Phosphatidylcholine nwere choline "isi" na glycerol phospholipids.Ọdụ nke glycerol phospholipids nwere ike ịbụ acid fatty dị iche iche.Ọtụtụ mgbe, otu ọdụ bụ fatty acid jupụtara, nke ọzọ bụ abụba na-adịghị mma.Mana ụfọdụ n'ime ha abụọ bụ abụba na-adịghị mma.Dịka ọmụmaatụ, phosphatidylcholine ngụgụ anụmanụ nwere oke dị elu nke dipalmitoyl phosphatidylcholine.
Aha ngwaahịa: Phosphatidylcholine PC
Aha ndị ọzọ: 1,2-diacyl-sn-glycero-3-phosphocholine, PC
Nkọwa ngwaahịa: Liquid / ma ọ bụ waxy siri ike: ihe dịka 60%
ntụ ntụ / granule: 10% - 98%,Nkọwapụta ewu ewu 20%, 50%, 98%
Nlereanya efu: dị
Ọdịdị: Ìhè edo edo ma ọ bụ ntụ ntụ, mmanụ ma ọ bụ waxy siri ike
Ule ule:HPLC
Ndụ shelf: afọ 2
Phosphatidylcholine nwere choline "isi" na glycerol phospholipids.Ọdụ nke glycerol phospholipids nwere ike ịbụ acid fatty dị iche iche.Ọtụtụ mgbe, otu ọdụ bụ fatty acid jupụtara, nke ọzọ bụ abụba na-adịghị mma.Mana ụfọdụ n'ime ha abụọ bụ abụba na-adịghị mma.Dịka ọmụmaatụ, phosphatidylcholine ngụgụ anụmanụ nwere oke dị elu nke dipalmitoyl phosphatidylcholine.
Phosphatidylcholine bụ isi akụrụngwa nke biofilms.Isi iyi dị nnọọ mfe na keukwu.Ị nwere ike nweta phosphatidylcholine site na ihe fọrọ nke nta ka ọ bụrụ nri ọ bụla na ndụ gị, ọ bụghị naanị nkochi ime akwa ma ọ bụ soybean.Ọ bụkwa lecithin na abụba anụmanụ.Ị nwere ike ịhụ phosphatidylcholine na anụ ahụ nke osisi na anụmanụ.N'ezie, mmepụta azụmahịa nke phosphatidylcholine bụ ngwaahịa dị ọcha nke nwere ọdịnaya dị elu na mmetụta kpọmkwem.
Phosphatidylcholine bụ ihe lipophilic hydrophilic;obere mmanya na-agbaze na C1 ruo C4, nke na-adịghị edozi na acetone na mmiri.
Ọ bụ ezie na a na-ejikarị PC eme ihe iji kwado ahụike ụbụrụ, ha nwekwara ike ịkwado ọrụ imeju na ịchịkwa ọkwa cholesterol.
Choline nwere ike ịgafe ihe mgbochi ụbụrụ ọbara n'ụzọ dị mfe site na sistemu na-akwalite mgbasa nke enweghị afọ ojuju, yana mgbanwe plasma ndị a nwere ike imepụta mgbanwe ndị yiri ya na ọkwa choline ụbụrụ.
N'ihi ntughari ezughị ezu nke usoro mgbanwe nke choline, ezughị oke nke mkpụrụ osisi choline, ọdịnaya choline na plasma na-abawanye, nke na-akwalite nhazi nke acetylcholine na phosphorylcholine na ntọhapụ nke acetylcholine.Ọ bụrụ na ọdịnaya nke ndị ọzọ na-ebute ụzọ nke phosphatidylcholine na-abawanye, usoro ntụgharị nke choline na phosphatidylcholine na-abawanye ụba nke peas.Ọkwa nke membranes synapti na ụbụrụ na-abawanye.Choline bụ metabolized ka ọ bụrụ betaine na imeju, nke bụ ụzọ bụ isi maka mmụgharị nke methionine na S-adenosylmethionine iji nye otu methyl.
Ọtụtụ n'ime metabolism nke imeju na-apụta na akpụkpọ ahụ cell nke nwere 33,000 square mita nke ahụ mmadụ.
Enwere ihe karịrị afọ 20 nke ule ụlọ ọgwụ gosiri na PC na-echebe imeju site na ọtụtụ n'ime mmetụta na-egbu egbu na-emebi membranes cell, dị ka ịṅụbiga mmanya ókè, ọgwụ ọjọọ, mmetọ, nje na mmetụta ndị ọzọ na-egbu egbu.
Ihe ọzọ na-ahụ maka PC bụ isi akụkụ nke akpụkpọ ahụ cell na ngụgụ, nke na-ebufe n'etiti akpụkpọ ahụ cell site na protein phosphatidylcholine transfer (PCTP).Ọ na-ekerekwa òkè na ngbanwe nrịbama cell nke mebere na akpụkpọ ahụ yana ịgbalite PCTP nke enzymes ndị ọzọ.
Enwere isi ihe mgbagwoju anya ebe a.Lecithin abụghị phosphatidylcholine.Phosphatidylcholine bụ akụkụ dị mkpa nke lecithin.
