Aha ngwaahịa: S-adenosyl-L-methionine disulfate tosylate
Aha ndị ọzọ: Ademetionine disulfate tosylate; AdeMethionine disulfate Tosylate; SAM-TAdemetionine disulfate tosylate; Ademetionine disulfate TosylateOtu)
CAS Mba:97540-22-2
Nyocha: 98% nkeji
Agba: White ezi ntụ ntụ
Ọnọdụ GMO: GMO efu
Mbukota: na 25kgs fiber drum
Nchekwa: Debe akpa na-emegheghị n'ebe dị jụụ, ebe kpọrọ nkụ, zere ọkụ siri ike
Ndụ shelf: ọnwa 24 site na ụbọchị mmepụta
SAME na-enye otu methyl onyinye n'ụdị biosynthesis nke protein, neurotransmitters, nucleic na nucleic acid. Nke a na-eme n'ọtụtụ mmeghachi omume transmethylation enzymatic.
Adenosylmethionine (SAME) bụ ihe na-eme n'ọdịdị nke a na-ahụ n'ihe fọrọ nke nta ka ọ bụrụ anụ ahụ na mmiri ọ bụla dị n'ime ahụ. Ọ na-etinye aka na ọtụtụ usoro dị mkpa. SAME na-ekere òkè n'ime usoro ahụ ji alụso ọrịa ọgụ, na-edobe membranes cell, ma na-enyere aka ịmepụta na imebi kemịkalụ ụbụrụ, dị ka serotonin, melatonin, na dopamine.
Iwere SAME n'ọnụ yiri ka ọ na-arụ ọrụ yana ibuprofen na ọgwụ ndị ọzọ yiri ya maka ibelata mgbaàmà nke osteoarthritis. Mana ọtụtụ mmadụ kwesịrị ịnara SAME ihe dịka otu ọnwa tupu ahụ adị ha mma.
Ndị mmadụ na-ejikarị SAME agwọ ịda mbà n'obi, osteoarthritis na ọrịa imeju. Agbanyeghị, SAME nwekwara ike iji ọgwụ antidepressant na-emekọrịta ihe.
Ọ nwere ike mebie ihe ndị na-emerụ ahụ n'ime ahụ. Ndị a gụnyere ọla ndị dị arọ. Ọ nwekwara ike igbochi mmebi imeju site na nsị acetaminophen ma nyere aka gbochie ntinye abụba n'ime imeju gị. Ọ nwekwara ike inye aka belata ike ọgwụgwụ ma belata ihe ize ndụ nke ịkwọ isi n'oge.
Na mkpụrụ ndụ eukaryotic, SAM na-eje ozi dị ka onye na-achịkwa usoro dị iche iche gụnyere DNA, tRNA, na rRNA methylation; nzaghachi mgbochi; amino acid metabolism; transsulfur; na ndị ọzọ. N'ime osisi, SAM dị mkpa maka biosynthesis nke ethylene, hormone dị mkpa na ihe ọkụkụ na-egosi.
T-Adenosylmethionine (SAMe) bụ ihe na-eme n'ọdịdị nke a na-ahụ n'ihe fọrọ nke nta ka ọ bụrụ anụ ahụ na mmiri ọ bụla n'ime ahụ. Ọ na-etinye aka na ọtụtụ usoro dị mkpa. SAME na-ekere òkè n'ime usoro ahụ ji alụso ọrịa ọgụ, na-edobe membranes cell, ma na-enyere aka ịmepụta na imebi kemịkalụ ụbụrụ, dị ka serotonin, melatonin, na dopamine.
Ọrụ
Transmethylation
SAME bụ onye na-enye onyinye methyl kacha mkpa n'ime ahụ, ma ọ dịkarịa ala 35 dị iche iche methyl transferase mmeghachi omume ka achọtara SA M dị ka onye na-enye onyinye methyl. A na-eji SAM eme ihe maka biosynthesis nke ọtụtụ ihe nitrogen, dị ka creatine, choline, epinephrine, pinecone, carnitine, na myosin.
Transaminopropyl ọrụ
SAME na-ekere òkè na njikọ nke bioamines site na transaminopropyl. Spermidine na spermidine bụ polyamines dị mkpa na eukaryotes. Mgbe nkesa abụọ gasịrị, SAM na-emepụta 5 '-methiodophyl (MTA), wee nyefee aminopropyl na puttriamine ma ọ bụ spermidine iji mepụta spermidine na spermidine kwekọrọ.
Trans sọlfọ ọrụ
SAME bụ ihe mmalite na-arụ ọrụ nke ogige ndị nwere sọlfọ dị ka cysteine na glutathione (GSH). SAM na-emepụta homocysteine site na ngbanwe nke sọlfọ, na-esote ọgbọ catabolic nke cysteine, nke na-emezigharị n'ime glutathione (GS H).
Ngwa
Ọgwụgwọ ịba ọcha n'anya
Dị ka adenosylmethionine exogenous, S-adenosylmethionine nwere ike ịgbakwunye adenosylmethionine endogenous na ụmụaka nwere mmebi imeju, belata mgbasa nke cholic acid nke ọma, na-echebe mkpụrụ ndụ imeju mebiri emebi, ma kwalite nlọghachi nke jaundice. Na mgbakwunye, S-adenosine methionine na-arụkwa ọrụ nke ọma n'ịgwọ ọrịa imeju ụmụaka.
Ọgwụgwọ ọrịa imeju na-egbu egbu
A chọpụtala na s-adenosine na ọgwụgwọ nke ndị ọrịa nwere ịba ọcha n'anya na-egbu egbu nwere ike imeziwanye agụụ ha dara ogbenye, ọgbụgbọ, ọgbụgbọ, ike ọgwụgwụ, mgbakasị afọ, itching akpụkpọ ahụ na mgbaàmà ndị ọzọ, n'otu oge ahụ na-ebelata ọbara bilirubin ma melite ọrụ imeju. nwere mmetụta dị mma, yana iji nchekwa mee ihe, ọ dịghị mmeghachi omume ọjọọ doro anya a chọtara na usoro ọgwụgwọ. Mana ọgwụgwọ ịba ọcha n'anya na-egbu egbu, ịghara ịṅụ mmanya na-aba n'anya dị oke mkpa, bụkwa usoro ọgwụgwọ ya kachasị mkpa.
Ọgwụgwọ cholestasis intrahepatic nke afọ ime
S-adenosyl-L-methionine ntụ ntụ nwere ike imeziwanye ihe ngosi biochemical nke cholestasis na mgbaàmà prurituria, ya mere a na-ewere na S-adenosine bụ otu n'ime ọgwụ dị mma ma dị irè maka ọgwụgwọ nke cholestasis intrahepatic.
