Orukọ: CDP-CHOLINE, CITICOLINE
Orukọ kemikali: cytidine5'-diphosphatecholine
Fọọmu Molecular: C14H26N4O11P2
CAS: 987-78-0
Einecs NỌ:213-580-7
Iwọn agbekalẹ: 488.33
Apearance: Pa funfun lulú.
Mimo: 98%
Orukọ kemikali: cytidine5'-diphosphatecholine
Fọọmu Molecular: C14H26N4O11P2
CAS: 987-78-0
Einecs NỌ:213-580-7
Iwọn agbekalẹ: 488.33
Apearance: Pa funfun lulú.
Mimo: 98%
Citicoline (INN), ti a tun mọ ni cytidine diphosphate-choline (CDP-Choline) tabi cytidine 5'-diphosphocholine jẹ nootropic.O jẹ agbedemeji ni iran ti phosphatidylcholine lati choline.
Awọn ijinlẹ daba pe awọn afikun CDP-choline ṣe alekun awọn iwuwo olugba dopamine, ati daba pe afikun CDP-choline ṣe iranlọwọ lati yago fun ailagbara iranti ti o waye lati awọn ipo ayika ti ko dara.Iwadi alakoko ti rii pe awọn afikun citicoline ṣe iranlọwọ lati mu idojukọ pọ si ati agbara ọpọlọ ati pe o ṣee ṣe wulo ni itọju aipe aipe akiyesi.
Citicoline tun ti ṣe afihan lati gbe ACTH ga ni ominira lati awọn ipele CRH ati lati mu itusilẹ ti awọn homonu axis HPA miiran bii LH, FSH, GH ati TSH ni idahun si awọn ifosiwewe itusilẹ hypothalamic.Awọn ipa wọnyi lori awọn ipele homonu HPA le jẹ anfani fun diẹ ninu awọn ẹni-kọọkan ṣugbọn o le ni awọn ipa ti ko fẹ ninu awọn ti o ni awọn ipo iṣoogun ti o nfihan ACTH tabi hypersecretion cortisol pẹlu PCOS, iru àtọgbẹ II ati ailera aibanujẹ nla.
Awọn ijinlẹ daba pe awọn afikun CDP-choline ṣe alekun awọn iwuwo olugba dopamine, ati daba pe afikun CDP-choline ṣe iranlọwọ lati yago fun ailagbara iranti ti o waye lati awọn ipo ayika ti ko dara.Iwadi alakoko ti rii pe awọn afikun citicoline ṣe iranlọwọ lati mu idojukọ pọ si ati agbara ọpọlọ ati pe o ṣee ṣe wulo ni itọju aipe aipe akiyesi.
Citicoline tun ti ṣe afihan lati gbe ACTH ga ni ominira lati awọn ipele CRH ati lati mu itusilẹ ti awọn homonu axis HPA miiran bii LH, FSH, GH ati TSH ni idahun si awọn ifosiwewe itusilẹ hypothalamic.Awọn ipa wọnyi lori awọn ipele homonu HPA le jẹ anfani fun diẹ ninu awọn ẹni-kọọkan ṣugbọn o le ni awọn ipa ti ko fẹ ninu awọn ti o ni awọn ipo iṣoogun ti o nfihan ACTH tabi hypersecretion cortisol pẹlu PCOS, iru àtọgbẹ II ati ailera aibanujẹ nla.
