Apigenin ntụ ntụ wepụ

Iji mepụta uru ndị ọzọ maka ndị na-azụ ahịa bụ nkà ihe ọmụma azụmahịa anyị;Shopper na-eto eto bụ ịchụso ọrụ anyị maka obere MOQ maka ọnụ ahịa ọnụ ahịa China nke ihe ọkụkụApigenin ntụ ntụChebe Healthy Blood Vessels, Anyị na-anabata ịzụ ahịa, azụmahịa ụlọ ọrụ mkpakọrịta na buddies si niile ebe si gburugburu ebe obibi na-agwa anyị okwu na-achọ imekọ ihe ọnụ maka ibe uru.
Iji mepụta uru ndị ọzọ maka ndị na-azụ ahịa bụ nkà ihe ọmụma azụmahịa anyị;onye na-eto eto bụ ọrụ anyị na-achụApigenin ntụ ntụ, China Apigenin, N'ihi na ụlọ ọrụ anyị na-anọgidesi ike na njikwa echiche nke "Ịlanahụ site Quality, Development site Service, Uru site aha" .Anyị na-aghọta n'ụzọ zuru ezu na ezi kredit standing, elu àgwà ngwaahịa, ezi uche price na nkà ọrụ bụ ihe mere na ndị ahịa na-ahọrọ anyị na-ha ogologo oge azụmahịa ibe.
Apigenin, dị ka bioflavonoid a maara, egosiwo na ọ na-egosipụta ọrụ dị iche iche nke ndu, gụnyere antioxidant, mgbochi mkpali, antitumor, ant-genotoxic, anti-allergic, neuroprotective, cardioprotective, na antimicrobial. Otú ọ dị, Otu n'ime ihe ndị na-emekarị apigenin bụ isi mmalite nke apigenin. celery (Apium graveolens), ahịhịa ahịhịa na ezinụlọ Apiaceae nke a na-akọ dị ka ihe oriri kemgbe oge ochie.Apigeninbụ nri a na-amịpụta nke ukwuu na celery, nwere 108 mg apigenin kwa kg.Ọ na-arụ ọrụ dị iche iche physiological, dị ka antioxidant, ike mgbochi mkpali, antiviral omume, antibacterial na ọbara mgbali.

Aha ngwaahịa:Apigenin 98% wepụ akwụkwọ nri celery

Aha Latin: Apium graveolens L.

Nọmba CAS: 520-36-5

A na-eji akụkụ osisi: Akwụkwọ

Ngwa: Apigenin

Nyocha: Apigenin 98.0% nke HPLC

Agba: Agba aja aja ruo ntụ ntụ na-esi ísì ụtọ

Ọnọdụ GMO: GMO efu

Mbukota: na 25kgs fiber drum

Nchekwa: Debe akpa na-emegheghị n'ebe dị jụụ, ebe kpọrọ nkụ, zere ọkụ siri ike

Ndụ shelf: ọnwa 24 site na ụbọchị mmepụta

Mmetụta mgbochi tumor

Apigenin na-arụ ọrụ dị mkpa na mgbochi ọrịa kansa site n'ịkwalite apoptosis n'ahịrị sel dị iche iche.

Ọrịa Ovarian:

Achọpụtara ụfọdụ nchọpụta na apigenin nwere ike igbochi uto, mmụba, na nnyefe nke ca-ov3 (cell cancer ovarian mmadụ);ọ na-ebute apoptosis nke ca-ov3 site na idobe mkpụrụ ndụ kansa kansa na oge G2/M.Mmetụta metụtara oge na dose.

Ọrịa cancer pancreatic:

Apigenin nwere ike igbochi mmụba nke mkpụrụ ndụ kansa pancreatic.Apigenin na-agụ etuto ahụ agụụ site n'ibelata isi iyi nke glucose, nke bụ nri nke mkpụrụ ndụ ọrịa cancer bi na ya.E wezụga nke ahụ, Apigenin nwere ike imeziwanye irè ọgwụ chemotherapy-gemcitabine.

Chemo-uche

Achọpụtara na apigenin na ọdịnaya dị ala nwere mmetụta cytotoxic dị ala na enweghị ike ime ka mkpụrụ ndụ myeloid leukemia buru ibu (hl-60) banye apoptosis nke ọma.Otú ọ dị, apigenin nwere ike ịkwalite mmetụta mgbochi nke cisplatin (DDP) na mmụba cell hl-60 mgbe ọ na-ejikọta ya na nchịkọta dị iche iche nke DDP.Ya mere, Apigenin nwere ike inwe mmetụta mmetụta chemotherapy na hl-60;Ọnụ ala dị ala nke apigenin nwekwara ike ibelata nguzogide nke mkpụrụ ndụ hl-60 na apoptosis na-ebute chemotherapy, nke nwere ike jikọta na nhazi ala nke NF-κB na BCL-2.(NF-KB bụ ụdị mgbagwoju anya protein nke na-achịkwa ederede DNA, mmepụta nke cytokines na ndụ cell; BCL-2 bụ nke etinyere n'ime ahụ site na mkpụrụ ndụ BCL2, ọ bụ onye mbụ nke ezinụlọ BCL-2 na-achịkwa ndị na-edozi ahụ. nwere ike ịchịkwa ọnwụ cell)

Nchekwa imeju

Apigenin nwere ike ibelata mmerụ ahụ imeju nke ischemia-reperfusion na-ebute site na lipid peroxidation na-emegide ma na-ekpochapụ radicals efu.

