Paclitaxel waa unug monomer diterpenoid ah oo laga soo saaro jilif dhirta dabiiciga ah ee Paclitaxel, waa nooc ka mid ah dheef-shiid kiimikaad sare oo adag, hadda la fahamsan yahay kaliya daroogada ayaa kor u qaadi karta polymerization microtubule iyo xasiloonida microtubules ayaa la isku daray.Raadinta Isotope ayaa muujisay taaspaclitaxelwaxay ku xidhnayd oo kaliya in lagu xidho microtubules-ka polymerized, ee kuma xidhna tubbada polymerized laba.Xiriirka gacantapaclitaxelKa dib markii la ururiyo tiro badan oo ah microtubules unugyada, kuwaas oo farageliya ururinta microtubule ee hawlaha kala duwan ee gacanta, gaar ahaan qaybta unuggu waxay joojiyaan mitosis, oo xannibaya qaybta unugyada caadiga ah.
Magaca Alaabta:Paclitaxel99.0%
Foom: Budada crystalline cad
cayiman: 99%
Habka tijaabada : HPLC
Lambarka CAS: 33069-62-4
Qaacidada unugyada:C47H51NO14
Barta Karsan：957.115 °C at 760 mmHg
Miisaanka Molecular: 853.91
Xaalada GMO:GMO Bilaash
Xirmooyinka: 25kgs durbaannada fiber-ka
Kaydinta: Weelka ha furin meel qabow oo qalalan, ka fogow iftiinka xooggan
Life Life:24 bilood laga bilaabo taariikhda wax soo saarka
Shaqada:
1.Paclitaxel waxaa inta badan lagu dabaqaa kansarka ugxansidaha iyo kansarka naasaha, kansarka sanbabada, kansarka mindhicirka, melanoma, kansarka madaxa iyo qoorta, lymphoma, iyo waxa ay sidoo kale saameyn gaar ah ku leedahay burooyinka maskaxda.
2.It waa daawooyinka xasiloonida kuwaas oo kor u qaadi kara polymerization microtubule iyo polymerization microtubule.
3.Waxaa lagu ururin doonaa tiro badan oo microtubules ah oo ku jira unugyada ka dib marka la soo bandhigo paclitaxel, ururinta microtubules waxay faragelisaa hawlaha unugyada, gaar ahaan, qaybinta unugyada la joojiyay ee mitosis, xannibaya qaybta unugyada caadiga ah.
Codsiga:
Loo adeegsaday daraasadda qaab-dhismeedka iyo shaqada microtubles-ka ee tubulin.Paclitaxel hadda waxaa loo isticmaalaa in lagu daweeyo bukaanada qaba sambabada, ugxansidaha, kansarka naasaha, kansarka madaxa iyo qoorta, iyo qaababka hore ee sarcoma Kaposi.Paclitaxel waa ka hortag mitotic ah oo loo isticmaalo daawaynta kiimikaad ee kansarka.
| Macluumaad dheeraad ah oo ku saabsan TRB | ||
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| v Nidaamka Hubinta Tayada | √ |
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| Machadyo iskaashi oo xooggan si ay u taageeraan | ||
| Machadka dhirta/machadka microbiology/Academy of Science and Technology/Jaamacad | ||
