Igama Lomkhiqizo:I-Tianeptine Hemisulfate Monohydrate

Elinye Igama:tianeptinesulfate;

(Thiazepin-11-ylAmino)HeptanoicAcidSemisulfateMonohydrateTianeptineSemisulfateMonohydrate;

7-[(3-Chloro-6,11-dihydro-6-methyl-5,5-dioxidodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoicacidsulfatehydrate(2:1:2); I-Tianeptinehemisulfatemonohydrate(THM);

7- [(3-Chloro-6-methyl-5,5-dioxido-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoicacidsulfatehydrate(2:1:2); Tianeptinehemisulfatehydrate;Thiazepin-11-ylAmino)HeptanoicAcidSemisulfate;THM

Inombolo ye-CAS:1224690-84-9

Imininingwane: 98.0%

Umbala: I-crystal powder emhlophe enephunga elibonakalayo kanye nokunambitha

Isimo se-GMO:GMO Mahhala

Ukupakisha: ku-25kgs fiber drums

Isitoreji: Gcina isitsha singavulwa endaweni epholile, eyomile, gwema ukukhanya okuqinile

Impilo Yeshelufu: Izinyanga ezingama-24 kusukela ngosuku lokukhiqiza

I-Tianeptine Sulfate/Tianeptine hemisulfate monohydrate ingusawoti othuthukisiwe we-Tianeptine. Akuyona i-hygroscopic ngakho-ke ukuphatha i-powder kulula kakhulu. Njengoba ingangeni kalula futhi ikhishwe emzimbeni, usawoti we-sulfate uvumela ukukhululwa okulawulwa kakhulu kwe-Tianeptine esikhathini eside. Kunokuba udose kathathu ngemiphumela ephezulu esheshayo nemiphumela ewa ngokushesha, usawoti we-sulfate uvumela umthamo owodwa ukugcina amazinga e-plasma emzimbeni isikhathi eside kunosawoti wesodium. Lezi zici ezithuthukisiwe zenza i-Tianeptine Sulfate ibe isengezo senoveli.

I-Tianeptine Sulfate akuwona nje umphumela omuhle we-antidepressant kanye nokusabela okubi kwakungaphansi kakhulu kunezidakamizwa ze-tricyclic ezivamile, cishe akukho mphumela omubi ohlelweni lwenhliziyo nemithambo yegazi, igazi , isibindi nezinso azizange zilimale, futhi anginawo umphumela wokupholisa. I-Tianeptine ayisebenzi nje kuphela ekucindezelekeni kanye ne-neurosis ecindezelayo, ukudakwa okungapheli nokucindezeleka ngemva kotshwala nakho kuyasebenza. Ukusetshenziswa isikhathi eside kungavimbela ukuphinda

I-Tianeptine hemisulfate monohydrate, eyaziwa nangokuthi i-tianeptine sulfate, iyinhlanganisela eyingqayizivele eyatholwa okokuqala ngawo-1960 futhi isetshenziswe kabanzi kusukela ngaleso sikhathi.

I-Tianeptine iyi-antidepressant. Isilwane sinamaseli e-hippocampus pyramidal anda umsebenzi wokuzenzakalelayo, futhi ukusheshisa umsebenzi waso kwavinjelwa ngemva kokululama; ukwanda kwe-cortical kanye ne-hippocampalneurons ezindaweni ze-5-serotonin reuptake. I-Tianeptine ngaphandle kwemiphumela emibi elandelayo: ukulala nokuqwashisa;uhlelo lwenhliziyo nemithambo yegazi; uhlelo lwe-cholinergic (ngaphandle kwezimpawu ze-anticholinergic); ukunxanela izidakamizwa.

I-Tianeptine imithi kadokotela esetshenziselwa ukuthuthukisa ukucindezeleka kuzo zonke izigaba zobunzima. Imithi ye-tianeptine ngokuvamile ichazwa njenge-tricyclic antidepressant. Lokhu kuyinhlanganisela yamakhemikhali ebizwa kanjalo ngoba iqukethe izindandatho ezintathu zama-athomu.

