E tusa ai ma Wikipedia, o le igoa IUPAC o le piperlongumine o le 1- [(2E) -3- (3,4,5-Trimethoxyphenyl) prop-2-enoyl] -5,6-dihydropyridin-2 (1H) -one, ma nisi 'upega tafaʻilagi e sili ona faʻaaoga le 5,6-dihydro-1-[(2E) -1-oxo-3-(3,4,5-trimethoxyphenyl) -2-propenyl] -2 (1H) -pyridinone.
Ole igoa ole vailaʻau atoa ole piperlongumine e umi ma e le mafai e tagata ona manatua, o lea e faʻaaoga ai e le au suʻesuʻe le piplartine poʻo le piperlongumine i le tele o pepa faʻasaienisi.Ma o le 20069-09-4 o lona numera resitalaina CAS.
Igoa o oloa:Piperlongumine pauta
Isi Igoa: Piplartin,Piperlonguminefua, Piplartine, 5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone,PPLGM , pippali pauta, Piper Longum extract
CAS Nnumera:20069-09-4
Punavai Fa'asao:Piper Longum Linn
Su'ega: 98% min
Fa'ata'ita'iga fua: Avanoa
Fa'aaliga: Pa'epa'e tioata pa'epa'e
Faamanuiaga: Anti-kanesa, anti-matua, senolytic
Soifua Fa'asao: 2 tausaga
Piperlonguminee tele lava ina maua i Piper longum, o se laau e afua mai i Asia i Saute.Initia ma Saina o atunuu autu ia e lua o loʻo faʻatau atu pisinisi Piper longum powders ma faʻaopoopoga i luga ole Amazon ma isi upega tafaʻilagi e-commerce.
Piper longum e masani ona lauiloa o le pepa umi poʻo le pippali i Initia.Piper longum o loʻo i ai alkaloids, amides, Lignans, Esters, suauu faʻafefe, ma isi.
O le Piper longum fruit ua faʻaaogaina i le Ayurvedic system of medicine and Traditional Chinese Medicines mo se taimi umi lava.
Piperlongumine Fa'amatalaga
E leai se pauta tele o le pipelongumine i luga o le maketi i le taimi nei.O le tele o fa'atau oloa o kamupani fa'afofoga, ma o latou oloa e mo na'o su'esu'ega fa'aoga.E le gata i lea, o latou aofaʻi e masani lava naʻo le 10mg i le 500mg i totonu o se fagu laʻititi.
O loʻo i ai fua faʻatatau o laʻau piper longum, faʻatasi ai ma faʻamatalaga lauiloa e pei ole 4: 1, 10: 1, 20: 1, ma isi.
O fuala'au a Initia o lo'o i ai le piperlongumine e masani lava ona maua fua fa'atatau.E fia piperlongumines o iai?E leai se tasi na te iloa.E na'o le piperlongumine fa'asalalau mai le piper longumine e mafai ona fuaina.
faʻamatalaga e 98% min.
Afai ei ai sau fesili, faamolemole aua le faatuai e faafesootai matou mo nisi faamatalaga.
Piperlongumine solubility
Piperlongumine e le solu i le vai.O lea, afai e te manaʻo e faʻaoga atoatoa le piperlongumine supplements, e tatau ona e faia le piperlongumine i foliga o capsules nai lo piperlongumine tablets poʻo paʻu.
O le Piperlongumine e mafai ona solu i solu faʻaletino e pei ole ethanol, DMSO, ma le dimethylformamide (DMF).
Mechanism of Action of Piperlongumine
Fa'amanuiaga ole Piperlongumine
I le avea ai o se vailaʻau faʻaleaganuʻu faʻaaogaina i Saina ma Initia, o le piper longum laau ua lipotia mai o se manava manava, ma e lelei mo le faʻaogaina lelei o le gaogao ma le puipuiga.
Mo le piperlongumine lava ia, anti-kanesa ma anti-matua o popolega autu ia e lua.
Piperlongumine mo le anti-matua (senolytic)
Piperlongumine o se sui senolytic fou.Afai e te fia iloa pe faʻafefea ona aoga le piperlongumine mo le anti-matua, e tatau ona e iloa muamua sela matua.
E taua tele le sao o sela fa'apitoa i le tele o fa'ama'i e fa'atatau i le matua.E mafai ona tatou faapea atu o sela matutua o le pogai lea o le matua.
E faapefea la ona foia ia faamai?O le auala pito sili ona faigofie o le tapeina o nei sela matutua!O sela fa'amasani o ga'o ga'o ga'o ga'o e fa'aputu i le matua i a'au ma totoga uma o lou tino.Piperlongumine fa'aoso apoptosis i sela matutua ma fasiotia i latou e ala i se ROS-tutoatasi masini.
E mafai e le Piperlongumine ona fa'agesegese le fa'atupuina o sela matutua, filifili fa'atama'ia sela matutua ma fa'aola lou soifua maloloina.E aoga lelei ma isi mea e faʻamaʻi ai le matua, e pei o le pterostilbene, resveratrol, fisetin, ma isi.
Piperlongumine fa'ata'ita'iga falema'i
Piperlongumine ua suʻesuʻeina tele i togafitiga o le kanesa o loʻo alu aʻe i faʻataʻitaʻiga falemaʻi.Talu mai le lipoti muamua e fesoʻotaʻi ma lona faʻaogaina i suʻesuʻega o le kanesa (i le 2011) e tusa ma le 80 pepa na faʻasalalau i lalo ifo o le 10 tausaga, ae o loʻo tumau pea se va.E leai ni suʻesuʻega metabolism o le piperlongumine i le tino o le tagata.
Piperlongumine a'afiaga
E leai ni a'afiaga leaga ua lipotia mai.
