Paclitaxel is a monomer diterpenoid compound yakatorwa kubva Natural Plant Paclitaxel bark, imhando yakaoma yechipiri metabolites, parizvino inonzwisiswa chete mushonga unogona kukurudzira microtubule polymerization uye kugadzikana kwemamicrotubules akaunganidzwa.Isotope tracing yakaratidza izvozvopaclitaxelyakasungwa chete kune polymerized microtubules, kwete kune polymerized tubulin mbiri.Sero kuonanapaclitaxelmushure mekuunganidzwa kwehuwandu hukuru hwema microtubules mumasero, izvo zvinokanganisa microtubule kuunganidzwa kweakasiyana masero mabasa, kunyanya kupatsanurwa kwesero kumira mu mitosis, ichivharira yakajairika kupatsanurwa kwesero.
Zita reChigadzirwa: Paclitaxel99.0%
Fomu: White crystalline powder
Mutengo: 99%
Test Method: HPLC
Nhamba yeCAS: 33069-62-4
Molecular Formula:C47H51NO14
Boiling Point:957.115 °C pa760 mmHg
Molecular uremu: 853.91
GMO Mamiriro:GMO Yemahara
Kurongedza: mune 25kgs fiber zvigubhu
Kuchengeta: Chengetedza mudziyo usina kuvhurwa munzvimbo inotonhorera, yakaoma, Chengetedza kure nechiedza chakasimba
Sherufu Hupenyu: Mwedzi makumi maviri nemana kubva pazuva rekugadzirwa
Basa:
1.Paclitaxel inonyanya kushandiswa kugomarara reovarian nezamu, kenza yemapapu, colorectal cancer, melanoma, musoro negotsi kenza, lymphoma, uye zvakare ine imwe mhedzisiro pamamota europi.
2.Iyo kugadzikana zvinodhaka zvinogona kukurudzira microtubule polymerization uye microtubule polymerization.
3.Kuchave kwakaunganidzwa nhamba huru ye microtubules mumasero mushure mekusangana ne paclitaxel, kuunganidza kwe microtubules kunopindira nekushanda kwesero, kunyanya, kumisa kupatsanurwa kwesero mu mitosis, kuvharidzira kupatsanurwa kwesero.
Application:
Inoshandiswa mukudzidza kwechimiro uye basa remamicrotubles mu tubulin.Paclitaxel yave kushandiswa kurapa varwere vane mapapu, ovarian, kenza yemazamu, kenza yemusoro nemutsipa, uye mafomu epamberi eKaposi's sarcoma.Paclitaxel inonzi mitotic inhibitor inoshandiswa mukenza chemotherapy.
| Mamwe ruzivo nezve TRB | ||
| Regulation certification | ||
| USFDA,CEP,KOSHER HALAL GMP ISO Zvitupa | ||
| Kuvimbika Hunhu | ||
| Anoda kusvika makore makumi maviri, kunze kwenyika makumi mana nematunhu, mabheji anopfuura zviuru mazana maviri anogadzirwa neTRB haana chero matambudziko emhando, nzira yekucheneswa, kusachena uye kuchena kutonga zvinosangana neUSP, EP uye CP. | ||
| Comprehensive Quality System | ||
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| ▲ Hunhu Hwekusimbisa Sisitimu | √ |
| ▲ Kudzora zvinyorwa | √ | |
| ▲ Validation System | √ | |
| ▲ Kudzidzisa System | √ | |
| ▲ Internal Audit Protocol | √ | |
| ▲ Suppler Audit System | √ | |
| ▲ Equipment Facilities System | √ | |
| ▲ Material Control System | √ | |
| ▲ Kugadzira Kudzora System | √ | |
| ▲ Packaging Labeling System | √ | |
| ▲ Laboratory Control System | √ | |
| ▲ Verification Validation System | √ | |
| ▲ Regulatory Affairs System | √ | |
| Dzora Manyuko Akazara uye Maitiro | ||
| Yakanyatso kudzora zvese mbishi zvinhu, zvekushandisa uye kurongedza zvinhu. Preferred mbishi zvinhu uye zvishongedzo uye kurongedza zvinhu mupi neUS nhamba yeDMF. Vanoverengeka vatengesi vezvinhu zvakasvibiswa sevimbiso yekugovera. | ||
| Strong Cooperative Institutions kutsigira | ||
| Institute of botany/Institution of microbiology/Academy of Science and Technology/University | ||