Njengamanye ama-antidepressants e-tricyclic, i-tianeptine ivimba ukuphinda kuthathwe, noma ukumuncwa kabusha, kwe-serotonin. Lena i-neurotransmitter enesibopho somqondo womuntu wenhlalakahle. Ukuphinda kuthathwe ngenxa yalokho kukhulisa ukutholakala kwezinto ezinjalo ebuchosheni.

I-Tianeptine hemisulfate monohydrate, eyaziwa nangokuthi i-tianeptine sulfate, iyinhlanganisela eyingqayizivele eyatholwa okokuqala ngawo-1960 futhi ibisetshenziswa kabanzi kusukela ngaleso sikhathi. . Ngokuthuthukisa i-serotonin reuptake, i-tianeptine hemisulfate monohydrate isiza ukubuyisela ibhalansi yamakhemikhali ebuchosheni, okungenzeka kunciphise izimpawu zokudangala. Esinye sezici eziyingqayizivele ze-tianeptine hemisulfate monohydrate yikhono layo lokuthuthukisa i-neuroplasticity. I-Neuroplasticity ibhekisela emandleni obuchopho okushintsha nokuzivumelanisa nezimo ngokuhamba kwesikhathi. Ucwaningo lubonisa ukuthi i-tianeptine hemisulfate monohydrate ikhuthaza ukukhula kwama-neurons amasha futhi iqinise ukuxhumana okukhona ebuchosheni. Lesi sakhiwo sikwenza kube inketho ethokozisayo yokwelapha ukudangala, njengoba kunganikeza izinzuzo zesikhathi eside ngaphezu kokukhululeka kwezimpawu.

Umsebenzi:

I-Tianeptine Sulfate iyi-antidepressant. Isilwane sinalo: amangqamuzana e-hippocampus pyramidal anda umsebenzi ozenzakalelayo, futhi ukusheshisa umsebenzi wawo kwavinjelwa ngemva kokululama; ukwanda kwe-cortical kanye ne-hippocampal neurons kumasayithi we-5-serotonin reuptake. I-Tianeptine ngaphandle kwemiphumela emibi elandelayo: ukulala nokuqapha; uhlelo lwenhliziyo nemithambo yegazi; uhlelo lwe-cholinergic (ngaphandle kwezimpawu ze-anticholinergic); ukunxanela izidakamizwa.
I-Tianeptine Sulfate akuwona nje umphumela omuhle we-antidepressant kanye nokusabela okubi kwakungaphansi kakhulu kunezidakamizwa ze-tricyclic ezivamile, cishe akukho mphumela omubi ohlelweni lwenhliziyo nemithambo yegazi, igazi , isibindi nezinso azizange zilimale, futhi anginawo umphumela wokupholisa. I-Tianeptine ayisebenzi nje kuphela ekucindezelekeni kanye ne-neurosis ecindezelayo, ukudakwa okungapheli nokucindezeleka ngemva kotshwala nakho kuyasebenza. Ukusetshenziswa isikhathi eside kungavimbela ukuphinda.

Isicelo:

I-Tianeptine hemisulfate monohydrate iyi-serotonin reuptake enhancer (SSRE) ekhethiwe, okusho ukuthi ithuthukisa ukutholwa kabusha kwe-serotonin ebuchosheni, ngaleyo ndlela ikhulise i-synaptic plasticity futhi ithuthukise isimo sengqondo. Isebenza ngokushintsha amazinga e-serotonin ebuchosheni nokuthuthukisa i-neuroplasticity. Eminyakeni yamuva nje, i-tianeptine hemisulfate monohydrate iye yanda kakhulu ocwaningweni lwezokwelapha, ikakhulukazi ekwakhiweni kwezidakamizwa ezidambisa ukucindezeleka. Njengoba izifundo eziningi ziqinisekisa umphumela wayo wokwelapha, amathuba okusebenza kwawo ayavela kancane kancane