Tilmaamaha Alaabta Dhamaystiran:Kojic Acid Dipalmitate98% (HPLC) ee Maqaarka Cadaynta iyo Ka-hortagga Gabowga
1. HordhacKojic Acid Dipalmitate
Kojic acidDipalmitate (KAD, CAS79725-98-7) waa soosaar liposoluble oo ah kojic acid, oo caan ku ah xasiloonideeda sare, waxtarkeeda, iyo badbaadada qaababka qurxinta. Sida jiilka soo socda ee tyrosinase inhibitor, waxay si wax ku ool ah u yareysaa isku-dhafka melanin, waxay wax ka qabtaa hyperpigmentation, waxayna kor u qaadaa xitaa midabka maqaarka. Iyada oo nadiif ah 98% ay xaqiijisay HPLC, walaxdaani waxay ku habboon tahay alaabada daryeelka maqaarka ee dhamaadka-sare ee bartilmaameedka ah dhibco madow, melasma, iyo midab da'da la xidhiidha.
Codsiyada Muhiimka ah:
- Iftiinka Maqaarka: Waxay joojisaa wax soo saarka melanin iyadoo xannibaysa dhaqdhaqaaqa tyrosinase, oo ka sarreeya kojic acid dhaqameed.
- Ka-hortagga gabowga: Waxay yaraynaysaa khadadka wanaagsan waxayna wanaajisaa barti maqaarka iyada oo loo marayo sifooyinka antioxidant.
- Qaababka shaqada badan: La jaan qaadaya serums, kiriimyada, muraayadaha qorraxda, iyo alaabada ka hortagga finanka.
2. Kiimikada iyo Qalabka Jirka
Qaacidada unugyada: C₃₈H₆₆O₆
Miisaanka Molecular: 618.93 g/mol
Muuqaal: Caddaan ilaa budo crystalline ah
Meesha dhalaalaysa: 92-95°C
Solubility: Saliid-milmi (ku habboon esters, saliidaha macdanta, iyo khamriga) .
Faa'iidooyinka xasilloonida:
- Range pH: Deggan pH 4-9, ku habboon qaabab kala duwan.
- Iska caabbinta kulaylka/Iftiinka: Ma jiro oksaydhyo ama midabayn kulaylka ama soo-gaadhista UV, si ka duwan kojic acid.
- Iska caabinta Birta Ion: Waxay ka fogaataa chelation, hubinta xasilloonida midabka muddada dheer.
3. Farsamaynta Ficilka
KAD waxay ku shaqaysaa hab laba hab:
- Kahortagga Tyrosinase: Wuxuu xannibaa goobta firfircoonida enzyme-ka, isagoo ka hortagaya isku-dhafka melanin. Daraasaduhu waxay muujinayaan waxtarka 80% ka sarreeya kojic acid.
- Siidaynta la xakameeyey: Esterases maqaarka ku jira hydrolyze KAD galay kojic acid firfircoon, hubinta depigmentation joogto ah.
Faa'iidooyinka caafimaad:
- Waxay yaraysaa dhibcaha da'da, hyperpigmentation post-inflammatory (PIH), iyo melasma.
- Waxay kordhisaa waxtarka muraayadda qorraxda iyadoo la yareynayo melanogenesis-ka UV-ku keeno.
4. Faa'iidooyinku way dhaafeenKojic acid
| Halbeegga | Kojic acid | Kojic Acid Dipalmitate |
|---|---|---|
| Xasilooni | Oxidizes si fudud, huruud isu beddela | Kuleyl/iftiin xasiloon, midab ma leh |
| Solubility | Biyo-milmi kara | Saliid-milmi kara, maqaarka oo si fiican u nuugaya |
| Khatarta Xanaaq | Dhexdhexaad (pH-xasaasi ah) | Hooseeyo (u jilicsan maqaarka xasaasiga ah) |
| Dabacsanaanta qaabaynta | Ku xaddidan pH acidic | La jaan qaada pH 4-9 |
5. Tilmaamaha samaynta
Qiyaasta lagu taliyay: 1-5% (3-5% cadaynta degdega ah) .
Isku-dhafka Tallaabo-tallaabo:
- Diyaarinta Wajiga Saliida: Ku mil KAD gudaha isopropyl myristate/palmitate at 80°C ilaa 5 daqiiqo.
- Emulsification: Isku qas wajiga saliidda leh wejiga aqueous at 70 ° C, isku mid ah 10 daqiiqo.
- Hagaajinta pH: Ku ilaali pH 4-7 xasilloonida ugu fican.
Tusaalaha Formula (Serum-caddaan):
| Walaxda | Boqolkiiba |
|---|---|
| Kojic Acid Dipalmitate | 3.0% |
| Niacinamide | 5.0% |
| Hyaluronic acid | 2.0% |
| Vitamin E | 1.0% |
| Daawooyinka ilaaliya | qs |
6. Badbaadada iyo u hoggaansanaanta
- Kuwa aan Kansarka lahayn: Hay'adaha sharciyeynta (EU, FDA, China CFDA) ayaa u oggolaaday KAD isticmaalka qurxinta. Daraasaduhu waxay xaqiijinayaan inaysan jirin khatar kansar ah .
- Shahaadooyinka: ISO 9001, REACH, iyo Xalaal/Kosher fursadaha la heli karo.
- Eco-Friendly: Waxa laga soo xigtay non-GMO, alaabta ceeriin ee bilaa naxariista ah.
7. Baakadaha iyo Saadka
Cabirka la heli karo: 1 kg, 5 kg, 25 kg (la beddeli karo)
Kaydinta: Qabow, deegaan qallalan (<25°C), oo laga ilaaliyo iftiinka.
Dhoofinta Caalamiga ah: DHL/FedEx ee muunado (3-7 maalmood), xamuulka badda ee dalabaadka badan (7-20 maalmood) .
8. Waa maxay sababta aan u dooranay KAD 98% (HPLC)?
- Dammaanad-qaadka Nadiifinta: 98% waxaa xaqiijiyay HPLC, iyadoo COA iyo MSDS la bixiyay.
- Taageerada R&D: La-talin farsamo oo bilaash ah iyo tijaabo muunad ah.
- Isha Joogta ah: La shaqaynta alaab-qeybiyeyaasha ECOCERT-shahaadad siisay.
9. FAQs
S: KAD badbaado ma u tahay midabada maqaarka madow?
J: Haa. Muuqaalkeeda xanaaqa hooseeya ayaa ka dhigaya mid ku habboon noocyada maqaarka ee Fitzpatrick IV-VI.
S: KAD ma bedeli karaa hydroquinone?
J: Dhab ahaantii. KAD waxay bixisaa waxtar la mid ah oo aan lahayn cytotoxicity.
Erayada furaha: Kojic Acid Dipalmitate, Wakiilka Maqaarka Cadaynta, Inhibitor Tyrosinase, Dhimista Melanin, Hagaha Qaabaynta Quruxda, Daawaynta Dhiigbaxa, Walaxda Cadaynta Deggan.
Sharaxaad: Soo hel sayniska ka dambeeya Kojic Acid Dipalmitate 98% (HPLC) — maqaarka dhalaalaysa oo deggan, aan xanaaqin. Baro talooyinka habaynta, habka, iyo xogta badbaadada ee suuqyada EU/US