Apigenin nwere ike ibelata mmerụ ahụ imeju na-akpata site na nrụgide oxidative n'ihi ike antioxidant na ọrụ mgbochi mkpali.

Nnwale ọgwụ ọgwụ egosila na apigenin nwere mmetụta nchebe pụtara ìhè na mmerụ ahụ na-egbu mmanya na-akpata imeju / hepatocyte, na usoro ya bụ isi metụtara mgbochi nke okwu CYP2E1 na imeju / hepatocyte.

Gbochie ọkpụkpụ ọkpụkpụ

Apigenin na-egbochi osteoblastogenesis, osteoclastogenesis, ma na-egbochikwa ọkpụkpụ ọkpụkpụ.

Apigenin na-echebe anụ ahụ ọkpụkpụ site na ibelata ọkpụkpụ ọkpụkpụ n'ime ahụ.

Ụfọdụ ọmụmụ metụtara MC3T3-E1, osteoblast precursor cell line nke sitere na Mus musculus (mouse) calvaria, chọpụtara na apigenin nwere ike igbochi TNF-α, IFN-γ, wee mee ka nzuzo nke ọtụtụ cytokines na-akwalite nhazi osteoclast.

Apigenin na-egbochikwa ọdịiche nke 3T3-L1 adipose precursor cell n'ime adipocytes ike, ya mere na-egbochi ndị na-eje ozi dị iche iche na-egbochi adipocyte iche iche-induced IL-6, MCP-1, lectin ngwaahịa.

Apigenin na-egbochi ọdịiche nke osteoclasts site na ahịrị cell RAW264.7 wee gbochie nhazi nke osteoclasts multinucleated.Ọ nwekwara ike ịkpata apoptosis osteoclast ma gbochie ntugharị ọkpụkpụ.

Ọrụ mgbochi mkpali na mgbochi oxidant

Apigenin na-egbochi usoro mbufụt, na-abawanye ọkwa IL-10 ma na-emezi usoro nrụgide oxidative.

Apigenin na-egbochi cytokines pro-inflammatory ma na-ebute mmepụta cytokine mgbochi mkpali.

Ụfọdụ akwụkwọ na-egosi na apigenin na-ebelata mbufụt anụ ahụ nke nrụgide oxidative na-akpata site n'ịgbanwe ihe nrịbama nrụgide oxidative, interleukins, ihe nrịbama enzyme ọbara, na nkwupụta nke ọtụtụ enzymes ndị ọzọ metụtara ya.

Usoro nke usoro endocrine

Achọpụtara na apigenin nwere ike ịbawanye ọkwa insulin na thyroxine na anụmanụ ndị na-arịa ọrịa shuga, na-ebelata mkpokọta shuga ọbara na ọrụ nke glucose-6-phosphorylase (G. 6-Pase).

Apigenin tụgharịrị mmetụta nke cholesterol ọbara na-abawanye, ịba ụba lipid peroxidation (LPO) na mbelata ọrụ nke antioxidants dị ka catalase (CAT) na superoxide dismutase (SOD) n'ime anụmanụ ndị na-akpata alloxan.

N'ime ụmụ anụmanụ nwere shuga ọbara mgbe niile, apigenin nwekwara ike ibelata serum cholesterol na imeju peroxidation lipid, ma mụbaa ọrụ antioxidants na sel.

Njirimara ọgwụ nke apigenin

Apigenin etinyela nnukwu mkpa n'afọ ndị na-adịbeghị anya, dị ka onye na-akwalite ahụike bara uru n'ihi nsi ya dị ala na mmetụta ahụike ya na mkpụrụ ndụ kansa mgbe niile, ma e jiri ya tụnyere flavonoids ndị ọzọ nwere njikọ.Enwere otutu ihe akaebe na-egosi na apigenin nwere ikike ọgwụgwọ dị ukwuu maka ọtụtụ ọrịa

Ọrụ:

-Igbochi uto mkpụrụ ndụ kansa.

-Ibelata ọbara mgbali

-Na-echebe sistemu obi obi

-enyere aka ihi ụra, akwara dị jụụ, wepụ iwe iwe

-guzogide mbufụt

-gbochi osteoporosis

- mmetụta diuretic.

- Na-egbochi nchịkọta platelet.

Ngwa:

-Agba ọgwụ, ngalaba nlekọta ahụike