LL-DOPA imhando yechisikigo yeDOPA inoshandiswa mukurapa chirwere cheParkinson.L-DOPA ndiyo inotangira dopamine uye chigadzirwa che tyrosine hydroxylase.Target: Dopamine Receptor L-DOPA (L-3,4-dihydroxyphenylalanine) ikemikari inogadzirwa uye inoshandiswa sechikamu chezvakajairwa biology yevanhu, dzimwe mhuka nemiti.Dzimwe mhuka nevanhu vanozviita kuburikidza ne biosynthesis kubva kune amino acid L-tyrosine.L-DOPA ndiyo inotungamira kune neurotransmitters dopamine, norepinephrine (noradrenaline), uye epinephrine pamwe chete inozivikanwa secatecholamines.L-DOPA inogona kugadzirwa uye muchimiro chayo yakachena inotengeswa seapsychoactive drug neINN levodopa;mazita ekutengeserana anosanganisira Sinemet, Parcopa, Atamet, Stalevo, Madopar, Prolopa, etc. Semishonga inoshandiswa mukurapa kwechirwere cheParkinson uye dopamine-responsive dystonia.L-DOPA inoyambuka inodzivirira yeropa-brain barriers, nepo dopamine pachayo haigone.Nokudaro, L-DOPA inoshandiswa kuwedzera dopamine concentrations mukurapa kwechirwere cheParkinson uye dopamine-responsive dystonia.Kurapa uku kwakaitwa kunoshanda uye kunoratidzwa kiriniki naGeorge Cotzias nevamwe vaaishanda navo, kwavakahwina mubairo we1969 Lasker.Pamusoro pezvo, L-DOPA, inotungamirwa pamwe chete neiyo peripheral DDCI, yakaongororwa semushonga ungangoita wekusagadzikana gumbo syndrome.Nekudaro, zvidzidzo zvakaratidza "hapana mufananidzo wakajeka wezviratidzo zvakaderedzwa".L-DOPA ndiyo inotungamira kune neurotransmitters dopamine, norepinephrine (noradrenaline), uye epinephrine (adrenaline) pamwe chete inozivikanwa secatecholamines.
Kunze kwechisikigo uye chakakosha basa rekubereka, L-DOPA inoshandiswawo mukurapa kwekiriniki yechirwere cheParkinson uye dopamine-responsive dystonia.Kana ichishandiswa mune yemishonga, iyo INN zita rekuti 'levodopa' rinowanzo shandiswa.
Levodopa inongoitika yechikafu yekuwedzera uye psychoactive mushonga unowanikwa mune mamwe marudzi echikafu nemakwenzi (semuenzaniso, Mucuna pruriens, kana velvet bhinzi), uye inogadzirwa kubva kuamino acid L-tyrosine mumuviri wemammalian uye uropi.
Levodopa ndiyo inotungamira kune neurotransmitters dopamine, norepinephrine (noradrenaline), uye epinephrine (adrenaline) pamwe chete inozivikanwa secatecholamines.
Kunze kwechisikigo uye chakakosha basa rekubereka, L-DOPA inoshandiswawo mukurapa kwekiriniki yechirwere cheParkinson uye dopamine-responsive dystonia.Kana ichishandiswa mune yemishonga, iyo INN zita rekuti 'levodopa' rinowanzo shandiswa.
Product Name: L-dopa 98%
Botanical Source: Mucuna Pruriens Extract
Chikamu: Mbeu (Yakaomeswa, 100% Yakasikwa)
Active Ingredient: Levodopa (L-dopa)
Kuchera Nzira: Mvura / Zviyo Doro
Fomu: kure-white powder
Mutengo: 5% -99%
Test Method: HPLC
Nhamba yeCAS: 59-92-7
Molecular formal: C9H11NO4
Molecular uremu: 197.19
Solubility: Yakanaka solubility muhydro-doro mhinduro
GMO Mamiriro:GMO Yemahara
Kurongedza: mune 25kgs fiber zvigubhu
Kuchengeta: Chengetedza mudziyo usina kuvhurwa munzvimbo inotonhorera, yakaoma, Chengetedza kure nechiedza chakasimba
Sherufu Hupenyu: Mwedzi makumi maviri nemana kubva pazuva rekugadzirwa
Basa:
- 1 .Inorwisa-paralysis agitans.Kuburikidza neropa-brain chipingamupinyi muhuropi tishu, asi neiyo decarboxylation yedopa decarboxylase mu dopamine, ita basa.
