Magaca alaabta:β-NADPH
Magac kale:β-NADPH|beta-Nicotinamide adenine dinucleotide 2′-fosfate waxay hoos u dhigtay tetrasodium hydrate
La mid ah: beta-NADPH; 2′- NADPH hydrate; Coenzyme II waxay hoos u dhigtay cusbada tetrasodium; Dihydronicotinamide adenine dinucleotide phosphate tetrasodium cusbo; NADPH Na4; TPNH2 Na4; Triphosphopyridine nucleotide waxay hoos u dhigtay milixda tetrasodium
CAS No:2646-71-1
Lambarka EINECS:220-163-3
daahirnimo:≥98%
Heerkulka Kaydinta: -20°C
Muuqaal: Caddaan ilaa budo huruud ah
Sharaxaada Alaabta: β-NADPH (β-Nicotinamide Adenine Dinucleotide Phosphate, Foomka Tetrasodium Salt oo La dhimay)
Lambarka CAS: 2646-71-1
Qaacidada Molecular: C21H26N7Na4O17P3
Miisaanka Molecular: 833.35
Daahirsanaanta: ≥97% (HPLC)
Muuqaal: Caddaan ilaa budo cad-cad
Solubility: Si xor ah ugu milmay biyaha (50 mg/mL)
Tilmaamaha Muhiimka ah
- Nadaafadda Sare & Deganaanshaha
- Synthetically laga soo qaatay ≥97% nadiif ah, hubinta waxqabadka la isku halayn karo ee qiimaynta bayoolaji ee xasaasiga ah.
- Deggan -20°C marka la kaydiyo engegan lagana ilaaliyo iftiinka; xalalka horay loo sii diyaariyay waa la daadin karaa waxaana lagu kaydin karaa -20 ° C ilaa 1-2 bilood.
- Codsiyada ballaaran
- Ku-deeqaha Electron: Wuxuu u adeegaa sidii cofactor ee oxidoreductases, oo ay ku jiraan nitric oxide synthase iyo thioredoxin reductase.
- Biosynthesis: Aad bay muhiim ugu tahay xuubka, kolestaroolka, iyo isku dhafka nucleotide iyada oo loo marayo falcelinta wax-ka-yar.
- Difaaca Antioxidant: Waxay unugyada ka ilaalisaa noocyada oksijiinta falcelinta (ROS) iyadoo ilaalinaysa heerarka glutathione oo hoos u dhacay.
- Dib-u-eegeyaasha ogaanshaha: Waxaa loo adeegsaday imtixaannada enzymatic ee cilmi-baarista bukaan-socodka iyo horumarinta dawooyinka.
- Guryaha indhaha
- UV nuugista ugu sarreysa ee 260 nm (ε = 15.0 × 10³ L·mol⁻¹·cm⁻¹) iyo 340 nm (ε = 6.3 × 10³ L·mol⁻¹·cm⁻¹), oo ku habboon cabbirka spectrophotometric.
Kaydinta & Wax ka qabashada
- Kaydinta:
- Muddada gaaban: 2-8 ° C ee hawo-mareenka, weelasha iftiinka-ilaaliye ah.
- Muddada dheer: -20 ° C xaaladaha qallalan; iska ilaali wareegyada barafaysan .
- Diyaarinta:
- Ku soo celi kaydka alkaline (tusaale, 10 mM NaOH) si loo helo xasillooni ugu fican; Xalalka acidic waxay hoos u dhigaan NADPH si degdeg ah .
- Centrifuge lyophilized budada ah ee 2,000-10,000 × g ka hor inta aan la isticmaalin si loo hubiyo in ay isku mid yihiin.
Badbaadada & U Hogaansanaanta
- Isticmaalka loogu talagalay: Ujeeddooyin cilmi-baaris oo keliya. Maaha ogaanshaha, daaweynta, ama isticmaalka bini'aadamka.
- Taxaddarrada Badbaadada:
- Xiro jaakadaha shaybaadhka, galoofyada, iyo ilaalinta indhaha inta aad gacanta ku hayso.
- Aan khatar ahayn marka loo eego qawaaniinta gaadiidka caadiga ah (Qaybta UN NONH) .
Waa maxay sababta aan u dooranay β-NADPH?
- Heerarka Caalamiga ah: Waxa lagu soo saaray FSSC22000 iyo hababka xakamaynta tayada ee FDA
- Taageerada Farsamada: Waxaa taageeray iskaashiga hay'adaha hormuudka ah (tusaale, Jaamacadda Harvard, CAS) ee codsiyada goynta.
- Baakadaha gaarka ah: Waxaa lagu heli karaa 10 mg ilaa 1 g tiro si loogu wajaho baahiyaha tijaabada ee kala duwan.
Erayada furaha: β-NADPH, Coenzyme II la dhimay,CAS 2646-71-1, ku deeqaha elektarooniga ah, oxidoreductase cofactor, NADPH tetrasodium cusbo
