Magaca badeecada:Budada Gamma-glutamylcysteine
La mid ah: gamma-L-Glutamyl-L-cysteine, γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, GGC,(2S)-2-Amino-5-{[(1R)-1-carboxy-2- sulfanylethyl]amino}-5-oxopentanoic acid, cysteine, Continal-G
Qaacidada Molecular: C8H14N2O5S
Miisaanka Molecular: 250.27
Lambarka CAS: 686-58-8
Muuqashada/midabka: Budada crystalline cad
Solubility: Biyo ku milmay
Faa'iidooyinka: horudhaca glutathione
Gamma-glutamylcysteinewaa dipeptide waana horudhaca ugu dhaqsaha badan ee tripeptideglutathione (GSH).Gamma glutamylcysteine wuxuu leeyahay magacyo kale oo badan, sida γ -L-Glutamyl-L-cysteine, γ-glutamylcysteine, ama GGC oo kooban.
Gamma Glutamylcysteine waa budo crystalline cad oo leh caanaha molecular C8H14N2O5S waxayna leedahay miisaan kelli ah 250.27.Lambarka CAS ee xaruntan waa 686-58-8.
Gamma-glutamylcysteine VS Glutathione
Unugyada Gamma glutamylcysteine waa horudhaca glutathione.Waxay geli kartaa unugyada waxayna u rogi kartaa wax badan oo ka mid ah antioxidant-kan xoogga leh marka gudaha ay ku jirto enzyme isku-darka labaad ee loo yaqaan 'glutathione synthetase'.Tani waxay ku siin kartaa xoogaa nafis ah cadaadiska oksaydhiyaha haddii ay ka caawiso unugyada GCL daciifka ah inay dib u soo kabtaan oo ay dib u helaan shaqadii caadiga ahayd mar kale dagaalka joogtada ah ee nolosha ee ka dhanka ah xagjirka xorta ah ee waxyeelleeya dhammaan unugyada caafimaadka qaba waqti ka dib!
Feejignaanta intracellular gamma-glutamylcysteine (GGC) guud ahaan waa mid hooseeya sababtoo ah waxay la falgashaa glycine si ay u sameyso glutathione.Habkani si dhakhso ah ayuu u dhacaa, maadaama GGC uu haysto nus-nolosha 20 daqiiqo marka uu ku jiro cytoplasm.
Si kastaba ha ahaatee, kaabista afka iyo duridda ee glutathione ma awoodo inay kordhiso glutathione-ka gacanta ee bini'aadamka.Wareega glutathione ma geli karto unugyo dhawrsan oo waa in marka hore loo kala qaybiyaa saddexda qaybood ee amino acid, glutamate, cysteine, iyo glycine.Farqiga weyni waxa uu ka dhigan yahay in ay jirto xoog-ururin aan laga gudbi karin oo u dhexeeya deegaanka ka baxsan gacanta iyo unugyada, kaas oo mamnuucaya isku-darka unugyada ka baxsan.Gamma-glutamylcysteine waxaa laga yaabaa inuu yahay ciyaaryahan fure u ah qaadista GSH ee noolaha unugyada badan.
Gamma-glutamylcysteine VS NAC (N-acetylcysteine)
Gamma-Glutamylcysteine waa unug siiya unugyada GGC, oo ay u baahan yihiin inay soo saaraan Glutathione.Kaabayaasha kale sida NAC ama glutathione ma samayn karaan tan gabi ahaanba.
