Sida caadiga ah waxaan si fudud u buuxin karnaa macaamiisheena ixtiraamka leh oo leh tayo sare oo aad u wanaagsan, qiimo aad u wanaagsan iyo taageero aad u fiican sababtoo ah waxaan ahayn khabiir badan oo aad u dadaal badan oo aan u samayno qaab kharash-ool ah oo loogu talagalay Naqshadeynta Caanka ah ee Shiinaha CAS 1094 -61-7 99% NmnNicotinamide Mononucleotide budada, Waxaan soo dhaweyneynaa macaamiisha cusub iyo kuwa duugoobay ee dhammaan qaybaha kala duwan ee nolol maalmeedka si ay nooga hadlaan ururada ganacsiga mustaqbalka iyo guusha wadajirka ah!
Sida caadiga ah waxaan si fudud u buuxin karnaa macaamiisheena sharafta leh oo leh tayo sare oo aad u wanaagsan, qiimo aad u wanaagsan iyo taageero aad u fiican sababtoo ah waxaan ahayn khabiir badan oo aad u dadaal badan oo aan u samayno hab kharash-ool ahShiinaha Nmn Powder, Walxaha lagu caddeeyo, Alaabooyinka iyo xalalka waxay leeyihiin sumcad wanaagsan oo leh qiimo tartan, abuurista gaarka ah, hogaaminaya isbeddellada warshadaha.Shirkaddu waxay ku adkaysanaysaa mabda'a fikradda guul-guulaysiga, waxay samaysay shabakad iibka caalamiga ah iyo shabakadda adeegga iibka kadib.
Nikotinamide mononucleotide bulk bulk ah
Magaca alaabta:Nikotinamide mononucleotide budada ah
La mid ah: NMNβ-Nicotinamide Mononucleotide, beta-Nicotinamide Mononucleotide
Lambarka CAS: 1094-61-7
Tilmaamaha: 99% min
Qaanuunka molecular: C11H15N2O8P
Miisaanka Molecular: 334.221 g/mol
Xidhmada: 1kg/bac, 25kg/durbaan
Waa maxay Nicotinamide Mononucleotide?
Nicotinamide mononucleotide, oo loo soo gaabiyo sidaNMN, wuxuu leeyahay magacyada soo socda:
β-NMN, BETA-Nicotinamide Mononucleotide;
BETA-NMN;BETA-NICOTINAMIDE MONOUCLEOTIDE;
BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE;
NICOTINAMIDE-1-IUM-1-BETA-D-RIBOFURANOSIDE 5′-PHOSPHATE;NICOTINAMIDE RIBOTIDE;
NICOTINAMIDE MONOUCLEOTIDE
NMN waxa ay ka dhex jirtaa noole kala duwan oo ay ku jiraan bini'aadamka waana xarun lagama maarmaan u ah ilaalinta hawlaha jidhka.NMN dib ayaa loo isticmaalaa ka dib markii uu jidhku dheef-shiid kiimikaad sameeyay, fitamiin B3 ee cuntada ayaa waliba soo saari kara NMN.
Kahor intaanan fahmin nicotinamide mononucleotide, waxaan u baahanahay inaan ogaano waxa ay tahay.Nicotinamide mononucleotide (NMN) waa horudhac lama huraan u ah NAD+, iyo NAD+ waa hab muhiim u ah hagaajinta unugyada aadanaha.Marka bani'aadamku ay ku jiraan dhallaanka iyo carruurta yaryar, korriinkooda iyo korriimadoodu aad bay u degdegayaan, marka ay koraan da'da, jidhka bini'aadamka ayaa si tartiib tartiib ah hoos u dhacaya.Tusaalaha fudud waa sida kii hore;shil baad ku indho beelaysaa.Kuuskuuskii waa la garaacay, kaaga darane, dhaawacyo halis ah ayaa soo gaaray.Habka gabowga ee unugyada bini'aadamka, qadarka NAD + aad ayuu u yarayn doonaa marka la barbardhigo wixii la soo dhaafay sababtoo ah dheef-shiid kiimikaadka iyo jidhka laftiisa.
Nicotinamide mononucleotide waa qayb muhiim ah oo ka mid ah noolaynta aadanaha.Saynis yahanada adduunka ayaa ogaaday in nicotinamide mononucleotide ay saameyn gaar ah ku leedahay gabowga.Cilmi baaris qoto dheer, furaha nicotinamide mononucleotide waa in uu yahay horudhaca NAD +, kaas oo u beddeli doona NAD +, kaabi doona qodobka hagaajinta unugyada unugyada bini'aadamka, iska caabinta habka gabowga, oo ay u helaan fursad ay dib ugu bilaabaan shaqada dib u kobcinta unugga, kaas oo ah shaqada fidinta nolosha ee nicotinamide mononucleotide.