2. Nokuda kwekudedera kwakakosha uye kuoma mitezo agitans syndrome yevasina-drug immunogenicity, uye mune chiedza chiri nani, chakanyanya, kana vakwegura varombo.
3. Kurudzira kukura kwemhasuru, kuderedza uremu.
4. Kuwedzera kwepfupa uye kuchinjwa kwe osteoporosis.
5 .Dietary supplements.
6. Kurapa parkinsonism uye Pakinsonism syndrome, hepatic coma, hub mabasa kuvandudza murwere kumuka, zviratidzo kuvandudzwa.
7 .Kurudzira kurara, vandudza immune system.
8 .Kuderedza uremu.
9 .Kuwedzera kusimba kwemapfupa uye kutendeuka kweosteoporosis, wedzera simba remhasuru, wedzera libido uye kuita zvepabonde.
Application:
1.Mucuna Pruriens Extract inogona kushandiswa sezvokudya zvinowedzera.
2.Mucuna Pruriens Extract inoshandiswa sechikamu muzvinyorwa zvegungwa zvinoshandiswa nehupenyu hwepelagic.
3.Mucuna Pruriens Extract inogona kukurudzira kukura kwemisumbu uye kuwedzera kwepfupa uye kuchinjwa kwe osteoporosis.
4.Mucuna Pruriens Extract inowedzera kuwedzera kwepfupa uye kuchinjwa kweosteoporosis, kuwedzera simba remhasuru, kuwedzera libido uye kuita zvepabonde.
5.Mukushandiswa kwekliniki, Mucuna Pruriens Extract inoshandiswa mukutarisira chirwere cheParkinson uye dopa-responsive dystonia.
6.Kudengenyeka kwakakosha uye kuoma mitezo agitans syndrome yevasina-drug immunogenicity, uye mune chiedza chiri nani, chakanyanya, kana vakwegura varombo.
7.Treat parkinsonism uye Pakinsonism syndrome, hepatic coma, hub mabasa ekuvandudza murwere akamuka, zviratidzo zvekuvandudza.
8.Mucuna Pruriens Extract is anti-paralysis agitans.Kuburikidza neropa-brain chipingamupinyi muhuropi tishu, asi neiyo decarboxylation ye-l-dopa decarboxylase mu dopamine, ita basa.
9.Mucuna Pruriens Extract inoshandiswa pakudengenyeka kwakakosha uye kuora mitezo agitans syndrome yevasina-drug immunogenicity, uye mune chiedza chiri nani, chakanyanya, kana vakwegura varombo.
Mamwe ruzivo nezve TRB | ||
Regulation certification | ||
USFDA,CEP,KOSHER HALAL GMP ISO Zvitupa | ||
Kuvimbika Hunhu | ||
Anoda kusvika makore makumi maviri, kunze kwenyika makumi mana nematunhu, mabheji anopfuura zviuru mazana maviri anogadzirwa neTRB haana chero matambudziko emhando, nzira yekucheneswa, kusachena uye kuchena kutonga zvinosangana neUSP, EP uye CP. | ||
Comprehensive Quality System | ||
| ▲ Hunhu Hwekusimbisa Sisitimu | √ |
▲ Kudzora zvinyorwa | √ | |
▲ Validation System | √ | |
▲ Kudzidzisa System | √ | |
▲ Internal Audit Protocol | √ | |
▲ Suppler Audit System | √ | |
▲ Equipment Facilities System | √ | |
▲ Material Control System | √ | |
▲ Kugadzira Kudzora System | √ | |
▲ Packaging Labeling System | √ | |
▲ Laboratory Control System | √ | |
▲ Verification Validation System | √ | |
▲ Regulatory Affairs System | √ | |
Dzora Manyuko Akazara uye Maitiro | ||
Yakanyatso kudzora zvese mbishi zvinhu, zvekushandisa uye kurongedza zvinhu. Preferred mbishi zvinhu uye zvishongedzo uye kurongedza zvinhu mupi neUS nhamba yeDMF. |
Vanoverengeka vatengesi vezvinhu zvakasvibiswa sevimbiso yekugovera.Strong Cooperative Institutions kutsigiraInstitute of botany/Institution of microbiology/Academy of Science and Technology/University