Habka ficilka ee Gamma-glutamylcysteine
Sidee GGC u shaqeysaa?Nidaamku waa mid fudud: waxay awood u leedahay inay kordhiso heerarka glutathione si dhakhso ah.Glutathione waa amino acid lagama maarmaan ah oo qabta hawlo badan oo jidhka ah kana ilaaliya sunta.Glutathione waxay ka qaybqaataa sidii cofactor mid ka mid ah saddexda enzymes ee beddelaya leukotrienes si ay uga caawiso yaraynta calaamadaha neefta, waxay caawisaa sii deynta walxaha sunta ah ee unugyada si ay uga soo baxaan xaniinyaha saxarada ama kaadida, hagaajinta dhaawaca DNA ee ay sababaan xagjirrada xorta ah ee leh sifooyinka antioxidant, waxay buuxisaa glutamine ka dib jimicsigu waxay wanaajisaa shaqada difaaca iyada oo loo marayo soo saarista unugyada difaaca jirka sida IgA (immunoglobulin A) kaas oo naga caawiya inuu naga ilaaliyo caabuqa neefsashada inta lagu jiro xilliga qaboobaha marka aan aad ugu nugul nahay - waxaas oo dhan iyada oo door muhiim ah ka ciyaaraysa meelo kale sida nidaaminta dheef-shiid kiimikaadka!
Habka Wax-soo-saarka Gamma-glutamylcysteine
Wax-soo-saarka bayooloji ee halsano sannadihii la soo dhaafay midna si guul leh loogama ganacsan.Habka biocatalytic ee Gamma-glutamylcysteine ayaa si guul leh loogu xayeysiiyay warshadda Sayniska Cima.GGC hadda waxaa laga heli karaa kaab ahaan gudaha Maraykanka iyadoo hoos imanaysa magaca ganacsiga ee Glyteine iyo Continal-G.
Faa'iidooyinka Gamma-glutamylcysteine
Gamma-glutamylcysteine waxaa la caddeeyey inuu kor u qaado heerarka glutathione-ka gacanta 90 daqiiqo gudahood.Glutathione, difaaca aasaasiga ah ee jirka ee ka hortagga xagjirka xorta ah, ayaa loo yaqaanaa inay gacan ka geysato dhimista cadaadiska oksaydhiyeyaasha ee ka yimaada xagjirrada xorta ah iyo taageeridda hawlo kala duwan oo jidhka ah oo ay ku jiraan sun-saarid.
- Taageer beerka, maskaxda, iyo caafimaadka difaaca
- Antioxidant awood leh iyo detoxifier
Glutathione waxay muhiim u tahay sunta jirkaaga waxayna taageertaa shaqada beerka, kelyaha, mareenka GI, iyo xiidmaha.Glutathione waxa ay door muhiim ah ka ciyaartaa ilaalinta hababka jidhku si fiican ugu shaqaynayaan iyada oo ka caawinaysa waddooyinka sun-saarista oo ay ku jiraan kuwa laga helo dhiigga gudihisa iyo sidoo kale xubnaha waaweyn sida kelyaha, marinka GI, ama xiidmaha. - Kor u qaad tamarta, diiradda, iyo xoogga saarista
- Nafaqada ciyaaraha
Heerarka Glutathione waxay kaa caawin karaan inaad qabato sida ugu fiican, caafimaad qab, oo si fudud u soo kabsato.Hubi inaad kordhiso glutathione iyada oo loo marayo cunto ama kabitaan si unugyada jidhku u shaqeeyaan si wanaagsan oo hufan si ay u awoodaan inay hoos u dhigaan wakhtiga soo kabashada ka dib jimicsiga.
Saamaynnada Gamma-glutamylcysteine
Gamma-glutamylcysteine wuxuu ku cusub yahay suuqa kaabista, mana jiraan waxyeelo halis ah oo la soo sheegay weli.Waa in guud ahaan si badbaado leh loo qaato iyadoo loo eegayo talada dhakhtarkaaga.
Qiyaasta Gamma-glutamylcysteine
Qiimaynta badbaadada ee cusbada sodium ee GGC ee jiirka ayaa muujisay in afka laga maamulo (gavage) GGC aanay si ba'an ugu suntan xadka kaliya ee 2000 mg/kg, taas oo muujinaysa wax saameyn ah oo xun kadib qaadashada maalinlaha ah ee soo noqnoqda muddo 90 maalmood ah.