Ijẹrisi ti Analysis
| ọja Alaye | |
| Orukọ ọja: | Citicoline(CDP-Choline) |
| CAS No.: | 987-78-0 |
| Ilana molikula: | C14H26N4O11P2 |
| Ipele No. | TRB-CDP-20190620 |
| Ọjọ MFG: | Oṣu Kẹfa ọjọ 20, 2019 |
| Nkan | Sipesifikesonu | Awọn abajade Idanwo |
| Awọn eroja ti nṣiṣe lọwọ | ||
| Ayẹwo (%Lori Ipilẹ Gbigbe) | 98.0% ~ 102.0% nipasẹ HPLC | 100.30% |
| Iṣakoso ti ara | ||
| Ifarahan | Fine crystalline Powder | Ibamu |
| Àwọ̀ | Funfun to Pa White | Ibamu |
| Idanimọ | NMR | Ibamu |
| PH | 2.5 ~ 3.5 | 3.3 |
| Isonu lori Gbigbe | 1.0% ti o pọju | 0.041% |
| Omi | 1.0% ti o pọju | 0.052% |
| 5'-CMP | NMT1.0% | 0.10% |
| Iṣakoso kemikali | ||
| Awọn irin ti o wuwo | NMT10PPM | Ibamu |
| Arsenic (As2O3) | NMT1PPM | Ibamu |
| Sulfate (SO4) | NMT 0.020% | Ibamu |
| Irin (Fe) | NMT10PPM | Ibamu |
| Kloride (Cl) | NMT 0.020% | Ibamu |
| Aloku ti o ku | Ipade EU/USP Standard | Ibamu |
| Microbiological Iṣakoso | ||
| Apapọ Awo kika | 10,00cfu / g Max | Ibamu |
| Iwukara & Mold | 100cfu/g o pọju | Ibamu |
| E.Coli | Odi/10g | Ibamu |
| Salmonella sp. | Odi/25g | Ibamu |
| Staph Aureus | Odi/10g | Ibamu |
| Pseudomonas aeruginosa | Odi/25g | Ibamu |
| Iṣakojọpọ ati Ibi ipamọ | ||
| Iṣakojọpọ | Pa ninu iwe-ilu.25Kg / Ilu 1Kg fun apo ṣiṣu | |
| Ibi ipamọ | Fipamọ sinu apoti ti o ni pipade daradara kuro lati ọrinrin ati oorun taara. | |
| Igbesi aye selifu | Ọdun 2 ti o ba ni edidi ati ti o fipamọ daradara. | |
| Alaye siwaju sii ti TRB | ||
| Regulation iwe eri | ||
| USFDA,CEP,KOSHER HALAL GMP ISO Awọn iwe-ẹri | ||
| Didara ti o gbẹkẹle | ||
| O fẹrẹ to ọdun 20, okeere awọn orilẹ-ede 40 ati awọn agbegbe, diẹ sii ju awọn ipele 2000 ti a ṣe nipasẹ TRB ko ni awọn iṣoro didara eyikeyi, ilana isọdọmọ alailẹgbẹ, aimọ ati iṣakoso mimọ pade USP, EP ati CP | ||
| Okeerẹ Didara System | ||
|
| ▲ Eto idaniloju Didara | √ |
| ▲ Iṣakoso iwe | √ | |
| ▲ Eto Afọwọsi | √ | |
| ▲ Eto Ikẹkọ | √ | |
| ▲ Ilana iṣayẹwo inu inu | √ | |
| ▲ Suppler Audit System | √ | |
| ▲ Eto Ohun elo Ohun elo | √ | |
| ▲ Eto Iṣakoso Ohun elo | √ | |
| ▲ Eto Iṣakoso iṣelọpọ | √ | |
| ▲ Packaging Labeling System | √ | |
| ▲ Eto Iṣakoso yàrá | √ | |
| ▲ Afọwọsi Eto | √ | |
| ▲ Regulatory Affairs System | √ | |
| Ṣakoso Gbogbo Awọn orisun ati Awọn ilana | ||
| Ti ṣakoso ni pipe gbogbo awọn ohun elo aise, awọn ẹya ẹrọ ati awọn ohun elo iṣakojọpọ.Awọn ohun elo aise ti o fẹ ati awọn ẹya ẹrọ ati olupese awọn ohun elo apoti pẹlu nọmba DMF AMẸRIKA.Ọpọlọpọ awọn olupese ohun elo aise bi idaniloju ipese. | ||
| Awọn ile-iṣẹ ifowosowopo ti o lagbara lati ṣe atilẹyin | ||
| Institute of Botany/Ile-ẹkọ ti microbiology/Academy of Science and Technology/University | ||
