Aha ngwaahịa:Gamma-glutamylcysteine ntụ ntụ
Okwu: gamma-L-Glutamyl-L-cysteine, γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, GGC,(2S)-2-Amino-5-{[(1R)-1-carboxy-2- sulfanylethyl] amino}-5-oxopentanoic acid, cysteine, Na-aga n'ihu-G
Ụdị mkpụrụ ndụ: C8H14N2O5S
Arọ Molecular: 250.27
Nọmba CAS: 686-58-8
Ọdịdị / agba: White crystalline ntụ ntụ
Solubility: Solubility na mmiri
Uru: precursor na glutathione
Gamma-glutamylcysteinebụ dipeptide ma bụrụ ihe na-ebute ụzọ na tripeptide ozugboglutathione (GSH).Gamma glutamylcysteine nwere ọtụtụ aha ndị ọzọ, dị ka γ -L-Glutamyl-L-cysteine , γ-glutamylcysteine ma ọ bụ GGC dị mkpirikpi.
Gamma Glutamylcysteine bụ ọcha kristal ntụ ntụ nwere usoro molekụla C8H14N2O5S na ọ nwere nha molekụla nke 250.27.Nọmba CAS maka ogige a bụ 686-58-8.
Gamma-glutamylcysteine VS Glutathione
Mkpụrụ ndụ Gamma glutamylcysteine bụ ihe na-ebute glutathione.Ọ nwere ike ịbanye n'ime sel wee gbanwee n'ime ihe antioxidant a dị ike mgbe ọ nọ n'ime ya site na enzyme njikọ nke abụọ a na-akpọ glutathione synthetase.Nke a nwere ike inye ụfọdụ ahụ efe site na nrụgide oxidative ma ọ bụrụ na ọ na-enyere sel ndị nwere nsogbu GCL aka ịgbake ma nwetaghachi ọrụ nkịtị ọzọ na ọgụ mgbe niile nke ndụ megide radicals free na-emebi anụ ahụ niile dị mma ka oge na-aga!
Ntinye uche intracellular nke gamma-glutamylcysteine (GGC) na-adịkarị ala n'ihi na ọ na-emeghachi omume na glycine iji mepụta glutathione.Usoro a na-eme ngwa ngwa, n'ihi na GGC nwere naanị ọkara ndụ nke 20 nkeji mgbe ọ nọ na cytoplasm.
Agbanyeghị, mgbakwunye ọnụ na ịgbanye glutathione enweghị ike ịbawanye glutathione cellular n'ime mmadụ.Glutathione na-ekesa enweghị ike ịbanye n'ime mkpụrụ ndụ na-emebibeghị, a ga-ebu ụzọ gbarie ya n'ime amino acid atọ, glutamate, cysteine, na glycine.Nnukwu ihe dị iche a pụtara na enwere gradient a na-apụghị imeri emeri n'etiti gburugburu extracellular na intracellular, nke na-amachibido itinye mgbakwunye cellular ọ bụla.Gamma-glutamylcysteine nwere ike ịbụ isi ihe na-ebuga GSH n'ofe ihe dị iche iche dị iche iche.
Gamma-glutamylcysteine VS NAC (N-acetylcysteine )
Gamma-Glutamylcysteine bụ ihe na-enye mkpụrụ ndụ GGC, nke ha kwesịrị imepụta Glutathione.Ihe mgbakwunye ndị ọzọ dị ka NAC ma ọ bụ glutathione enweghị ike ime nke a ma ọlị.