Nicotinamide mononucleotide si dabiici ah ayay ugu jirtaa unug kasta oo jidhkeena ah waana qayb muhiim ah oo ka mid ah is hagaajinta jidhka.Waa dheef-shiid kiimikaad loogu talagalay ilaalinta NAD + biosynthesis caadiga ah, walaxdani waxay nidaamin kartaa physiology inta lagu jiro wareegga jidhka, iyo pathology gaar ah.Waxay ka ciyaartaa door muhiim ah shaqada unugga.
Kaabayaasha ka kooban NMN
Waxaa jira alaab badan oo dheeri ah oo NMN ah oo hadda la iibinayo.Qaar ayaa caan ka ah isticmaalayaasha dhamaadka, sida NMN Pure, Ultra NMN, iwm. ee Amazon iyo dukaamada kale ee internetka.
Noocyada qaarkood waxay ku jiraan NNN oo keliya, qaarna waxay la socdaan maaddooyinka kale ee firfircoon ee ka-hortagga gabowga, sida resveratrol, pterostilbene, soosaar xididka, iwm.
Labada foomamka kaabsulka iyo kaniiniga waa la heli karaa, hoos waxaa ah xaqiiqooyinka kaabsalka NMN ee qaar ka mid ah sumadaha NMN:
125mg waxay u muuqataa inay tahay qiyaasta caanka ah ee inta badan supplements NMN, in kasta oo qaar ka mid ah ay qoraan 260mg halkii kaabsal calaamadahooda oo leh cabbirka adeegga ee 2 kaabsoosha ama kiniinnada maalin kasta.Ma jiro qiyaas rasmi ah oo lagu taliyay hadda.
Farsamaynta ficilka nicotinamide mononucleotide
Nicotinamide mononucleotide waxaa loo beddelaa "nicotinamide adenine dinucleotide (NAD)" walax lagama maarmaan u ah dheef-shiid kiimikaadka tamarta ee jirka.Tijaabada jiirka, ayaa lagu xaqiijiyay in nicotinamide mononucleotide uu ka hawlgelin karo hidde-sidayaasha loo yaqaanno acetylase ee jidhka, taas oo samaynaysa saamayn ay ka mid tahay cimriga oo dheereeya iyo daawaynta macaanka.NAD waa walax uu soo saari karo jidhka bini'aadamka.Daraasaduhu waxay muujiyeen in maadada NAD ee jirku ay hoos u dhacdo da'da.
Korodhka bararka ee la xidhiidha gabowga ayaa wax u dhimi kara awoodda jidhka ee soo saarista NMN, taas oo iyaduna keenta hoos u dhaca NAD.
NMN waa walax horudhac ah oo ah koenzyme NAD + ee muhiimka ah ee jirka.Nicotinamide mononucleotide waa door muhiim ah oo ka mid ah wax soo saarka tamarta unugyada bini'aadamka, waxayna ku lug leedahay isku-darka NAD + intracellular (nicotinamide adenine dinucleotide, coenzyme loogu talagalay beddelka tamarta unugyada).
NMN waxaa si rasmi ah loogu aqoonsaday inay tahay walaxda dabiiciga ah ee ugu horreysa adduunka oo lagu xaqiijiyay tijaabooyin saynis ah oo adag si si wax ku ool ah loogu beddelo oo dib loogu dhigo gabowga loona dheereeyo nolosha.
2017, cilmi-baaristu waxay muujisay in NMN ay daweyn karto NR iyo NMN ataxia, iyo NR ma beddeleyso dhaqdhaqaaqa SIRT3 mana wanaajiso shaqada wadnaha.
NAD + sahaydu ma istaagi doonto - way sii socon doontaa in la isticmaalo oo la buuxiyo, iyo dhammaan barkada NAD + waxay rogaan 2-4 jeer maalintii.
Wareeggani wuxuu maraa dariiqyada hagaajinta, kaas oo enzyme Nampt uu kiciyo NAM ilaa NMN ka dibna metabolizes NAD +.Nampt waa tallaabada xadka xawaaraha ee habka kalluumeysiga.
