Tataiso e Pharalletseng ea Cosmetic Grade Hyaluronic Acid (HA): Thepa, Melemo, le Lisebelisoa
1. Selelekela
Hyaluronic Acid (HA), eo hape e tsejoang e le hyaluronan kapa sodium hyaluronate, ke motsoako oa phetoho litlolong tsa sejoale-joale. Joalo ka glycosaminoglycan ea tlhaho, HA e bapala karolo ea bohlokoa ho pholileng ha letlalo, ho thibela botsofali le ho lokisa lisele. Ka bokhoni ba eona bo ke keng ba lekanngoa ba ho boloka mongobo le biocompatibility, HA e se e le lejoe la motheo la litlolo tsa skincare tse lebisitsoeng ho bareki ba lefats'e, haholo-holo Europe le Amerika Leboea. Tataiso ena e shebana le mahlale, lits'ebetso, le melemo ea khoebo ea HA, ea boleng bo holimo, ea cosmetic-grade, e ntlafalitsoeng hore e bonahale ho Google le ho ikamahanya le mekhoa ea ho batla Bophirimela.
2. Tlhaloso ea Sehlahisoa
2.1 Sebopeho sa Lik'hemik'hale le Mehloli
HA ke polysaccharide e melang e entsoeng ka likarolo tse pheta-phetoang tsa disaccharide:D-glucuronic acidleN-acetylglucosamine, e kopantsoeng ke β-1,3 le β-1,4 glycosidic bonds. HA Commercial HA e na le sebopeho sa eona sa letsoai la sodium (sodium hyaluronate), e matlafatsang ho qhibiliha le botsitso. HA ea rona e hlahisoa ka ho belisoa ha likokoana-hloko tlas'a maemo a thata a GMP le ISO 9001, ho netefatsa hore na o tsoa hokae, o hloekile haholo (> 95%), le ho lumellana ha batch-to-batch.
2.2 Mefuta e fapaneng ea Boima ba Limolek'hule
Boima ba limolek'hule bo hlophisitsoeng (MW) bo thusa ho sebelisa litlolo tse fapaneng:
- High MW (1,000–1,800 kDa): E etsa filimi e sireletsang holim'a letlalo, e koala mongobo le ho fokotsa tahlehelo ea metsi a transepidermal (TEWL) .
- MW e Bohareng (200–400 kDa): E leka-lekanya hydration le ho kenella bakeng sa li-serum le litlolo.
- MW e tlase (5–10 kDa): E kenella ka har'a likarolo tse tebileng tsa epidermal ho susumetsa motsoako oa collagen le ho lokisa.
- Oligo-HA (≤5 kDa): E ntlafatsa ho tsosolosoa ha lisele le mosebetsi oa antioxidant.
3. Melemo ea Bohlokoa ea HA ka Litlolo
3.1 Hydration e phahameng
HA e ka kopanya boima ba eona ka makhetlo a 1,000 metsing, e leng se etsang hore e be tekanyetso ea khauta bakeng sa ho kolobisa letlalo le omeletseng le le se nang metsi. Sebopeho sa eona sa hygroscopic se tiisa hore ho na le metsi a lihora tse 24, ho ntlafatsa letlalo le boreleli.
3.2 Khahlanong le Botsofali le Phokotso ea Masobana
Ka ho tlatsa dermal HA e lahlehileng ka botsofali, e khutlisetsa molumo oa letlalo, e boreleli mela e metle, 'me e matlafatsa ho tiea. Liphuputso tsa bongaka li bontša hore 0.1% HA serum e fokotsa botebo ba masoebi ka 20% nakong ea libeke tse 4.
3.3 Matlafatso ea Litšitiso
HA e matlafatsa mokoallo oa lipid oa letlalo, e sireletsa khahlanong le khatello ea maikutlo (mohlala, UV, tšilafalo) le ho fokotsa kutlo.
3.4 Ho feto-fetoha ha maemo ho Liqapi
E tsamaellana le litlolo, li-serum, li-gel le limaske, HA e hokahana le metsoako e kang vithamine B5, peptides le ceramides ho matlafatsa ts'ebetso. Mohlala, ho kopanya HA le niacinamide ho matlafatsa litlamorao tse khanyang ka 30%.
4. Litaelo tsa Tšebeliso
4.1 Litekanyo tse khothalelitsoeng
- Litlolo / Li-gel: 0.1-0.5% HA phofo kapa 10-50% HA tharollo bakeng sa viscosity e nepahetseng le ho ata.
- Lihlahisoa tsa Tlhokomelo ea Mahlo: Sebelisa 1.3-1.5 milione ea Dalton HA ho fokotsa boikhohomoso le li-circles tse lefifi.
- Tlhokomelo ea Letsatsi: ≥0.1% HA e ntlafatsa ts'ireletso ea UV le ho lelefatsa litlamorao tsa mongobo.
4.2 Sepheo sa Matšoenyeho a Letlalo
- Letlalo le omileng: Botoro ea MW HA + e phahameng ea shea.
- Letlalo la Botsofali: Low MW HA + retinol.
- Sensitive Skin: Oligo-HA + oat extract.
5. Tšireletseho le Litifikeiti
- E sa Halefeng: E Feta Setifikeiti sa Setifikeiti sa ECOCERT le tlhahlobo ea dermatologist.
- Tumellano ea GMP/ISO: E entsoe ka meaho e hlahlobiloeng bakeng sa boleng le ho latelloa.
- Taolo ea Taolo: E Kopana le EU Cosmetic Regulation (EC) No 1223/2009 le tataiso ea FDA bakeng sa tšebeliso ea lihlooho.
6.
- Mantsoe a bohlokoa: Kopanya mantsoe a kang "HA eo e seng phoofolo," "cosmetic-grade sodium hyaluronate," le "serum serum e thibelang botsofali" lihloohong le litlhalosong tsa meta .
7. Qetello
Our cosmetic-grade HA e ka pele-pele ho boqapi ba skincare, e fana ka bohloeki bo ke keng ba lekanngoa, polokeho le katleho. E tšehetsoa ke theknoloji ea ho belisoa ha likokoana-hloko le litifikeiti tsa lefats'e, e matlafatsa lihlahisoa ho theha lihlahisoa tse sebetsang hantle tse lumellanang le bareki ba hlokomelang tikoloho. Bakeng sa liforomo tse tsamaellanang le litlhoko tsa hau, ikopanye le sehlopha sa rona sa tekheniki kapa khoasolla datha e felletseng.
