I-S-adenosyl-L-methionine disulfate tosylate

Igama Lomkhiqizo:S-adenosyl-L-methionine disulfate tosylate

Elinye Igama:Ademetionine disulfate tosylate; I-AdeMethionine Disulfate Tosylate; I-SAM-TAdemetionine disulfate tosylate; I-Ademetionine Disulfate Tosylate (SAMe)

Inombolo ye-CAS:97540-22-2

Isivivinyo: 98%Miniz

Umbala: Impushana emhlophe

Isimo se-GMO:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

I-SAMe inikela ngeqembu le-methyl ngezinhlobo ze-biosynthesis yamaprotheni, ama-neurotransmitters, ama-nucleic nama-nucleic acid. Lokhu kwenzeka ekuphenduleni okuningi kwe-enzymatic transmethylation.

I-Adenosylmethionine (SAMe) iyinhlanganisela eyenzeka ngokwemvelo etholakala cishe kuzo zonke izicubu noketshezi emzimbeni. Ihilelekile ezinqubweni eziningi ezibalulekile. I-SAMe idlala indima esimisweni sokuzivikela komzimba, igcina ulwelwesi lwamangqamuzana, futhi isiza ukukhiqiza nokudiliza amakhemikhali obuchopho, njenge-serotonin, i-melatonin, ne-dopamine.

Ukuthatha i-SAMe ngomlomo kubonakala kusebenza mayelana ne-ibuprofen nezinye izidakamizwa ezifanayo zokunciphisa izimpawu ze-osteoarthritis. Kodwa abantu abaningi badinga ukuthatha i-SAMe isikhathi esingangenyanga ngaphambi kokuba bazizwe bengcono.

Abantu ngokuvamile basebenzisa i-SAMe ukwelapha ukudangala, i-osteoarthritis nesifo sesibindi. Kodwa-ke, i-SAMe ingaphinde ihlanganyele nemithi elwa nokucindezeleka.

Ingase ikhiphe ubuthi izinto eziyingozi emzimbeni. Lezi zihlanganisa izinsimbi ezisindayo. Kungase futhi kuvimbele ukulimala kwesibindi kubuthi be-acetaminophen futhi kusize ukuvimbela ukufakwa kwamafutha esibindi sakho. Kungase futhi kusize ekudambiseni ukukhathala futhi kwehlise ingcuphe ye-balding ngaphambi kwesikhathi.

Emaseli e-eukaryotic, i-SAM isebenza njengomlawuli wezinqubo ezihlukahlukene ezihlanganisa i-DNA, i-tRNA, ne-rRNA methylation; ukuphendula komzimba; i-amino acid metabolism; transsulfuration; futhi nokuningi. Ezitshalweni, i-SAM ibalulekile ku-biosynthesis ye-ethylene, i-hormone yezitshalo ebalulekile kanye ne-molecule ekhombisayo.

I-T-Adenosylmethionine (SAMe) iyinhlanganisela eyenzeka ngokwemvelo etholakala cishe kuzo zonke izicubu noketshezi emzimbeni. Ihilelekile ezinqubweni eziningi ezibalulekile. I-SAMe idlala indima esimisweni sokuzivikela komzimba, igcina ulwelwesi lwamangqamuzana, futhi isiza ukukhiqiza nokudiliza amakhemikhali obuchopho, njenge-serotonin, i-melatonin, ne-dopamine.

Umsebenzi

I-Transmethylation

I-SAMe ingumnikeli we-methyl obaluleke kakhulu emzimbeni, futhi okungenani ukusabela okuhlukile kwe-methyl transferase okutholakele kudinga i-SA M njengomnikezeli we-methyl. I-SAM isetshenziselwa i-biosynthesis yezinto eziningi ezine-nitrogen, njenge-creatine, i-choline, i-epinephrine, i-pinecone, i-carnitine, ne-myosin.

Isenzo se-Transaminopropyl

I-SAMe ibamba iqhaza ekuhlanganiseni ama-bioamine nge-transaminopropyl. I-Spermidine ne-spermidine ziyi-polyamine ebalulekile kuma-eukaryotes. Ngemva kwama-deshutter amabili, i-SAM ikhiqiza i-5 '-methiodophyl (MTA), bese idlulisela i-aminopropyl ku-putriamine noma i-spermidine ukuze ikhiqize i-spermidine ne-spermidine ehambisanayo.

Isenzo se-trans sulfure

I-SAMe iyisandulela esisebenzayo sezinhlanganisela eziqukethe isulfure njenge-cysteine ​​​​ne-glutathione (GSH). I-SAM ikhiqiza i-homocysteine ​​​​ngokuguqulwa kwesulfure, kulandelwa i-catabolic generation ye-cysteine, ebuye ivuselelwe ibe yi-glutathione (GS H).

Isicelo

Ukwelashwa kwe-viral hepatitis

Njenge-adenosylmethionine yangaphandle, i-S-adenosylmethionine ingangezelela i-adenosylmethionine engapheli ezinganeni ezinokulimala kwesibindi, inciphise ngempumelelo ukujikeleza kwe-enterohepatic ye-cholic acid, ivikele amaseli esibindi alimele, futhi ikhuthaze ukuhlehla kwe-jaundice. Ngaphezu kwalokho, i-S-adenosine methionine nayo iyasebenza ekwelapheni i-infantile liver syndrome.

Ukwelashwa kwesifo sesibindi esidakayo

Ucwaningo luye lwathola ukuthi i-s-adenosine ekwelapheni iziguli ezinesifo sokusha kwesibindi sotshwala ingathuthukisa kakhulu isifiso sabo sokudla, isicanucanu, ukuhlanza, ukukhathala, ukungezwani kwesisu, ukulunywa kwesikhumba nezinye izimpawu, ngasikhathi sinye ekunciphiseni i-serum bilirubin futhi kuthuthukise ukusebenza kwesibindi. inomphumela omuhle, futhi ukusetshenziswa okuphephile, akukho ukusabela okubi okusobala okutholakele kunqubo yokwelapha. Kodwa ukwelapha isifo sokusha kwesibindi kotshwala, ukungaphuzi kubaluleke kakhulu, futhi kuyindlela yakho yokwelapha eyisisekelo kakhulu.

Ukwelashwa kwe-Intrahepatic cholestasis yokukhulelwa

I-S-adenosyl-L-methionine powder ingathuthukisa kakhulu izinkomba ze-biochemical ze-cholestasis kanye nezimpawu ze-prurituria, ngakho-ke kubhekwa ukuthi i-S-adenosine ingenye yezidakamizwa eziphephile nezisebenzayo zokwelapha i-cholestasis ye-intrahepatic.