4-Butylresorcinol

inoa huahana: 4-Butylresorcinol pauka

Hōʻike: 98% min

Helu CAS: 18979-61-8

Nā huaʻōlelo Pelekane: N-BUTYLRESEOCINOL；4-N-BUTYLRESORSINOL；4-BUTYLRESORSINOL；4-phenylbutane-1,3-diol；2，4-DIHYDROXY-N-BUTYLbenZEN

Kumu molekala: C₁₀H₁₄O₂

Kaumaha molekula: 166.22

Ka helu hehee: 50~55 ℃

Ka helu hoʻolapalapa: 166 ℃/7mmHg (kukui.)

Ka helu: 0.1-5%

Pākē: 1kg, 25kg

HOIKE

He aha ka 4-Butylresorcinol

ʻO 4-n-butyl resorcinol ka inoa kemika, akā ʻo ka mea maʻamau, makemake nā mea a pau e maʻalahi i ke kākau ʻana i ka butyl resorcinol.ʻO ka mea mua e hoʻohui iā ia i ka huahana keʻokeʻo ʻo ia ka POLA Kepani, um~ ka mea e hilinaʻi nei i ka pill keʻokeʻo i ke ahi kūloko.

Hōʻike ʻia ʻo ia e ka hoʻoheheʻe maikaʻi ʻole i ka wai a hiki ke hoʻoheheʻe ʻia i ka ethanol.

Mechanism hana o 4-Butylresorcinol

• He kuleana koʻikoʻi ʻo Tyrosinase i ka hana ʻana o ka melanin no ka mea e kāohi ana i ka nui o ka hoʻopaʻa ʻana melanin.
• He hopena pale ka 4-n-butylresorcinol i ka hana ʻana o ka melanin ma ke kāohi pololei ʻana i ka hana o tyrosinase a me ka B16 ʻeleʻele-ʻeleʻele tumo cell e pale ana i ka synthesis o tyrosinase me ka ʻole o ka cytotoxicity.
• Ma kekahi mau haʻawina in vitro, ua hōʻike ʻia ʻo 4-n-butylresorcinol e kāohi i ka hana melanin, a me ka hana tyrosinase a me TRP-1.
• ʻO ka mea paʻa ikaika o tyrosinase a me peroxidase
• Mea hoʻomaʻemaʻe ʻili kūpono a me ka toner ʻili maʻamau
• He mea hoʻomaʻemaʻe maikaʻi no ka pigmentation o ka ʻili
• Hiki ke kū'ē i ka chloasma (ka ʻili hyperpigmented i ka lā)
• He hopena pale ikaika kona i ka pōʻino DNA i hoʻokomo ʻia e H2O2.
• Ua hōʻoia ʻia he hopena anti-glycation

Nā pono o 4-Butylresorcinol

No ke aha ʻoe e koho ai i ka 4-Butylresorcinol

ʻO ka mea mua, pono mākou e ʻike i ke kumu o ka resorcinol.

ʻO Lipofuscin kekahi o nā mea paʻakikī loa e hoʻopili i ka melanin.Ma keʻano laulā, hoʻohana ʻia ka hydroquinone i ka nani olakino.

ʻO ka Hydroquinone kahi mea hana keʻokeʻo maikaʻi loa.ʻO ka hana keʻokeʻo e pale i ka hana o tyrosinase a pale i ka hana ʻana o ka melanin, a he mea kupaianaha loa ka hopena.

Eia nō naʻe, ʻike like kona hopena ʻaoʻao, a ʻoi aku ka maikaʻi o nā pōmaikaʻi ma mua o nā pono o ka whitening.

• He oxidizable loa ia i ka lewa, a pono e hoʻohana ʻia i ka wā e hoʻohui ai i nā mea hoʻonaninani.
• hiki ke hana i ka ʻulaʻula o ka ʻili;
• Inā ʻoi aku ka nui o ka ʻike ma mua o 5%, e hoʻoulu ʻia ka sensitization, a aia kekahi mau hiʻohiʻona o ka leukoplakia.I kēia manawa, ʻōlelo ka US Food and Drug Administration i nā huahana hydroquinone me ka ʻoi aku ka nui ma mua o 4% he lāʻau lapaʻau a ʻaʻole ʻae ʻia e kūʻai ʻia.

Ua hoʻololi nā kemika a me nā lāʻau lapaʻau i ka hydroquinone lāʻau ikaika e kiʻi i ka 4-hydroxyphenyl-beta-D-glucopyranoside, ʻo ia ka mea a mākou e lohe pinepine ai e pili ana i ka "arbutin".ʻO ka ʻokoʻa ma waena o ka hydroquinone ʻo ka arbutin he huelo liʻiliʻi - glycoside ma mua o hydroquinone.He mea minamina ka hoʻemi nui ʻana o ka hopena keʻokeʻo.

