Sunan samfur:Agomelatine

Wani Suna: N-[2- (7-Methoxy-1-naphthyl) ethyl] acetamide; N-[2- (7methoxynaphthalen-1-yl) ethyl] acetamide

CAS No:138112-76-2

Musamman: 99.0%

Launi: Farar lafiya foda tare da halayyar wari da dandano

Matsayin GMO: GMO Kyauta

Shiryawa: a cikin 25kgs fiber ganguna

Adana: Ajiye akwati a buɗe a wuri mai sanyi, busasshiyar wuri, Nisantar haske mai ƙarfi

Rayuwar Shelf: watanni 24 daga ranar samarwa

Agomelatinesabon nau'in maganin damuwa ne. Tsarin aikinsa yana karyewa ta hanyar tsarin watsawa na monoamine na gargajiya.Agomelatine agonist melatoninergic ne kuma zaɓin antagonist na masu karɓar 5-HT2C, kuma an nuna yana aiki a cikin nau'ikan dabbobi da yawa na ciki. Agomelatine (S20098) ya nuna ƙimar pKi na 6.4 da 6.2 a ɗan ƙasa (porcine) da cloned, ɗan adam (h) 5-hydroxytryptamine (5-HT) 2C masu karɓa, bi da bi.

Agomelatine shine nau'in fari-fari ko fari lu'ulu'u ko fari mai ƙarfi. Sunan IUPAC na wannan sinadari shine N-[2- (7-methoxynaphthalen-1-yl) ethyl] acetamide. Wannan sinadari na Aromatics Compounds;Aromatics;Neurochemicals;APIS. Ya kamata a adana shi a zazzabi na -20 ° C.

 
A matsayin Matsakaicin Magunguna, Agomelatine ana amfani dashi a cikin maganin babban rashin damuwa, rashin tausayi. Ana amfani da Agomelatine a cikin maganin babban rashin damuwa, rashin tausayi. Abun magani don tsarin jijiya. Antidepressant, anxiolytic, daidaita rhythm na barci da kuma tsara nazarin halittu agogo. Agomelatine agonist melatoninergic ne kuma zaɓin antagonist na masu karɓar 5-ht2c. Agomelatine magani ne na antidepressant. An rarraba shi azaman disinhibitor na norepinephrine-dopamine (NDDI) saboda adawa da mai karɓar 5-HT2C. Agomelatine kuma mai ƙarfi ne mai ƙarfi a masu karɓar melatonin wanda ya sa shi ya zama farkon melatonergic antidepressant.

.Agomelatine yana da alaƙa da tsarin melatonin. Agomelatine mai karfin agonist ne a masu karɓar melatonin kuma mai adawa da masu karɓa na serotonin-2C (5-HT2C), an gwada shi a cikin samfurin dabba na ciki.

Agomelatine antidepressant ne da ake amfani dashi don magance damuwa.

Kwakwalwa yawanci tana da kyau wajen tabbatar muna da isassun sinadarai da muke buƙatar yin aiki yadda ya kamata. Amma damuwa na iya shafar adadin sinadarai na kwakwalwa.

Wadannan sinadarai sun hada da noradrenaline, dopamine da serotonin; baƙin ciki yana rage matakan waɗannan masu watsa kwakwalwa. Bacin rai kuma yana shafar wani sinadari mai suna melatonin. Ragewar melatonin yana da alaƙa da damuwa a yanayin barcinmu.

Agomelatine shine maganin ciwon kai na farko don haɓaka aikin melatonin kai tsaye. Yana yin haka ta hanyar yin kamar melatonin a wuraren da aka yi niyya inda melatonin ke aiki. (Waɗannan ana kiran su da masu karɓar melatonin). Ta hanyar haɓaka aikin melatonin, agomelatine shima yana haɓaka ayyukan noradrenaline da dopamine kai tsaye.

An fara ƙaddamar da Agomelatine a Turai a cikin 2009 kuma yanzu an amince da amfani da shi a cikin ƙasashe sama da 70. Ba kamar magungunan kashe-kashe na gargajiya ba, agomelatine yana aiki ta hanyar kai hari ga melatonin da masu karɓar serotonin a cikin kwakwalwa. Ta hanyar yin aiki azaman agonist a masu karɓar melatonin, agomelatine yana taimakawa daidaita yanayin bacci mai rugujewar sau da yawa hade da baƙin ciki. Wannan tsarin ba wai kawai yana taimakawa inganta ingancin barci ba amma yana taimakawa wajen dawo da rhythms na circadian na halitta. Bugu da ƙari, agomelatine yana aiki a matsayin mai adawa da wasu masu karɓa na serotonin (5-HT2C masu karɓa). Wannan aikin na musamman na dual a kaikaice yana haɓaka samuwar serotonin a cikin kwakwalwa, neurotransmitter da ke da alhakin daidaita yanayi. Ta hanyar daidaita matakan serotonin, agomelatine na iya yin aiki a matsayin ingantaccen maganin damuwa, kawar da bayyanar cututtuka kamar baƙin ciki, asarar sha'awa, jin laifi ko rashin amfani. Bugu da ƙari, agomelatine na iya ba da wasu fa'idodi. Bincike ya nuna yana iya taimakawa wajen inganta aikin fahimi Bincike yana nuna yiwuwar haɓaka ƙwaƙwalwar ajiya, hankali, da aikin zartarwa, yana mai da shi yanki mai ban sha'awa don bincike na gaba.

Aiki:

Agomelatine na iya taimakawa wajen daidaita agogon jikin ku (cikadian rhythm) tare da fa'idodi masu kyau akan yanayi da baccin bacci ana amfani da Agomelatine wajen maganin bacin rai ko don taimakawa hana baƙin ciki dawowa, kuma ana samun shi kaɗai tare da takardar sayan likita. Alamomin bakin ciki sun bambanta daga mutum ɗaya zuwa wani, amma yawanci sun haɗa da baƙin ciki na dindindin, asarar sha'awar ayyukan da aka fi so, jin rashin amfani, matsalolin barci, jin jinkirin, jin damuwa ko canje-canje na ci da nauyi. Canje-canje a cikin barcin ku na yau da kullun da tsarin sha'awa misalai ne na rikicewar agogon jikin ku wanda ke faruwa na yawan damuwa.