Aha ngwaahịa:Archidonic acid

Nkọwapụta:10% ntụ ntụ, 40% mmanụ

CAS Mba.: 506-32-1

EINECS Mba.: 208-033-4

Usoro ihe omimi:C₂₀H₃₂O₂

Arọ molikula:304.46

Kedu ihe bụ Arachidonic acid?

Arachidonic acid (ARA) bụ nke Omega 6 polyunsaturated fatty acid nwere ogologo yinye.

Site naARAN'usoro, anyị nwere ike ịhụ na ọ nwere anọ carbon-carbon okpukpu abụọ nkekọ, a carbon-oxygen okpukpu abụọ, nke bụ nnukwu unsaturated ọdụdụ asịd.

ARA so na acid fatty dị mkpa?

Mba, Arachidonic Acid abụghị Fatty acids (EFAs) dị mkpa.

Naanị Alpha-linolenic acid (omega-3 fatty acid) na linoleic acid (omega-6 fatty acid) bụ EFA.

Otú ọ dị, a na-emepụta Arachidonic acid site na linoleic acid.Ozugbo ahụ anyị enweghị linoleic acid, ma ọ bụ enweghị ike ịtụgharị linoleic acid gaa na ARA, ahụ anyị ga-adị mkpụmkpụ nke ARA, yabụ AA na-ebubata n'ụzọ dị otú a.

Ihe enyemaka nri ARA

Nnyocha nyocha ahụike na nri nke mba 2005-2006

Ebee ka anyị ga-ahụ ARA na ndụ anyị

Ọ bụrụ na anyị na-elele ndepụta Efrata na Baby milk powder, Arachidonic Acid (ARA) nwere ike ịchọta dị ka otu n'ime ihe ndị dị mkpa maka mmepe ọgụgụ isi.

Ị ga-enwe ajụjụ, ARA ọ bụ naanị ihe dị mkpa maka ụmụ ọhụrụ?

Ee e, ọtụtụ ihe mgbakwunye ARA n'ahịa maka ahụike ụbụrụ na nri egwuregwu, na-enyere aka ịkwado oke akwara, ike, na nchekwa akwara n'oge ọzụzụ.

Arachidonic acid nwere ike ịrụ ọrụ maka ịrụ ahụ?

Ee.Ahụ na-adabere na ARA maka mbufụt, nzaghachi mgbochi nkịtị na nke dị mkpa iji rụkwaa anụ ahụ mebiri emebi.

Ọzụzụ ike ga-eme ka mmeghachi omume mkpali dị ukwuu, nke dị mkpa iji wuo akwara buru ibu.

Site na foto dị n'okpuru ebe a, anyị nwere ike ịhụ prostaglandins abụọ sitere na ARA bụ PGE2 na PGF2a.

Otu nnyocha e mere na eriri akwara skeletal na-egosi na PGE2 na-abawanye ndakpọ protein, ebe PGF2α na-akpali mmepụta protein.Nnyocha ndị ọzọ chọpụtakwara na PGF2a nwere ike ịbawanye ụba nke akwara skeletal.

Metabolism Arachidonic Acid zuru ezu

Prostaglandin Synthesis:

Ihe fọrọ nke nta ka ọ bụrụ mkpụrụ ndụ mammalian niile nwere ike ịmepụta prostaglandins na ogige ha metụtara (prostacyclins, thromboxanes na leukotrienes nke a makwaara dị ka eicosanoids).

Ọtụtụ eicosanoids sitere na ARA nwere ike ịkwalite mbufụt, mana ụfọdụ na-emekwa ihe iji dozie ya nke nhata mgbochi mkpali.

Prostaglandins Physiological mmetụta dị ka n'okpuru.

A na-emepụta prostaglandins site na enzymes ma na-emeghachi omume na ndị na-anabata protein jikọrọ G-protein, yana caMP na-agbazi ya n'ime cell.

Arachidonic acid na metabolism ya gụnyere Protaglandins (PG), Thromboxanes (TX) na Leukotrienes (LT)

Nchekwa ARA:

Nri ọhụrụ:

2008/968/EC: Mkpebi Commission nke 12 Disemba 2008 na-enye ikike itinye n'ahịa nke arachidonic acid bara ụba mmanụ sitere na Mortierella alpina dị ka ngwa nri akwụkwọ akụkọ n'okpuru Iwu (EC) Mba 258/97 nke European Parliament na Council (EC) mara ọkwa n'okpuru nọmba akwụkwọ C (2008) 8080)

GRAS

Mkpebi nke anabatara dị ka nchekwa (GRAS) nke mmanụ bara ụba nke arachidonic acid dị ka ihe oriri maka ngwa ngwa usoro ụmụaka.

