J-147 Phofo

J-147 Powder e Featured Image
  • J-147 Phofo

Tlhaloso e Khutšoanyane:

J147 ke J-147 ke motsoako o matla ka mokhoa o ikhethang, o sebetsang ka molomo le o pharaletseng oa neuroprotective o na le bokhoni ba ho ntlafatsa mohopolo ho liphoofolo tse tloaelehileng hammoho le ho thibela ho haelloa ke mohopolo ho lefu la Alzheimer's (AD) litoeba tse sa tloaelehang. Mesebetsi ea neurotrophic le e matlafatsang mohopolo ea J-147 e amahanngoa le ho eketseha ha boko bo tsoang ho neurotrophic factor (BDNF) le polelo ea liprotheine tse arabelang tsa BDNF, ho ntlafatsa LTP, ho boloka protheine ea synaptic, ho fokotseha ha li-amyloid plaques.


  • FOB Theko:US $0.5 - 2000 / KG
  • Bongata ba Odara:1KG
  • Matla a Phepelo:10000 KG/Kgwedi
  • Boema-kepe:SHANGHAI/BEIJING
  • Melao ea Tefo:L/C,D/A,D/P,T/T
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    Lebitso la Sehlahisoa:J-147 Phofo

    Lebitso le Leng:2,2,2-Trifluoroacetic acid 1-(2,4-DiMethylphenyl) -2-[(3-Methoxyphenyl)Methylene]hydrazide],J-147, J147

    Nomoro ea CAS:1146963-51-0

    Tekanyetso: 99.0% Min

    'Mala: Phofo e tšoeu

    Ho paka: 25kgs Meropa

     

    J-147ke neuroprotectant e matla e sebetsang ka ho khetheha ka molomo e nkiloeng haholo-holo ho curcumin, motsoako o sebetsang ho turmeric. Ho fapana le curcumin, e tšela mokoallo oa mali-boko ka katleho haholo.

    J-147 ke sesebelisoa se matla ka ho ikhethang, se sebetsang ka molomo, se sireletsang methapo ea kutlo bakeng sa ntlafatso ea kelello.
    J-147 e khona ho feta habonolo mokoallo oa boko ba mali (BBB). J-147 e ka thibela monoamine oxidase B (MAO B) le sepalangoang sa dopamine se nang le litekanyetso tsa EC50 tsa 1.88 μM le 0.649 μM, ka ho latellana. J-147 e na le monyetla oa ho phekola lefu la Alzheimer's

    J-147 ke neuroprotectant e matla ka ho khetheha e sebetsang ka molomo e nkiloeng haholo-holo ho curcumin, motsoako o sebetsang oa turmeric. Ho fapana le curcumin, e tšela mokoallo oa mali-boko ka katleho haholo. Har'a bona, J-147 e sebetsa ka ho tlama ho ATP synthase. Tlhahiso e feteletseng ea ATP e amahanngoa le mokhoa oa ho tsofala. Ntle le ho eketseha ha maemo a li-neurotransmitters NGF le BDNF, J-147 e ka laola sena. Ntle le moo, J-147 e thibela monoamine oxidase B le dopamine transporter. E khothalletsa ho hola ha boko ka ho eketsa maemo a methapo ea kutlo (NGF) le neurotrophic factor (BDNF) e tsoang bokong. Habohlokoa le ho feta, J-147 e ka khothaletsa kholo ea lisele tse ncha tsa methapo, ea ntlafatsa bokhoni ba boko ba ho ithuta le mohopolo, le ho ntlafatsa ts'ebetso ea kelello.

    Mosebetsi:

    J-147 e khona ho feta habonolo mokoallo oa boko ba mali (BBB).
    J-147 e ka thibela monoamine oxidase B (MAO B) le sepalangoang sa dopamine se nang le litekanyetso tsa EC50 tsa 1.88 μM le 0.649 μM, ka ho latellana.
    J-147 e na le monyetla oa ho phekola lefu la Alzheimer's (AD).
    J-147 e na le monyetla oa ho phekola lefu la Alzheimer's (AD).

    Kopo:

    J-147 ke motsoako oa maiketsetso oo mokhoa oa oona o ka sehloohong oa ts'ebetso o kenyelletsang ntlafatso ea mitochondrial, kahoo e ntlafatsa tlhahiso ea matla boemong ba lisele. J-147 e etselitsoe ho ntlafatsa bokhoni ba boko ba ho itokisa le ho itšireletsa tšenyo e amanang le lilemo ka ho ntlafatsa tšebetso ea mitochondrial. Ho feta moo, J-147 e bonts'a thepa ea bohlokoa e khahlanong le ho ruruha le antioxidant, e ntlafatsang le ho feta litlamorao tse ka bang teng tsa neuroprotective. J-147 e ka khothaletsa kholo ea lisele tse ncha tsa methapo, ea ntlafatsa bokhoni ba boko ba ho ithuta le mohopolo, le ho ntlafatsa ts'ebetso ea kelello.

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