Tataiso e Akaretsang ea Sehlahisoa:Kojic Acid Dipalmitate98% (HPLC) bakeng sa Bosoeu ba Letlalo le Khahlanong le Botsofali
1. Selelekela hoKojic Acid Dipalmitate
Asiti ea KojicDipalmitate (KAD, CAS79725-98-7) ke motsoako oa liposoluble oa kojic acid, o tumme ka ho tsitsa ha eona, ho sebetsa hantle, le polokeho ho litlolo tsa litlolo. Joaloka moloko o latelang oa tyrosinase inhibitor, e fokotsa ka katleho motsoako oa melanin, e sebetsana le hyperpigmentation, 'me e khothalletsa esita le letlalo la letlalo. Ka bohloeki ba 98% bo netefalitsoeng ke HPLC, motsoako ona o loketse lihlahisoa tsa boemo bo holimo tsa letlalo tse shebileng matheba a lefifi, melasma le ho fifala ho amanang le lilemo.
Lisebelisoa tsa Bohlokoa:
- Ho Khantša Letlalo: Ho thibela tlhahiso ea melanin ka ho thibela tšebetso ea tyrosinase, ho feta tloaelo ea kojic acid.
- Anti-Botsofali: E fokotsa mela e metle le ho matlafatsa letlalo le boreleli ka thepa ea antioxidant.
- Mefuta e mengata ea mesebetsi: E lumellana le li-serum, litlolo, litlolo tse sireletsang letsatsi, le lihlahisoa tsa anti-acne.
2. Thepa ea Lik'hemik'hale le 'Mele
Foromo ea Limolek'hule: C₃₈H₆₆O₆
Boima ba 'mele: 618.93 g / mol
Ponahalo: Phofo ea kristale e tšoeu ho isa bosoeu
Sebaka se qhibilihang: 92–95°C
Solubility: Ho qhibiliha ha oli (ho lumellana le li-ester, oli ea liminerale le lino tse tahang).
Melemo ea botsitso:
- pH Range: E tsitsitse ho pH 4–9, e loketse mefuta e fapaneng ea metsoako.
- Thermal/Light Resistance: Ha ho na oxidation kapa discoloration tlas'a mocheso kapa mahlaseli a UV, ho fapana le kojic acid.
- Metal Ion Resistance: E qoba chelation, ho netefatsa botsitso ba nako e telele ea mebala.
3. Mokhoa oa ho Etsa
KAD e sebetsa ka mekhoa e 'meli:
- Thirosinase Inhibition: E thibela sebaka sa enzyme, e thibelang tlhahiso ea melanin. Liphuputso li bontša hore 80% e sebetsa hantle ho feta kojic acid.
- Phatlalatso e Laoloang: Li-esterases letlalong li etsa hore KAD e be hydrolyze ho kojic acid e sebetsang, e etsa bonnete ba hore ho na le depigmentation e tsitsitseng.
Melemo ea Melemo:
- E fokotsa matheba a lilemo, post-inflammatory hyperpigmentation (PIH), le melasma .
- E ntlafatsa ts'ebetso ea setlolo se sireletsang letsatsi ka ho fokotsa melanogenesis e bakoang ke UV.
4. Melemo FetaAsiti ea Kojic
| Paramethara | Asiti ea Kojic | Kojic Acid Dipalmitate |
|---|---|---|
| Botsitso | Oxidizes habonolo, e fetoha mosehla | Mocheso / khanya e tsitsitseng, ha ho na mmala |
| Solubility | Metsi a qhibilihang | Ho qhibiliha ha oli, ho monya ha letlalo ho molemo |
| Kotsi ea ho teneha | E itekanetseng (pH-sensitive) | Tlase (bonolo bakeng sa letlalo le bonolo) |
| Boikemisetso ba ho theha | E lekanyelitsoe ho acidic pH | E lumellana le pH 4-9 |
5. Tataiso ea ho Etsa
Recommended Dosage: 1–5% (3–5% bakeng sa bosoeu bo matla) .
Kenyelletso ea Mohato ka Mohato:
- Tokisetso ea Phase ea Oli: Qhala KAD ka isopropyl myristate/palmitate ka 80 ° C bakeng sa metsotso ea 5.
- Emulsification: Kopanya karolo ea oli le karolo ea metsi ho 70 ° C, homogenize metsotso e 10.
- Phetoho ea pH: Boloka pH 4-7 bakeng sa botsitso bo nepahetseng.
Mohlala oa Foromo (Whitening Serum):
| Motsoako | Peresente |
|---|---|
| Kojic Acid Dipalmitate | 3.0% |
| "Niacinamide" | 5.0% |
| Asiti ea Hyaluronic | 2.0% |
| Vithamine E | 1.0% |
| Li-preservative | qs |
6. Polokeho le Boikamahanyo
- Non-Carcinogenic: Mekhatlo e laolang (EU, FDA, China CFDA) e fana ka tumello ea KAD bakeng sa tšebeliso ea litlolo. Liphuputso li tiisa hore ha ho kotsi ea kankere.
- Setifikeiti: ISO 9001, REACH, le likhetho tsa Halal/Kosher lia fumaneha.
- Eco-Friendly: E tsoa ho lisebelisoa tse tala tse senang bokhopo tse seng GMO.
7. Packaging le Logistics
Boholo bo fumanehang: 1 kg, 5 kg, 25 kg (e ka khonahala)
Polokelo: Sebaka se phodileng, se omileng (<25°C), se sireleditswe kganya .
Global Shipping: DHL / FedEx bakeng sa disampole (matsatsi a 3-7), thepa ea leoatleng bakeng sa litaelo tse ngata (matsatsi a 7-20) .
8. Ke Hobane'ng ha U Khetha KAD ea Rōna 98% (HPLC)?
- Tiisetso ea Bohloeki: 98% e netefalitsoe ke HPLC, ka COA le MSDS e fanoeng.
- Tšehetso ea R&D: Therisano ea mahala ea tekheniki le liteko tsa sampole.
- Tšebeliso e tsitsitseng: Ho sebelisana le barekisi ba netefalitsoeng ke ECOCERT.
9. Lipotso-potso
P: Na KAD e bolokehile bakeng sa mebala e lefifi ea letlalo?
A: Ho joalo. Boemo ba eona ba ho teneha bo tlase bo etsa hore e loketse mefuta ea letlalo ea Fitzpatrick IV-VI.
P: Na KAD e ka nkela hydroquinone sebaka?
A: Ho joalo. KAD e fana ka katleho e tšoanang ntle le cytotoxicity.
Mantsoe a bohlokoa: Kojic Acid Dipalmitate, Skin Whitening Agent, Tyrosinase Inhibitor, Phokotso ea Melanin, Tataiso ea ho Etsa Litlolo, Phekolo ea Hyperpigmentation, Sejo se tsitsitseng sa Whitening.
Tlhaloso: Tseba saense ka mor'a Kojic Acid Dipalmitate 98% (HPLC) - e tsitsitseng, e sa hloekiseng letlalo. Ithute malebela a eona a ho theha, mokhoa, le lintlha tsa polokeho bakeng sa mebaraka ea EU/US.