Gamma-glutamylcysteine usoro nke ime ihe
Kedu ka GGC si arụ ọrụ?Usoro dị mfe: ọ na-enwe ike ịbawanye ọkwa glutathione ngwa ngwa.Glutathione bụ amino acid dị mkpa nke na-arụ ọtụtụ ọrụ n'ime ahụ ma na-echebe megide nsị.Glutathione na-ekere òkè dị ka onye na-akwado otu n'ime enzymes atọ nke na-agbanwe leukotrienes iji nyere aka belata mgbaàmà ụkwara ume ọkụ, na-enyere aka n'ịtọhapụ ihe ndị na-egbu egbu na sel ka ha wee nwee ike wepụ ya site na bile n'ime stool ma ọ bụ mmamịrị, na-edozi mmebi DNA nke radicals free na ihe antioxidant ya. na-emeju glutamine mgbe mgbatị ahụ gasịrị na-eme ka ọrụ nchekwa ahụ dịkwuo mma site na mmepụta nke ọgwụ nje ndị dị ka IgA (immunoglobulin A) nke na-enyere aka chebe anyị pụọ na ọrịa iku ume n'oge oge oyi mgbe anyị kacha emetụta ya-ihe a niile mgbe ọ na-arụ ọrụ ndị dị mkpa n'ebe ndị ọzọ dị ka ịhazi metabolism!
Usoro nrụpụta Gamma-glutamylcysteine
Nmepụta ndu nke site gbaa ụka kemgbe ọtụtụ afọ ma ọ nweghị nke e mebere nke ọma.Usoro biocatalytic nke Gamma-glutamylcysteine bụ ahịa nke ọma na ụlọ ọrụ sayensị Cima.GGC dị ugbu a dị ka mgbakwunye na US n'okpuru aha ụghalaahịa nke Glyteine na Continual-G.
Uru Gamma-glutamylcysteine
Achọpụtara Gamma-glutamylcysteine na-akwalite ọkwa glutathione cell n'ime nkeji 90.Glutathione, bụ isi ihe nchebe nke anụ ahụ megide free radicals, amarawo na ọ na-enyere aka belata nrụgide oxidative site na radicals free ma kwado ọrụ dị iche iche nke anụ ahụ gụnyere detoxification.
- Na-akwado imeju, ụbụrụ, na ahụ ike na-alụso ọrịa ọgụ
- Ike antioxidant na detoxifier
Glutathione dị oké mkpa iji detoxifying ahụ gị ma na-akwado ọrụ nke imeju, akụrụ, GI tract, na eriri afọ.Glutathione na-arụ ọrụ dị mkpa n'ime ka sistemu ahụ na-arụ ọrụ nke ọma site n'inyere aka n'okporo ụzọ detoxification gụnyere ndị a na-ahụ n'ime ọbara yana akụkụ ndị bụ isi dị ka akụrụ, traktị GI, ma ọ bụ eriri afọ. - Kwalite ume, itinye uche na itinye uche
- Egwuregwu oriri na ọṅụṅụ
Ọkwa glutathione nwere ike inyere gị aka ịrụ ọrụ kachasị mma, nwee ahụike, yana gbakee ngwa ngwa.Gbaa mbọ hụ na ịbawanye glutathione site na nri ma ọ bụ mgbakwunye ka mkpụrụ ndụ ahụ wee rụọ ọrụ nke ọma ma rụọ ọrụ nke ọma ka ha wee nwee ike ibelata oge mgbake mgbe mgbatị ahụ gasịrị.
Mmetụta mmetụta Gamma-glutamylcysteine
Gamma-glutamylcysteine bụ ihe ọhụrụ na ahịa mgbakwunye, na enwebeghị mmetụta ọjọọ dị njọ akọpụtala.Ekwesịrị ị were ya dịka ndụmọdụ dọkịta gị siri dị.
Usoro ọgwụgwọ Gamma-glutamylcysteine
Ntụle nchekwa nke nnu sodium GGC n'ime oke egosila na a na-enye ọnụ (gavage) GGC adịghị egbu egbu na njedebe nke 2000 mg/kg, na-egosi enweghị mmetụta ọjọọ na-esochi usoro ọgwụgwọ ugboro ugboro kwa ụbọchị karịa ụbọchị 90.