Uru nke phosphatidylcholine
Chebe imeju ka ọ ghara imerụ ahụ
Na-emeziwanye ọrụ ọgụgụ isi
Na-egbochi mmetụta nke ọgwụ ọjọọ
Mmetụta anwansi mgbochi ịka nká agbakwunyere na ịchọ mma
Ire ere lipid
Ịnagide ọrịa ulcerative colitis
Dị ka ọnụ ọgụgụ buru ibu nke nnwale anụmanụ, PC supplementation nwere ike ime ka acetylcholine (neurotransmitter na ụbụrụ), nke bụ ihe dị mkpa ihe iji melite ebe nchekwa.A na-aga n'ihu ọmụmụ ihe iji hụ mmetụta PC na nri ndị ọzọ na-emeziwanye ebe nchekwa na oke dementia.A maara na PC na ihe ndị ọzọ na-edozi ahụ nwere ụfọdụ mmetụta dị mma na mmetụta dị irè, ma ọ dị mkpa ịnwale ọzọ.N'ime omimi karị, na 2017, enwere ọmụmụ ihe metụtara ọkwa phosphatidylcholine na ọrịa Alzheimer.
Imeju bụ akụkụ dị mkpa na ahụ mmadụ, ụfọdụ ihe na-eme na ndụ kwa ụbọchị nwere ike ịkpata nnukwu ibu imeju, nke a na-enwekarị na imeju nwere abụba na ọrịa cirrhosis.
Nri buru ibu nwere ike inwe mmetụta na-adịghị mma na imeju.N’ezie, mmanya na-egbu egbu, ọgwụ ike, ihe ndị na-emetọ ihe, nje virus, na ihe ndị ọzọ na-akpata nsi, nwekwara ike imerụ imeju, na ịrụzi ya na-esi nnọọ ike.N'ime afọ 20 gara aga nke ule ụlọ ọgwụ, nchọpụta nke phosphatidylcholine ekereghị òkè dị mkpa na usoro ịzọpụta ndụ.Enwere ike ikwu na mmetụta ahụ adịghị mma, ma dị ka sildenafil e bu ụzọ mee ka ọ bụrụ ọgwụ ọgwụgwọ obi, a chọtara mmetụta ndị ọzọ na akụkụ nke atụmatụ ikpe.Site na nyocha nke ọma, anyị nwere ike ịchọpụta mmetụta nchebe nke PC na imeju dị ka permeability nke phosphatidylcholine na mmetụta nchebe ya na akpụkpọ ahụ cell.Ebe ọ bụ na enweghị ike ịrụzi ya, enwere ike ichebe ya tupu oge eruo, nke bụkwa isi ọrụ nke phosphatidylcholine.
Ọ bụ ezie na a na-eji phosphatidylcholine mee ihe dị ka mgbakwunye nri maka oriri ọnụ, ọ naghị egbochi ihe onwunwe ya dị iche iche.Dị ka ihe pụrụ iche nke anụ ahụ na nke ndu si dị, ọ nwere ike ịbanye n'ime akpụkpọ ahụ ngwa ngwa ma mee ka permeability nke ngwaahịa ndị ọzọ dịkwuo elu.Ya mere, ọtụtụ ndị na-emepụta ihe na-adị njikere iji phosphatidylcholine na ude nlekọta anụ ahụ dị n'èzí iji mepụta akpụkpọ anụ dị nro ma dị nro.Phosphatidylcholine gosikwara ezigbo nsonaazụ na ọgwụgwọ ihe otutu, yana mbelata 70% ihu igwe mgbe ụbọchị 28 gachara.
Phosphatidylcholine bụ molekul dị mkpa dị ndụ nke enwere ike ịhụ na sel ọ bụla nke ahụ mmadụ.Ụfọdụ ndị ọkà mmụta sayensị anwalela ụmụ oke ndị gbanwere site na mkpụrụ ndụ ihe nketa iji mepụta mmebi oxidative na mee ka ịka nká dịkwuo elu iji mụọ mmetụta phosphatidylcholine na ịka nká, mmụba nke uche na nkwalite ebe nchekwa na ndị ọrịa Alzheimer.N'ezie, ụfọdụ ndị ọkà mmụta sayensị kwenyere na egosipụtabeghị nke ọma mgbakwunye nke phosphatidylcholine iji gwọọ ọrịa Alzheimer.Ma usoro nke ịmepụta ụwa na-enweghị Alzheimer enweghị ike ịkwụsị.N'ezie, anyị enweghị ike na-achị na-ekwe omume na phosphatidylcholine nwere ọrụ, ma anyị mkpa ọzọ na ibu nnwale iji gosi na ya kpọmkwem ọrụ.
Mmetụta nke phosphatidylcholine
E gosipụtara nke ọma na akụkụ ahụike, ngwaahịa nwere PC nwere nri nwere ike were dị ka ntuziaka ahụ si dị;mgbe ejiri ya na ọgwụ, kwesịrị ịgbaso ntuziaka ndị dọkịta na ndị na-emepụta ọgwụ maka iji ọgwụ eme ihe.Iji zere ihe ize ndụ ndị a nke mmetụta dị n'akụkụ, malite na nke kachasị dị ala, a na-eji nwayọọ nwayọọ na-enweta dose kachasị.
PC ọnụ nwere ike ibute ọsụsọ gabiga ókè.Inwe ihe karịrị gram 30 kwa ụbọchị nwere ike ibute afọ ọsịsa, ọgbụgbọ, ma ọ bụ vomiting.
Ịbanye PC ozugbo n'ime etuto abụba nwere ike ibute nnukwu mbufụt ma ọ bụ fibrosis.O nwekwara ike bute mgbu, ọkụ, ọkụ, ọzịza ọbara, edema, na ọbara ọbara
Enwere ike iji mgbakwunye PC mee ihe n'ụdị capsule na mmiri mmiri na-enweghị ndenye ọgwụ.A na-ewere ha dị ka nchekwa ma ọ bụrụ na ejiri ya maka obere oge dị ka a gwara ya.Ndị ọkachamara ahụike ga-ejikwa injection nke PC.