ʻO nā makahiki i hala iho nei, ʻo nā mea kaulana loa o nā hōʻailona nui he mau derivatives o benzenediol.

Akā ʻilihune loa ka paʻa māmā o arbutin a maikaʻi wale nō i ka pō.

Ua lilo ka palekana o 4-n-butyl resorcinol i mea koʻikoʻi.Me ka ʻole o nā hopena ʻaoʻao o ka hydroquinone, ʻoi aku ka maikaʻi o ka hopena curative ma mua o nā derivatives resorcinol.

I loko o ka tyrosinase hana inhibition hoʻokolohua, kona ikepili ua oi aku ma mua o ka nui kaikunāne phenethyl resorcinol, i mea 100 ~ 6000 manawa o ka kuʻuna whitening agent e like me kojic acid arbutin!

A laila, i loko o ka hoʻokolohua hoʻokolohua B16V melanin, ua hōʻike pū kekahi i ka pono maʻamau o nā derivatives resorcinol - ka pale ʻana i ka hana melanin ma nā ʻano ʻaʻole i hana i ka cytotoxicity.

Eia kekahi, nui nā hoʻokolohua kanaka ma 4-n-butyl resorcinol.I loko o kekahi 32 mau maʻi me ka chloasma, 0.3% 4-n-butylresorcinol a me placebo i hoʻohana ʻia ma nā papalina ʻelua.ʻElua manawa i ka lā no 3 mau mahina, ʻo ka hopena he haʻahaʻa haʻahaʻa haʻahaʻa haʻahaʻa i ka hui 4-n-butylresorcinol ma mua o ka hui placebo.Aia kekahi poʻe e hana i nā hoʻokolohua hoʻoweliweli ʻana i ka pigmentation ma hope o ka sunburn artificial, hmm ~ maikaʻi loa ka hopena ~

Ka pale ʻana i ka tyrosinase kanaka e 4-butylresorcinol

Hōʻike ka 4-butylresorcinol, kojic acid, arbutin a me ka hydroquinone i ka hana L-DOPA oxidase o tyrosinase.Hoʻoholo ʻia e nā manaʻo like ʻole o nā inhibitors e ʻae i ka helu ʻana o nā waiwai IC50.ʻO kēia ʻikepili ka awelika o ʻekolu mau hoʻokolohua kūʻokoʻa.

Ka pale ʻana i ka hana ʻana o ka melanin i nā hiʻohiʻona ʻili MelanoDerm e 4-butylresorcinol

Hoʻohālikelike me ka 4-butylresorcinol, kojic acid, arbutin a me ka hydroquinone i ka hana melanin.Ua hōʻike ʻia ka hoʻoholo ʻana o ka melanin o nā hiʻohiʻona ʻili ma hope o 13 mau lā o ka mahiʻai ʻana ma ke alo o nā ʻano ʻokoʻa inhibitor.ʻO kēia ʻikepili ka awelika o ʻelima mau hoʻokolohua kūʻokoʻa.

ʻO ka hoʻomaʻamaʻa ʻana o ka makahiki e 4-butylresorcinol

E hoʻohālikelike me ka 4-butylresorcinol, kojic acid, arbutin a me hydroquinone.E mālama i nā kiko ʻelua i ka lā no 12 mau pule me kēlā me kēia inhibitor.E loiloi i ka pono ma hope o 4, 8 a me 12 pule.Hōʻike ka ʻikepili i ka mean o 14 mau kumuhana.*P <0.05: koʻikoʻi ka helu ʻana me nā kiko makahiki hoʻomalu i mālama ʻole ʻia.

Ka nui a me ka hoʻohana ʻana o 4-Butylresorcinol

ʻO ka dosage i ʻōlelo ʻia he 0.5%-5%.ʻOiai aia nā haʻawina ma Korea e loaʻa kahi hopena i ka 0.1% holika, a ua noiʻi ʻo India i ka 0.3% cream akā ʻo ka mākeke ʻo 0.5% -5%.ʻOi aku ka maʻamau, a ʻaʻole maopopo ka ʻōlelo Iapana, akā ua hoʻohana ʻia ʻo POLA.A he mea kupanaha nā hopena a me nā kūʻai.

E like me ka mea i ʻōlelo ʻia ma luna nei, hiki ke hoʻohana ʻia ka 4-Butylresorcinol i nā ʻaila, akā ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai.Loaʻa nā mea ʻē aʻe e like me nā lotions, nā ʻaila, a me nā gels.Loaʻa iā POLA a me Eucerin nā huahana 4-Butylresorcinol.