S-adenosyl-L-methionine disulfate tosylate

Lebitso la Sehlahisoa:S-adenosyl-L-methionine disulfate tosylate

Lebitso le Leng:Ademetionine disulfate tosylate; AdeMethionine Disulfate Tosylate; SAM-TAdemetionine disulfate tosylate; Ademetionine Disulfate Tosylate (SAMME)

Nomoro ea CAS:97540-22-2

Tekanyetso: 98% Min

Mmala: Phofo e ntle e tšoeu

Boemo ba GMO:GMO Mahala

Ho paka: ka meqomo ea fiber ea 25kgs

Polokelo: Boloka setshelo se sa buloa sebakeng se phodileng, se omileng, Qoba hole le leseli le matla

Shelf Life: Likhoeli tse 24 ho tloha ka letsatsi la tlhahiso

SAMe e fana ka sehlopha sa methyl ka mefuta ea biosynthesis ea liprotheine, li-neurotransmitters, nucleic le nucleic acid. Sena se etsahala liketsong tse ngata tsa enzymatic transmethylation.

Adenosylmethionine (SAMe) ke motsoako o hlahang ka tlhaho o fumanehang hoo e batlang e le liseleng le mokelikeli o mong le o mong 'meleng. E ameha lits'ebetsong tse ngata tsa bohlokoa. SAMe e na le karolo tsamaisong ea 'mele ea ho itšireletsa mafung, e boloka lera la lisele, 'me e thusa ho hlahisa le ho senya lik'hemik'hale tsa boko, tse kang serotonin, melatonin le dopamine.

Ho nka SAMe ka molomo ho bonahala ho sebetsa hammoho le ibuprofen le lithethefatsi tse ling tse tšoanang ho fokotsa matšoao a osteoarthritis. Empa batho ba bangata ba hloka ho noa SAMe nako e ka etsang khoeli pele ba ikutloa ba le betere.

Batho ka kakaretso ba sebelisa SAMe ho phekola khatello ea maikutlo, osteoarthritis le lefu la sebete. Leha ho le joalo, SAMe e ka boela ea sebelisana le meriana e thibelang ho imeloa kelellong.

E ka 'na ea ntša lintho tse kotsi' meleng. Tsena li kenyelletsa litšepe tse boima. E ka boela ea thibela tšenyo ea sebete ho tloha chefo ea acetaminophen le ho thusa ho thibela mafura a mafura a sebete sa hau. E ka boela ea thusa ho fokotsa mokhathala le ho fokotsa kotsi ea ho ba le lefatla kapele.

Liseleng tsa eukaryotic, SAM e sebetsa e le molaoli oa mekhoa e sa tšoaneng e kenyeletsang DNA, tRNA, le rRNA methylation; karabelo ea 'mele ea ho itšireletsa mafung; amino acid metabolism; transsulfuration; le ho feta. Limeleng, SAM e bohlokoa ho biosynthesis ea ethylene, hormone ea bohlokoa ea semela le molek'hule ea lipontšo.

T-Adenosylmethionine (SAMe) ke motsoako o hlahang ka tlhaho o fumanehang hoo e batlang e le liseleng le mokelikeli o mong le o mong 'meleng. E ameha lits'ebetsong tse ngata tsa bohlokoa. SAMe e na le karolo tsamaisong ea 'mele ea ho itšireletsa mafung, e boloka lera la lisele, 'me e thusa ho hlahisa le ho senya lik'hemik'hale tsa boko, tse kang serotonin, melatonin le dopamine.

Mosebetsi

Transmethylation

SAMe ke mofani oa methyl ea bohlokoa ka ho fetisisa 'meleng, mme bonyane ho fumanoe hore ho na le liphetoho tse 35 tse fapaneng tsa methyl transferase tse hlokang SA M joalo ka mofani oa methyl. SAM e sebelisetsoa biosynthesis ea lintho tse ngata tsa naetrojene, tse kang creatine, choline, epinephrine, pinecone, carnitine le myosin.

Ts'ebetso ea transaminopropyl

SAMe e kenya letsoho ho hlahisoeng ha bioamine ka transaminopropyl. Spermidine le spermidine ke polyamine ea bohlokoa ho eukaryotes. Ka mor'a li-deshutter tse peli, SAM e hlahisa 5 '-methiodophyl (MTA), ebe e fetisetsa aminopropyl ho puttriamine kapa spermidine ho hlahisa spermidine le spermidine tse tšoanang.

Ketso ea sebabole sa Trans

SAMe ke selelekela se sebetsang sa metsoako e nang le sebabole e kang cysteine ​​le glutathione (GSH). SAM e hlahisa homocysteine ​​​​ka phetoho ea sebabole, e lateloa ke catabolic generation ea cysteine, e ntan'o tsosolosoa ho glutathione (GS H).

Kopo

Phekolo ea kokoana-hloko ea lefu la sebete

Joaloka adenosylmethionine e sa tloaelehang, S-adenosylmethionine e ka tlatsetsa endogenous adenosylmethionine ho bana ba nang le tšenyo ea sebete, ka katleho e fokotsa phallo ea enterohepatic ea cholic acid, e sireletsa lisele tse senyehileng tsa sebete, le ho khothalletsa ho fokotseha ha lefu la jaundice. Ho phaella moo, S-adenosine methionine e boetse e sebetsa ho phekola lefu la sebete sa masea.

Kalafo ea lefu la sebete sa joala

Liphuputso li fumanoe hore s-adenosine ha ho phekoloa bakuli ba lefu la sebete la tahi e ka ntlafatsa haholo takatso ea bona ea lijo, ho nyekeloa ke pelo, ho hlatsa, mokhathala, ho hlohlona ha mpa, ho hlohlona ha letlalo le matšoao a mang, ka nako e ts'oanang ho fokotsa serum bilirubin le ho ntlafatsa ts'ebetso ea sebete. e na le phello e ntle, 'me tšebeliso e bolokehileng, ha ho litlamorao tse hlakileng tse fumanoeng ts'ebetsong ea kalafo. Empa phekolo ea lefu la sebete la tahi, ho se noe joala ke ea bohlokoa haholo, hape ke mokhoa oa eona oa motheo oa phekolo.

Kalafo ea Intrahepatic cholestasis ea bokhachane

S-adenosyl-L-methionine phofo e ka ntlafatsa haholo lipontšo tsa biochemical tsa cholestasis le matšoao a prurituria, kahoo ho nkoa hore S-adenosine ke e 'ngoe ea lithethefatsi tse sireletsehileng le tse sebetsang bakeng sa phekolo ea intrahepatic cholestasis.