PRL-8-53, nootropic Kacha ọhụrụ, nke a makwaara site na aha kemịkal ya Methyl 3-[2-[benzyl(methyl)amino]ethyl] benzoate bụ ihe mgbakwunye nootropic sịntetịt.Ọ bụ Dr. Nikolaus Hansl mepụtara ya na 1970 na Mahadum Creighton na Nebraska.O nweela ụfọdụ ọmụmụ mmadụ nke gosipụtara nzaghachi dị mma na ọrụ ọgụgụ isi.Otu nnyocha gosiri na ogige ahụ nwere ike inye aka weghachite ncheta furu efu (hypermnesia).
Aha ngwaahịa: PRL-8-53
Aha ndị ọzọ: Methyl 3- (2- (benzylmethylamino) ethyl) benzoate hydrochloride
3- (2-benzylmethylaminoethyl) benzoic acid methyl ester hydrochloride
3- (2- (Methyl (phenylmethyl) amino) ethyl) benzoic acid methyl ester hydrochloride.
Nọmba CAS: 51352-87-5
Nyocha: 98%
Ọdịdị: White ntụ ntụ
Kedu ka PRL-8-53 si arụ ọrụ?
PRL-8-53 sitere na nchikota benzoic acid na phenylmethylamine.Usoro kemịkalụ nke a na-emepụta site na nchikota nke ogige abụọ a na-eme ka ngwakọta nke nwere ike imekọrịta ihe na ndị na-anabata cholinergic, nke na-etinye aka n'ịgbanwe ebe nchekwa na usoro mmụta n'ime ụbụrụ.PRL-8-53 makwaara na ọ nwere ike (na-abawanye mmetụta nke) dopamine na akụkụ ụfọdụ na-egbochi ndị na-anabata serotonin.Dr. Nikolaus Hansl kwenyere na profaịlụ mmetụta a nwere ike iduga ngbanwe nke nguzozi na sistemụ neurotransmitter CNS ma mee ka ọrụ ọgụgụ isi dịkwuo mma.
Enwere naanị otu ọmụmụ ụlọ ọgwụ nke mmadụ na-ebute ụzọ iji nyochaa mmetụta nke ọgwụ ahụ ma gosipụta ọganihu na ebe nchekwa okwu, oge mmeghachi omume na-ahụ anya na njikwa moto, karịsịa na ndị nọ n'afọ 30. Ndị agadi na-emekarị ka ha bụrụ ndị ọzọ n'okpuru ebe nchekwa. na mbelata nke ọgụgụ isi, ya mere, ebe nchekwa na ihe mgbakwunye na-eme ka ọgụgụ isi na-arụ ọrụ nke ọma na ha.
Ọrụ RPL-8-53:
Kwalite ọgụgụ isi
Mee ka ebe nchekwa dị elu na ike ịdabere
Melite ike ụbụrụ iji dozie nsogbu ma chebe ya pụọ na mmerụ ahụ kemịkal ma ọ bụ anụ ahụ ọ bụla
Kwalite ọkwa mkpali
Kwalite njikwa nke usoro ụbụrụ cortical/subcortical
Melite nghọta nghọta
Usoro onunu ogwu na mmetụta
Ozi patent dị maka PRL 8-53 na-atụ aro oke nke 0.01-4mg/kg nke arọ ahụ.Otú ọ dị, dị ka nke ahụ bụ nnukwu oke, oke dị mma bụ 0.05-1.2 mg / kg.Nke a na-atụgharị na 3.4mg-81.6mg maka onye 150 pound na 4.55mg-109mg maka onye 200 pound.N'ime ule mmadụ, ọ nweghị mmetụta ọ bụla e dekọrọ;Otú ọ dị, a chọpụtara obere ọrụ moto na ụmụ oke na oke mgbe enyere ya nnukwu doses nke PRL 8-53.