Nicotinamide Mononucleotide VS.Nikotinamide Riboside
Maalmahan, dunidu waxay hodan ku tahay cilmi-baarisyo kala duwan oo NR ah, iyo tijaabada jidhka bini'aadamka ayaa natiijada NR ee xogta aragtida ka dhigaysa mid ka fiican NMN.Si kastaba ha ahaatee, daraasaduhu waxay muujiyeen in NR uu bilaabo inuu ka shaqeeyo jidhka bini'aadamka oo uu weli u baahan yahay inuu waayo-aragnimo u yeesho muddo.Furaha ayaa ah in NR iyo NMN labaduba ay yihiin horudhac NAD +, halka Nicotinamide Riboside (NR) ay tahay horudhac NMN iyo NAD +, markaa NR ayaa isbedeleysa.Waxay qaadataa wakhti ka hor NAD +.Marka la barbar dhigo saameynta degdega ah ee NMN, 15ka daqiiqo ee NR waa faraq weyn.
Waxaa laga arki karaa jaantuska meertada sare in NAMPT ay tahay arrin muhim ah oo xaddidaysa jiilka NMN.Marka da'du korodho, jidhka bini'aadamku ma rabo inuu yaraado, laakiin waxqabadka enzyme ee NAMPT ayaa hoos u dhacaya marka tamarta iyo nafaqooyinka la bixiyo.Marka wareegga NAM la yareeyo, kaydka NAD+ si dabiici ah ayaa loo dhimay.
NR waxaa loo rogi karaa NMN ama NAM, iyadoo ku xiran doorka Nrk1 enzyme si loo go'aamiyo walaxda tayada isku midka ah ee NR ayaa soo saari doonta wax badan.Haddii loo rogo NAM, waxaa sidoo kale xaddiday enzyme NAMPT.Marka la barbar dhigo ficilka tooska ah ee NMN si loo dhaliyo NAD +, saamaynta qaddar siman ee NR ayaa si cad u daciiftay wax badan.
Maxaad u qaadan wayday NAD+?
NAD+ si toos ah looguma qaadi karo unugyada maamulka afka sababtoo ah miisaankiisa kelli ee xad dhaafka ah.Kaabista NAD+ waxa kaliya oo lagu gaaraa in la qaato miisaan yar oo NAD+ horudhac ah.
Si kastaba ha noqotee, NMN waxaa laga samayn karaa noocyo kala duwan oo badeecooyin ah, kuwaas oo noqon kara kaabsal, kiniinno, ama xitaa granules sababtoo ah dabeecadeeda milmay.milanka NMN ee biyaha waa 35mg/ml.
Dareenkan, NMN aad ayuu uga fiican yahay NAD+, oo si toos ah uga badan nicotinamide riboside.
Nikotinamide Mononucleotide faa'iidooyinka
Saamaynta ugu weyn ee NMN waa sida soo socota:
- anti-oxidation
- In la yareeyo hoos u dhaca jireed
- Dayactirka DNA
- Taageer saamaynta neuroprotective
- Hagaajinta shaqada wadnaha oo ilaali wadnaha
- Hagaajinta xaaladda bukaanka Alzheimers
Tilmaamaha ugu caansan ee NMN waa in ay beddeli karto gabowga oo ay dheerayn karto nolosha.
Nikotinamide Mononucleotide waxyeellooyin
Maaddaama NMN ay hadda samaynayso tijaabooyinka xayawaanka oo kaliya, tijaabooyin baaxad leh oo bini'aadmi ah wali ma aysan bilaaban, sidaa darteed saameynaha soo raaca ee la go'aamin karo wali ma cadda.Si kastaba ha noqotee, marka loo eego habka ficilka ee NMN, waxaa la qiyaasi karaa in bukaannada kansarku aysan u qaadan inta ugu badan ee suurtogalka ah.Sababtoo ah isbeddelka NMN wuxuu kor u qaadaa wax soo saarka NAD +, halka unugyada kansarku ay la qabsadaan dhaqdhaqaaqyada jireed ee gaabis ah, kororka dheef-shiid kiimikaadka ayaa kicin kara faafitaanka unugyada kansarka qaarkood.
Marka la isticmaalayo nicotinamide nucleoside supplements sida NMN, waxqabadka jimicsiga ayaa laga yaabaa in la saameeyo.Jiirarka, jiirarka lagu duray kaabayaasha NAD+ waxay muujiyeen waxqabad aad uga yar marka loo eego kooxdooda.
