ʻO Beta-nicotinamide Mononucleotide (NMN), kahi huahana o ka hopena NAMPT a me kahi kī NAD + intermediate, hoʻomaikaʻi i ka intolerance glucose ma ka hoʻihoʻi ʻana i nā pae NAD + i nā ʻiole T2D i hoʻokomo ʻia e HFD.Hoʻonui pū ʻo NMN i ka naʻau o ka insulin hepatic a hoʻihoʻi i ka hōʻike gene e pili ana i ke koʻikoʻi oxidative, pane inflammatory, a me ka circadian rhythm, ma kahi o ka SIRT1 activation.Hoʻohana ʻia ʻo NMN no ke aʻo ʻana i nā kumu paʻa i loko o nā aptamers RNA a me nā kaʻina hana hoʻāla ribozyme e pili ana i nā ʻāpana RNA β-nicotinamide mononucleotide (Beta-NMN).
ʻO Nicotinamide mononucleotide ("NMN" a me "β-NMN") he nucleotide i loaʻa mai ka ribose a me ka nicotinamide.ʻO ka Niacinamide (nicotinamide,) kahi ʻano o ka huaora B3 (niacin.) Ma ke ʻano he biochemical precursor o NAD +, hiki ke hoʻohana i ka pale ʻana i ka pellagra.
Loaʻa kona ʻano i hoʻokaʻawale ʻole ʻia, ka niacin, i loko o nā kumu meaʻai like ʻole: Peanuts, Mushrooms (portobello, grilled), Avocados, Green Peas (hou), a me kekahi mau iʻa a me nā ʻiʻo holoholona.
Ma nā haʻawina [ma nā ʻiole], ua hōʻike ʻo NMN i ka hoʻohuli ʻana i ka maʻi ʻaʻai pili i ka makahiki ma o ka hoʻemi ʻana i ke kaumaha oxidative.
Inoa: Beta-ʻO Nicotinamide Mononucleotide
CAS ＃: 1094-61-7
inoa huahana: Beta-Nicotinamide Mononucleotide；NMN
Inoa ʻē aʻe:β-D-NMN;BETA-NMN;beta-D-NMN;NMN zwitterion;Nicotinamide Ribotide;Nicotinamide nucleotide;Nicotimide mononucleotide;Nicotinamide mononuclotide
CAS:1094-61-7
Huina mole: C11H15N2O8P
Kaumaha Molekala: 334.22
Maʻemaʻe: 98%
Ka Mahana Waihona: 2-8°C
Ke ʻano: ʻO ka pauka keʻokeʻo
Hoʻohana: anti-aging
Hana:
ʻO 1.Nicotinamide mononucleotide i loko o nā pūnaewele kanaka e pāʻani nui i ka hana ikehu, ua komo i loko o intracellular NAD (nicotinamide adenine dinucleotide, cell energy conversion important coenzyme) synthesis, hoʻohana ʻia i ka anti-aging, hāʻule ke koko koko a me nā huahana mālama olakino.
2. ʻO Nicotinamide Mononucleotide he huaora wai-soluble, ʻO ka huahana he keʻokeʻo crystalline pauka, ʻaʻohe ʻala a kokoke ʻole ʻole, ʻawaʻawa i ka ʻono, hiki ke hoʻoheheʻe ʻia i ka wai a i ʻole ethanol, dissolvable i ka glycerin.
ʻO 3.Nicotinamide Mononucleotide he maʻalahi ke komo i ka waha, a hiki ke hoʻolaha nui ʻia i loko o ke kino, ʻoi aku ka nui o nā metabolites a i ʻole prototype e kipaku koke mai ka mimi.ʻO Nicotinamide kahi ʻāpana o ka coenzyme I a me ka coenzyme II, hoʻokani i ke kuleana o ka hāʻawi ʻana i ka hydrogen i loko o ke kaulahao hanu oxidation biological, hiki ke hoʻoikaika i nā kaʻina hana oxidation biological a me ka metabolism o ka ʻiʻo, mālama i ka ʻiʻo maʻamau (ʻoi aku ka ʻili, ka digestive tract a me ka ʻōnaehana nerve) he kuleana koʻikoʻi ka pono. .
Eia kekahi, ʻo ka nicotinamide ka pale a me ka mālama ʻana i ka poloka naʻau, ka hana node sinus a me nā arrhythmias hoʻokolohua anti-wikiwiki, hiki i ka nicotinamide ke hoʻomaikaʻi nui i ka puʻuwai a me ka atrioventricular block i hoʻokumu ʻia e verapamil.
