbe ihe niile a na-emepụta na-apụ n'anya kpamkpam.

Otú ọ dị, otu n'ime ogige ndị a na-akpọ acetaldehyde, nke na-egbu egbu ugboro 20 karịa mmanya.

Ọnụnọ nke acetaldehyde dị elu n'ime sistemu gị nwere ike ibute ụfọdụ mgbaàmà na-adịghị ahụkebe ma mụbaa mgbaàmà nhụsianya n'echi ya.

Mgbe ahụ gị jupụtara na acetaldehyde, imeju gị nwere ike wepụ ya ngwa ngwa.Agbanyeghị, DHM nwere ike inyere ahụ gị aka igbari acetaldehyde ngwa ngwa, ka ị nwee ike ịlaghachi ngwa ngwa.

Kedu mgbe m ga-ewere ya, tupu ịṅụ mmanya ma ọ bụ mgbe m nwụsịrị?

Mgbe ị na-ewere dihydromyricetin, ọ dabere na ọrụ ị na-agbalị ịrụzu.

Ya mere, dịka ọmụmaatụ, ndị nchọpụta ahụ chọpụtara na ịṅụ ọgwụ ọjọọ tupu ịṅụ mmanya na-aba n'anya belatara mmanya na-aba n'anya n'ime ọbara site na 55%.

Otú ọ dị, maka ọtụtụ ndị mmadụ, anyị na-akwado ime ya ozugbo ha ṅụsịrị mmanya, nke bụ ụzọ magburu onwe ya isi belata mgbaàmà nkwụsịtụ nke a na-enwekarị n'echi ya.

Inweta DHM mgbe ị ṅụchara mmanya na-aba n'anya nwekwara ike igbochi mmetụta nlọghachi nke GABA, na-akpọte gị mgbe niile n'etiti abalị, ma ọ bụ na-echegbu onwe gị n'echi ya.

Yabụ ị were DHM ozugbo ị ṅụchara mmanya pụtara na mmetụta ọjọọ nke mmanya ga-ebelata.

Dihydromyricetin ọ dị irè yana kedu usoro ọgwụgwọ kacha mma?

Ee.Enwere ihe akaebe zuru oke nke sayensị iji gosi na dihydromyricetin dị irè n'ibelata mmetụta nke nsị na ibelata ihe mgbu na ịkwado imeju.

Ajụjụ dị mkpa bụ, kedu ihe kacha adabara dose?

A na-eji ihe ọṅụṅụ mmanya na-aba n'anya nke 125 mg / kg mee ihe na oke oke, nke na-atụgharị na ọnụọgụ mmadụ na-eme atụmatụ nke 9-9.3 mg / lbs arọ mmadụ,

nhata na:

1,400mg maka onye 150lb

2,800mg maka onye 200lb

3,1200mg maka mmadụ 250lb

Ndị a bụ ọnụọgụ kacha nke mmadụ dabere na ọmụmụ oke.

Agbanyeghị, ekwesịrị ịtụle ihe ndị a mgbe ị na-eji usoro onunu ogwu:

Ọnụọgụ ihe ọṅụṅụ na-aba n'anya ị ririla

Ihe ọṅụṅụ na-aba n'anya dị na ihe ọṅụṅụ ahụ agwụla

Kedu ngwa ngwa ị na-aṅụ?

Ị ririla nri?

N'ezie, ọ dabere na ihe ịchọrọ iji nweta DHM n'ihi na dose achọrọ iji belata nsị dị elu karịa dose ahụ mgbe ị ṅụsịrị mmanya iji kpochapụ nkwụsị.

Ihe mgbakwunye nwere dihydromyricetin:

Ọrụ:

1) ihichapụ free radical na ahu na antioxidation: The vine tii wepụ nwere ike n'ụzọ dị irè larịị ala nke lipid peroxidation.Ọ nwere ike igbochi mmebi oxidative nke antioxidase n'ime ahụ nke radical free na-akpata.Mgbe ahụ, ọ nwere ike melite oxidation nguzogide nke ahụ mmadụ;
2) Ọgwụ nje Action: Mkpụrụ osisi vine nwere ihe mgbochi siri ike nke staphylococcus aureus na Bacillus subtilis.Ọ nwekwara mmetụta mgbochi nke Aspergillus flavus, Aspergillus niger, penicillium na Alternaria.Dihydromyricetin nwere ihe mgbochi nke Staphylococcus aureus, Staphylococcus aureus (S. aureus) na Pseudomonas aeruginosa.
3) Chebe imeju: Dihydromyricetin nwere ihe mgbochi siri ike nke ịrị elu nke ALT na AST na ọbara ọbara.Ọ nwere ike belata mkpokọta bilirubin na ọbara ọbara.Ya mere, ọ nwere mmetụta siri ike na-enye aminotransferase na jaundice.Ngwunye tii osisi vine nwere ike igbochi fibrosis imeju na oke.
4) Mbelata ọkwa shuga dị n'ọbara na abụba dị n'ọbara: Dihydromyricetin nwere ike ibelata ọkwa abụba ọbara na òké.Ọ nwere ike ibelata mmebi nke mkpụrụ ndụ imeju nke oke abụba dị n'ọbara kpatara ma melite ikike antioxidation.N'otu oge ahụ, ọ nwere ike belata ọkwa shuga dị n'ọbara.
5)Anti mbufụt: The vine tii wepụ nwere ike n'ụzọ dị irè igbochi òké pinna ọzịza kpatara xylene.Ọ nwekwara ike igbochi nzaghachi writhing na òké nke acetic acid kpatara.
6) mgbochi tumor: Na vine tii wepụ nwere irè mgbochi cell proliferation nke ụfọdụ tumor cell.

Ngwa:

Ngwaahịa ọgwụ:

A na-eji Dihydromyricetin eme ihe n'ọtụtụ ebe dị ka mgbochi mkpali, antitussive, expectorant, analgesic, ọgwụ nje antibacterial 1700ppm ma ọ bụ karịa.Maka mbadamba nkume, capsules, granules, wdg.

Ngwaahịa nlekọta ahụike:

Chebe imeju, mmetụta nkwụsịtụ.Mee ngwa ngwa ire ere nke ethanol metabolite acetaldehyde.100-800 ppm

Mbelata shuga ọbara, lipids ọbara 150-200ppm

Antioxidant, 400ppm radical free

DMY nwere ike igbochi nguzobe nke MDA na mmanụ na abụba, ma jiri ịdị ọcha kwalite ọrụ antioxidant;ọ nwere mmetụta antioxidant siri ike na mmanụ anụmanụ na mmanụ ihe oriri.

Ọtụtụ ndị na-ebubata akụrụngwa dị ka nkwenye ọkọnọ.Ụlọ ọrụ nkwado siri ike iji kwadoInstitute of botany/Institution of Microbiology/Academy of Science and Technology/University