Ntuziaka ngwaahịa zuru oke:Kojic acid dipalmitate98% (HPLC) maka ịchacha akpụkpọ na mgbochi ịka nká
1. Okwu mmaliteKojic acid dipalmitate
Kojic acidDipalmitate (KAD, CAS79725-98-7) bụ ihe na-esi na kojic acid nweta liposoluble, nke a ma ama maka nkwụsi ike ya dị elu, ịdị mma yana nchekwa na nhazi ihe ịchọ mma. Dị ka ọgbọ na-esote tyrosinase inhibitor, ọ na-ebelata njikọ nke melanin nke ọma, na-ekwu maka hyperpigmentation, ma na-akwalite ọbụna ụda anụ ahụ. Site na ịdị ọcha nke 98% nke HPLC kwadoro, ihe a dị mma maka ngwaahịa nlekọta anụ ahụ dị elu na-elekwasị anya na ntụpọ gbara ọchịchịrị, melasma, na ngbanwe metụtara afọ.
Ngwa igodo:
- Akpụkpọ anụ: Na-egbochi mmepụta melanin site na igbochi ọrụ tyrosinase, na-eme ka acid kojic ọdịnala pụta ìhè.
- Mgbochi ịka nká: na-ebelata ahịrị dị mma ma na-eme ka akpụkpọ ahụ dịkwuo mma site na njirimara antioxidant.
- Multifunctional Formulations: dakọtara na serums, creams, sunscreens, na mgbochi ihe otutu.
2. Chemical na anụ ahụ
Ụdị mkpụrụ ndụ: C₃₈H₆₆O₆
Ibu ibu: 618.93 g/mol
Ọdịdị: White na-acha ọcha kristal ntụ ntụ
Ebe mgbaze: 92–95°C
Solubility: Mmanụ-soluble (dakọtara na esters, mmanụ ịnweta mmanụ na mmanya) .
Uru nkwụsi ike:
- pH Range: Stable na pH 4-9, dị mma maka usoro dị iche iche.
- Thermal / Light Resistance: Ọ dịghị oxidation ma ọ bụ discoloration n'okpuru okpomọkụ ma ọ bụ UV ikpughe, n'adịghị ka kojic acid.
- Metal Ion Resistance: Na-ezere chelation, na-eme ka nkwụsi ike agba ogologo oge.
3. Usoro nke Action
KAD na-arụ ọrụ site na usoro abụọ:
- Mgbochi Tyrosinase: Na-egbochi saịtị catalytic enzyme, na-egbochi njikọ nke melanin. Nnyocha na-egosi 80% dị elu karịa kojic acid.
- Mwepụta a na-achịkwa: Esterases na akpụkpọ ahụ na-eme ka KAD ghọọ kojic acid na-arụ ọrụ, na-eme ka depigmentation na-adịgide adịgide.
Uru ụlọ ọgwụ:
- Na-ebelata ntụpọ afọ, hyperpigmentation post-inflammatory (PIH), na melasma.
- Na-eme ka ọ dị mma na-ekpuchi anyanwụ site na ibelata melanogenesis nke UV kpatara.
4. Uru gafereKojic acid
| Oke | Kojic acid | Kojic acid dipalmitate |
|---|---|---|
| Nkwụsi ike | Oxidizes dị mfe, na-atụgharị edo edo | Okpomọkụ/ọkụ kwụsiri ike, enweghị ngbanwe |
| Solubility | Mmiri-soluble | Mmanụ na-agbaze, nnabata anụ ahụ ka mma |
| Ihe egwu iwe | Ọkara (pH-nwere mmetụta) | Dị ala (dị nro maka akpụkpọ ahụ nwere mmetụta) |
| Mgbanwe nhazi | Oke na pH acidic | Dakọtara na pH 4-9 |
5. Ntuziaka nhazi
Usoro ọgwụgwọ akwadoro: 1–5% (3–5% maka ịcha ọcha kpụ ọkụ n'ọnụ).
Mbanye nke nzọụkwụ site na nzọụkwụ:
- Nkwadebe nke mmanụ: gbazee KAD na isopropyl myristate/palmitate na 80 Celsius C maka nkeji 5.
- Emulsification: Gwakọta oge mmanụ na mmiri mmiri na 70 ° C, homogenize maka nkeji 10.
- Ndozi pH: Jikwaa pH 4-7 maka nkwụsi ike kacha mma.
Ụdị Ụdị (Serum na-acha ọcha):
| Ngwakọta | Pasent |
|---|---|
| Kojic acid dipalmitate | 3.0% |
| Niacinamide | 5.0% |
| Hyaluronic acid | 2.0% |
| Vitamin E | 1.0% |
| Ihe nchekwa | qs |
6. Nchekwa na nnabata
- Ndị na-abụghị Carcinogenic: Ndị na-ahụ maka nchịkwa (EU, FDA, China CFDA) kwadoro KAD maka ịchọ mma. Nnyocha e mere na-egosi na ọ dịghị ihe ize ndụ carcinogenic.
- Asambodo: ISO 9001, REACH, na Halal/Kosher nhọrọ dị.
- Eco-Friendly: E sitere na ndị na-abụghị GMO, akụrụngwa enweghị obi ọjọọ.
7. Nkwakọ ngwaahịa na ngwa ngwa
Nha dị: 1 n'arọ, 5 n'arọ, 25 n'arọ (nwere ike ịhazi ya)
Nchekwa: Ebe dị jụụ, akọrọ (<25°C), na-echebe site na ìhè.
Mbupu zuru ụwa ọnụ: DHL / FedEx maka nlele (ụbọchị 3-7), ibu ụgbọ mmiri maka nnukwu iwu (ụbọchị 7-20).
8. Gịnị kpatara ịhọrọ KAD anyị 98% (HPLC)?
- Nkwa dị ọcha: 98% kwadoro site na HPLC, na COA na MSDS nyere .
- Nkwado R&D: Ndụmọdụ teknụzụ n'efu na nnwale nlele.
- Isi mmalite na-adịgide adịgide: Mmekọrịta ya na ndị na-ebubata akwụkwọ ikike ECOCERT.
9. Ajụjụ
Ajụjụ: KAD ọ dị mma maka ụda anụ ahụ gbara ọchịchịrị?
A: Ee. Profaịlụ mgbakasị ahụ dị ala na-eme ka ọ dabara maka ụdị akpụkpọ anụ Fitzpatrick IV-VI.
Ajụjụ: KAD nwere ike dochie hydroquinone?
A: N'ezie. KAD na-enye arụmọrụ yiri ya na-enweghị cytotoxicity.
Keywords: Kojic Acid Dipalmitate, Agent Whitening Skin, Tyrosinase Inhibitor, Melanin Mbelata, Ntuzi Nhazi Nhazi, Ọgwụgwọ Hyperpigmentation, Ihe Na-acha Na-acha Stable.
Nkọwa: Chọpụta sayensị dị n'azụ Kojic Acid Dipalmitate 98% (HPLC) - anụ ahụ kwụsiri ike, anaghị ewe iwe. Mụta ndụmọdụ nhazi ya, usoro na data nchekwa maka ahịa EU/US.
