Product Name:Evodiamine

Rimwe Zita:Evodiamine, Isoevodiamine, (+)-Evodiamine, d-Evodiamine,Fructus Evodiae Extract

Nhamba yeCAS:518-17-2

Muedzo: 98%Maminitsi

Ruvara: Chiedza checrystalline poda

Kurongedza: mune 25kgs fiber zvigubhu

Kuchengeta: Chengetedza mudziyo usina kuvhurwa munzvimbo inotonhorera, yakaoma, Chengetedza kure nechiedza chakasimba

Sherufu Hupenyu: Mwedzi makumi maviri nemana kubva pazuva rekugadzirwa

Evodiamine yakasarudzika bioactive alkaloid uye chikuru bioactive chinhu mutsika Chinese mushonga. Inowanikwa mumabheri eEvodia evodia chirimwa, chinokura zvakanyanya muChina neKorea.Evodiamine is an unique bioactive alkaloid uye main bioactive ingredient mumutauro wechiChinese mushonga. Inowanikwa mumabheri eEvodia evodia chirimwa, chinokura zvakanyanya muChina neKorea. Chirimwa ichi chakapfuma mukusiyana kwemakemikari uye chagara chichishandiswa mumishonga yechinyakare yeChinese kurapa matambudziko akasiyana ehutano, anosanganisira kusagadzikana kwekugaya, kuzvimba, uye kurwadziwa. Evodiamine inoshanda nekunanga nzira dzakasiyana dzemamorekuru mumuviri. Iyo inozivikanwa kuti inokurudzira kushandiswa kwevanillin receptors, iyo inoita basa rakakosha mukunzwisisa marwadzo uye thermogenesis. Pamusoro pezvo, yakawanikwa ichidyidzana ne serotonin uye dopamine receptors, zvichiratidza kuti ine inogona kusimudzira mafungiro.

Biological chiitiko: Evodiamine is an alkaloid yakaparadzaniswa nemuchero weBentham, iyo ine zvakasiyana-siyana zvipenyu zvipenyu zvakadai sekurwisa-kuzvimba, anti obesity, uye anti-bundu. In vitro: Evodiamine yakaratidza cytotoxicity inopesana neakasiyana siyana kenza maseru mitsara nekuita apoptosis. Uye zvakare, ndeye yakasikwa yakawanda-yakatarisana anti-tumor molecule inoshandisa anti-bundu chiitiko kuburikidza neakasiyana mamorekuru masisitimu senge caspase inotsamira uye isina kutsamira nzira, sphingomyelin nzira, calcium / JNK kusaina, 31 PI3K / Akt / caspase, uye Fas. -L/. NF – κ B nzira yechiratidzo 32 [1]. In vivo: Evodiamine inhibits metabolism ye dapoxetine. Kuenzaniswa neboka rekutonga, t1 / 2, AUC (0- ∞), uye Tmax pharmacokinetic parameters ye dapoxetine muboka re evodiamine yakawedzerwa zvikuru ne 63.3%, 44.8%, uye 50.4%, maererano. Mukuwedzera, evodiamine yakaderedza zvakanyanya t1/2 pharmacokinetic parameters uye AUC (0- ∞) ye demethylated dapoxetine [2]. Evodiamine inhibits bundu kukura mu subcutaneous H22 xenograft modhi. Evodiamine attenuates VEGF induced angiogenesis in vivo.

In vitro: Evodiamine inoratidza cytotoxicity inopesana neakasiyana siyana kenza maseru mitsara nekuita apoptosis. Uye zvakare, ndeye yakasikwa yakawanda-yakananga anti-tumor molecule inoshandisa anti-bundu chiitiko kuburikidza neakasiyana mamorekuru nzira senge caspase inotsamira uye isina kutsamira nzira, sphingomyelin nzira, calcium / JNK kusaina, 31 PI3K / Akt / caspase, uye Fas. -L/. NF – κ B nzira yechiratidzo 32 [1].

In vivo: Evodiamine inhibits metabolism ye dapoxetine. Kuenzaniswa neboka rekutonga, t1 / 2, AUC (0- ∞), uye Tmax pharmacokinetic parameters ye dapoxetine muboka re evodiamine yakawedzerwa zvikuru ne 63.3%, 44.8%, uye 50.4%, maererano. Mukuwedzera, evodiamine yakaderedza zvakanyanya t1/2 pharmacokinetic parameters uye AUC (0- ∞) ye demethylated dapoxetine [2]. Evodiamine inhibits bundu kukura mu subcutaneous H22 xenograft modhi. Evodiamine attenuates VEGF induced angiogenesis in vivo.

BASA:

Anti-inflammatory, anti-tumor, uye hypoglycemic zviitiko zvine mamwe maitiro ekurapa pakurapa kwekutanga senile dementia uye sitiroko.Ine analgesic, inoderedza kumanikidzwa kweropa uye inokonzera kukwira kukuru kwemhedzisiro yekushisa kwemuviri. Chishandiso chekiriniki chechigadzirwa ichi kugadzira mishonga yemishonga ye diuretics uye dikita.

1. Evodia extract inoshandiswa kurapa zviratidzo zvekushungurudzika kwedumbu. Izvi zvinosanganisira kuda kurutsa, kurutsa, uye manyoka. Inonzi inonyanya kushanda mukurapa manyoka emangwanani.

2. Evodia inoshandiswa kukurudzira chido uye kurapa zviratidzo zvemudumbu zvine chokuita nekushaya chido mune zvekudya.

3. Evodia extract inewo anti-inflammatory, anti-tumor, anti-viral, astringent, uye diuretic properties.

4. Evodiamine ine analgesia, kuderedza ropa uye kupisa kwemuviri kukwira uye mamwe maitiro emishonga.

5. Evodiamine ine mudumbu, mira retching, oxyrygmia effect uye diuretic effect.

6.Evodiamine ine inhibitory yakasimba pa li; uye yakakosha insecticidal effect pa ascarissuum;

7.Evodiamine zvakare inogona kuderedza chibereko uye kuwedzera kudzvinyirira.

8.Besides, evodiamine inewo mhedzisiro yakanaka pachirwere cheAlzheimer uye sitiroko.

Application: