10-Deacetylbaccatin III (10-DAB)

10-Deacetylbaccatin III (10-DAB) Chithunzi Chowonetsedwa
  • 10-Deacetylbaccatin III (10-DAB)

Kufotokozera Kwachidule:

10-Deacetylbaccatin III (C29H36O10) ndi bioactive diterpenoid yotengedwa kuchokera ku singano ndi khungwa la singano.Misonkhomitundu (yew mitengo). Monga kalambulabwalo wofunikira mu semi-synthesis ya paclitaxel, docetaxel, ndi ma taxane-based chemotherapeutic agents, 10-DAB imagwiritsidwa ntchito kwambiri pakupanga mankhwala a R&D komanso kupanga mankhwala a oncology.

10-Deacetylbaccatin III, yomwe imadziwikanso kuti 10-DAB kapena 10-DAB III, imakhala yogwirizana kwambiri ndi mankhwala achilengedwe omwe amachokera ku singano zouma ndi nthambi zazing'ono za mtengo wa yew wa ku Ulaya (Taxus baccata) . pacitaxel (taxol); cabazitaxel. 10-10-deacetylbaccatin III inapezeka kuti imalepheretsa kukula kwa L. DONOVANI intracellular amastigotes mkati mwa J774 murine macrophages in vitro pa nanomolar concentrations ndi IC (50) mtengo wa 70 nM.


  • Mtengo wa FOB:US 5 - 2000 / KG
  • Kuchuluka kwa Min.Order:1 kg
  • Kupereka Mphamvu:10000 KG / Mwezi
  • Doko:Shanghai / Beijing
  • Malipiro:L/C,D/A,D/P,T/T,O/A
  • Migwirizano Yotumizira:Panyanja/Ndi Air/By Courier
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    Zogulitsa Tags

    Dzina la Chemical: 10-Deacetylbaccatin III

    Nambala ya CAS:

    32981-86-5
    Mawu ofanana ndi mawu:

    10-Desacetylbaccatin III; 10β-Deacetylbaccatin III; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-imodzi; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-imodzi, 12b-(acetyloxy) -12-(benzoyloxy) -1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-; (Docetaxel USP Chidetso);10-Deacetylbaccatin III; 10-Deacetyl baccatin; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS) -1,2a,3,4,4a,6,9,10,11,12,12a, 12b-Dodecahydro-4,6,9,11,12,12b-hexahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-imodzi 12b-acetate, 12-acetate (USP-benzo);
    Mawonekedwe a Molecular: C29H36O10
    Maonekedwe: Zoyera Zolimba
    Mol. Kulemera kwake: 544.6
    Posungira: 2-8 ° C Firiji

    Subtitle: Plant-Derived API Intermediate, CAS32981-86-5| | GMP Certified, COA Yoperekedwa

    10-Deacetylbaccatin III ndi chiyani?10-DAB)?

    10-Deacetylbaccatin III (C29H36O10) ndi bioactive diterpenoid yotengedwa kuchokera ku singano ndi khungwa la singano.Misonkhomitundu (yew mitengo). Monga kalambulabwalo wofunikira mu semi-synthesis ya paclitaxel, docetaxel, ndi ma taxane-based chemotherapeutic agents, 10-DAB imagwiritsidwa ntchito kwambiri pakupanga mankhwala a R&D komanso kupanga mankhwala a oncology.

    Zofunikira Zazikulu & Mawonekedwe

    • Kuyera: ≥98% (HPLC-UV yovomerezeka, COA ilipo)
    • Maonekedwe: ufa woyera mpaka woyera
    • Kusungunuka: Kusungunuka mu methanol, ethanol, DMSO; sungunuka pang'ono m'madzi
    • Kusungirako: Kukhazikika pa -20 ° C m'zotengera zopanda mpweya, zotetezedwa ku kuwala
    • Zomera: Zokolola zokhazikikaTaxus wallichiana(Himalayan uwu)

    Mapulogalamu a 10-DAB

    1. Anticancer Drug Synthesis
      • Zofunikira zapakatikati pakupanga semi-synthetic ya paclitaxel (Taxol®) ndi docetaxel (Taxotere®).
      • Imagwiritsidwa ntchito mu R&D pazotulutsa zatsopano za taxane zolunjika ku khansa yosamva mankhwala.
    2. Kafukufuku wa Biochemical
      • Kuphunzira kwa njira za tubulin polymerization ndi kulowetsedwa kwa apoptosis.
      • Reference standard for analytical chemistry and control control.
    3. Natural Product m'zigawo
      • High-zokolola m'zigawo ndondomeko ogwirizana ndi mfundo zobiriwira umagwirira.

    Chifukwa Chake 10-DAB Kuchokera kwa Ife?

    ✅ Ubwino Wotsimikizika:

    • Satifiketi Yowunikira Gulu (COA) yokhala ndi data ya HPLC, MS, NMR.
    • Imagwirizana ndi malangizo a USP, EP, ndi ICH Q7 GMP.

    ✅ Sustainable Sourcing:

    • Zokololedwa bwino m'minda ya Taxus yolimidwa (CITES Appendix II ikugwirizana).

    ✅ Global Logistics:

    • Kutumiza mosasunthika kozizira kumadera aku USA, EU, ndi APAC.
    • Kuyika makonda (1g mpaka 1kg, mbale zagalasi za amber zokhala ndi desiccant).

    Thandizo Laukadaulo & Zolemba

    • MSDS yaulere (Material Safety Data Sheet) ndi kukhazikika kwa data mukafunsidwa.
    • Kaphatikizidwe mwamakonda ndi mitengo yambiri yopezeka kwa ogwirizana ndi OEM.
    • Thandizo lodzipatulira pakuwongolera zoperekedwa ndi IND/NDA.

    Chitetezo & Kutsata

    • Nambala ya CAS: 32981-86-5
    • Ma Code Hazard: Gwirani ndi PPE (magolovesi, magalasi) - osawopsa kwa akatswiri.
    • Mkhalidwe Wowongolera: REACH adalembetsa; DMF ikupezeka kwamakasitomala azamankhwala.

    Ma FAQ a 10-DAB

    Q: Kodi 10-DAB ingagwiritsidwe ntchito mwachindunji mu maphunziro a chikhalidwe cha ma cell?
    A: Ayi. Pamafunika kusintha kwa mankhwala (mwachitsanzo, kuwonjezera unyolo) kuti akhale misonkho ya bioactive.

    Q: Kodi nthawi yotsogolera 500g ndi iti?
    A: Nthawi yopangira: masabata a 2-3. Kutumiza kwa Express kulipo.

    Q: Kodi mumapereka ma protocol a taxane synthesis?
    A: Inde! Mapepala oyera aukadaulo opezeka kwamakasitomala oyenerera.

    Kufotokozera:
    Gwero 98% HPLC-grade 10-Deacetylbaccatin III (CAS 32981-86-5) - GMP-certified Taxus extract for paclitaxel synthesis. Maoda ambiri, COA/MSDS, ndi chithandizo chowongolera chikuphatikizidwa.

    1. Mawu osakira:
      • Choyambirira: "10-Deacetylbaccatin III wogulitsa", "High purity 10-DAB", "Paclitaxel precursor"
      • Mchira wautali: "CAS 32981-86-5 mtengo", "Taxus extract for cancer research", "GMP 10-DAB"
    2. Mawu osakira:
      • "Taxane intermediate", "semi-synthetic paclitaxel", "C29H36O10", "yew tree compound"
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