Nri akụrụngwa ọhụrụ

Gọọmenti China kwadoro Arachidonic Acid dị ka ngwa nri akụrụngwa ọhụrụ.

Usoro ọgwụgwọ arachidonic acid

Maka ndị okenye: Ọkwa oriri ARA dị n'etiti 210-250 mg / ụbọchị na mba ndị mepere emepe.

Maka ịrụ ahụ: gburugburu 500-1,500 mg wee were nkeji 45 tupu mgbatị ahụ

Uru ARA:

Maka Baby

International Society for the Study of Fatty Acids and Lipids (ISSFAL) Onye isi ala - Prọfesọ Tom Brenna egosila ARA dị na mmiri ara ara mmadụ na nkezi nke 0.47% nke ngụkọta fatty acid.

Na ụmụ ọhụrụ na ụmụntakịrị oge, ikike nke nwa synthesize ARA dị ala, n'ihi ya, maka nwa na-na ọlaedo oge nke anụ ahụ mmepe, na-enye ụfọdụ ARA na nri ga-akawanye mma na mmepe nke physique ya.Enweghị ARA nwere ike inwe mmetụta dị njọ na mmepe nke anụ ahụ na akụkụ ahụ mmadụ, karịsịa mmepe nke ụbụrụ na usoro ụjọ.

Maka Okenye

Nrụpụta ahụ

Ọmụmụ ihe kpuru ìsì abụọ mere na 30 ahụ ike, ụmụ nwoke na-eto eto nwere ahụmahụ ọzụzụ ike nke afọ 2 ọ dịkarịa ala izu asatọ.

E kenyere onye ọ bụla so na ya ka ọ were iberibe abụọ dị nro nwere gram 1.5 nke ARA ma ọ bụ mmanụ ọka na-enweghị usoro.Ndị sonyere were softgel ahụ ihe dị ka nkeji 45 tupu ọzụzụ, ma ọ bụ mgbe ọ bụla dabara na ụbọchị na-abụghị ọzụzụ.

Nsonaazụ nyocha nke DXA na-egosi oke ahụ na-abawanye nke ukwuu na otu ARA naanị (+1.6 kilogram; 3%), Otu placebo fọrọ nke nta ka ọ nweghị mgbanwe ọ bụla.

Abụọ abụọ nke ọkpụkpụ akwara mụbara nke ukwuu ma e jiri ya tụnyere ntọala, mmụba dị ukwuu na otu AA (8% vs. 4% abawanye; p=0.08).

Maka oke abụba, enweghị mgbanwe dị ịrịba ama ma ọ bụ ọdịiche.

merie ịda mbà n'obi

Ndị nchọpụta chọpụtara na arachidonic acid nwere ike ibelata mgbaàmà ịda mbà n'obi ma gbanwee akara ngosi ụbụrụ na-adịghị mma.

E gosikwara na arachidonic acid nwere ike imeri ịda mbà n'obi nke ọma site n'ibelata ọbara.

Ịgwọ ọrịa ogbu na nkwonkwo

Maka ndị agadi

Ndị ọkà mmụta sayensị mere nnwale na oke, nkọwa dị n'okpuru.

N'ime oke, ọrụ nke enzyme nke na-agbanwe linoleic acid gaa na arachidonic acid na-ebelata site na ịka nká, na mgbakwunye nri na arachidonic acid na oke oke na-egosi na ọ na-akwalite cognition, na P300 amplitude And latency reviews, nke e megharịrị na 240 mg arachidonic. acid (site na 600 mg triglycerides) na ndị okenye ndị ọzọ nwere ahụike.

Ebe ọ bụ na Arachidonic acid na-emepụta obere oge n'oge ịka nká, mgbakwunye na arachidonic acid nwere ike inwe nkwalite ọgụgụ isi na ndị agadi.

Mmetụta

Ebe nguzozi nke omega-3 na omega-6 fatty acids bụ 1: 1 n'ime ahụ anyị.

Ọ bụrụ na anyị ewere ihe mgbakwunye Arachidonic Acid nke ukwuu, Omega 6 fatty acid nke ahụ anyị ga-adị elu karịa Omega-3, anyị ga-enwe nsogbu erughi Omega-3 (akpụkpọ ahụ kpọrọ nkụ, ntutu na-agbaji agbaji, urination ugboro ugboro, ehighị ụra nke ọma, mbọ mbọ aka, nsogbu itinye uche). na ọnọdụ mgbanwe).

Oke Omega-6 fatty acid nwere ike ibute ọrịa obi, ụkwara ume ọkụ, ọrịa autoimmune, abụba.

Iji jide n'aka na ị gaghị ezute nsogbu a, biko were Arachidonic acid dịka ndụmọdụ dọkịta gị siri dị.