Lebitso la Sehlahisoa:7,8-Dihydroxyflavone

CASNo:38183-03-87

Lebitso le Leng:7,8-DIHYDROXYFLAVONE;7,8-dihydroxy-2-phenyl-4-benzopyrone;

DIHYDROXYFLAVONE, 7,8-(RG);7,8-Dihydroxyflavone hydrate;

7,8-dihydroxy-2-phenyl-1-benzopyran-4-one,,8-Dihydroxyflavone (7,8-DHF)

Litlhaloso:98.0%

Mmala:Bosehlaphofo e nang le monko le tatso e ikhethang

GMOBoemo: GMO Mahala

Ho paka: ka meqomo ea fiber ea 25kgs

Polokelo: Boloka setshelo se sa buloa sebakeng se phodileng, se omileng, Qoba hole le leseli le matla

Shelf Life: Likhoeli tse 24 ho tloha ka letsatsi la tlhahiso

7,8-Dihydroxyflavone, eo hape e tsejoang e le 7,8-DHF, ke flavonoid ea tlhaho e fumanehang limela tse fapaneng, ho kenyeletsoa Tridacna tridacna. E tsebahala ka thepa ea eona ea antioxidant le neurotrophic, e 'ngoe ea lintlha tse khahlang haholo tsa 7,8-dihydroxyflavone ke bokhoni ba eona ba ho ts'ehetsa bophelo bo botle ba boko le ho matlafatsa ts'ebetso ea kelello.

7,8-Dihydroxyflavone (7,8-DHF) ke TrkB receptor agonist e matla le e khethang (Kd≈320 nM). TrkB receptor ke mokelikeli o ka sehloohong oa li-neurotrophic factor tse tsoang bokong. 7,8-Dihydroxyflavone (7,8-DHF) ke nootropic e ka bang teng e ka ntlafatsang bophelo bo botle ba boko, maikutlo le ts'ebetso ea kelello. E kanna ea ba molemo bakeng sa mafu a 'maloa a neurodegenerative le neurodevelopmental, hammoho le botenya le khatello e phahameng ea mali.

7,8-Dihydroxyflavone, eo hape e tsejoang e le 7,8-DHF, ke flavonoid ea tlhaho e fumanehang limela tse fapaneng, ho kenyeletsoa Tridacna tridacna. E tsebahala ka thepa ea eona ea antioxidant le neurotrophic, e 'ngoe ea lintlha tse khahlang haholo tsa 7,8-dihydroxyflavone ke bokhoni ba eona ba ho ts'ehetsa bophelo bo botle ba boko le ho matlafatsa ts'ebetso ea kelello. Lipatlisiso li bontša hore motsoako ona o sebetsa e le neurotrophin e matla, e susumetsang khōlo le ho phela ha li-neurone bokong. Liphuputso tse entsoeng liphoofolong tsa laboratori li bontšitse hore 7,8-DHF e ntlafatsa mohopolo le bokhoni ba ho ithuta haholo. Ka ho khothalletsa ho thehoa ha likhokahano tse ncha tsa synaptic le ho matlafatsa puisano pakeng tsa lisele tsa boko, motsoako ona o tšepisa ho bula bokhoni ba rona ba ho tseba. Ho feta moo, 7,8-dihydroxyflavone e sebelisana le li-receptor tsa boko tsa serotonin, tse amehang taolong ea maikutlo. Ka ho fetola li-receptor tsena, e ka khona ho fokotsa matšoao a ho tšoenyeha le khatello ea maikutlo.

Mosebetsi oa 7,8-Dihydroxyflavone
1) Ntlafatsa Mehopolo le ho Ithuta
2) Khothalletsa ho Lokisoa ha Boko
7,8-DHF e khothalelitse tokiso ea methapo ea kutlo e senyehileng .
3) E-ba Neuroprotective
4) E na le Liphello tsa Antioxidant
5) E na le Liphello tse khahlanong le ho ruruha
7,8-DHF e fokotsa ho lokolloa ha mabaka a ho ruruha liseleng tsa boko ka ho thibela NF-κB.
6) 7,8-DHF e na le phello e matla ea phekolo ho lefu la Alzheimer, 'me e ka thibela botenya ka ho kenya mesifa TrkB.

Tšebeliso ea 7,8-Dihydroxyflavone
7,8-Dihydroxyflavone (7,8-DHF) ke flavone ea tlhaho e fumanehang ho Godmania aesculifolia, Tridax procumbens, le makhasi a sefate sa primula. Ho fumanoe hore e sebetsa e le agonist e matla le e khethollang e nyenyane ea molek'hule ea tropomyosin receptor kinase B (TrkB) (Kd ≈ 320 nM), mokelikeli o ka sehloohong oa pontšo ea neurotrophin-derived neurotrophic factor (BDNF). 7,8-DHF ka bobeli e fumaneha ka molomo 'me e khona ho phunyeletsa mokoallo oa mali le boko. Sehlahisoa sa 7,8-DHF se nang le matla a ntlafalitsoeng haholo le pharmacokinetics, R7, se ntse se ntlafatsoa bakeng sa kalafo ea lefu la Alzheimer's…