Igama lemveliso:I-Lithium Orotate99%

Izithethantonye: i-orotic acid lithium ityuwa monohydrate;

lithium,2,4-dioxo-1H-pyrimidine-6-carboxylate;4-Pyrimidinecarboxylic acid;1,2,3,6-tetrahydro-2,6-dioxo-, ityuwa ye-lithium (1: 1);I-C5H3LiN2O4Ifomula yeMolekyuli:C₅H₃LiN₂O₄

Ubunzima beMolekyuli: 162.03

Inombolo yeCAS:5266-20-6

Imbonakalo/umbala:Mhlophe ukuya kumhlophe-umgubo wekristale

Iinzuzo:Imvakalelo enempilo kunye nengqondo

I-Lithium orotate yikhompawundi ye-lithium eyaziwayo phakathi kwabasebenzisi bongezelelweyo.Sele kukho iityuwa ezininzi ze-lithium kwimarike, ezifana ne-lithium aspartate, i-lithium carbonate, kunye ne-lithium chloride, njl. Ewe, i-lithium orotate yiyona kuphela i-lithium enesondlo kwizongezo zokutya, kwaye abasebenzisi bayakwazi ukuthenga ii-capsules ze-lithium orotate kwi-amazon, eWalmart. , Ivenkile yeVithamini ngokukhululekileyo ngaphandle komyalelo kagqirha.

Ngoko ke, kutheni i-lithium orotate iyingqayizivele?
Ngaphambi kokuba sifike kwinqanaba, makhe sihlolisise iimpawu ezisisiseko ze-lithium orotate zomzimba kunye neekhemikhali.

Izinto eziluhlaza ze-lithum orotate (inombolo ye-CAS 5266-20-6), ikwimo yomgubo omhlophe ukuya kumhlophe

ILithium Citrate isoloko ikwimo yeLithium Citrate Syrup kwisisombululo.I-5 mL nganye ye-Lithium Citrate Syrup equkethe i-8 mEq ye-lithium ion (Li +), ilingana nomlinganiselo we-lithium kwi-300 mg ye-lithium carbonate.Isiphuzo esithambileyo i-7Up ye-Coca-Cola yayisetyenziselwa i-Lithium Citrate kwifomula yayo, kodwa i-Coca yayisusa kwi-7Up ngo-1948. Nanamhla, i-Lithium citrate ayisetyenziswanga kwezinye izinto zokutya okanye iziselo.

I-Lithium orotate VS Lithium aspartate

NjengeLithium orotate, i-lithium aspartate ikwathathwa njengesithako esongezelelweyo sokutya, kodwa azikho iinkampani ezininzi ezongezelelweyo eziyisebenzisayo.

Ngoba?

I-Lithium orotate kunye ne-lithium aspartate ziphantse zibe nobunzima obufanayo be-molecular (162.03 kunye ne-139.04 ngokulandelanayo).Baneenzuzo ezifanayo zokusebenza, kwaye iidosi zabo ziphantse zifane (130mg & 125mg ngokulandelanayo).Iingcali ezininzi zezondlo, ezifana noDkt Jonathan Wright, zincoma i-lithium orotate kunye ne-lithium aspartate ngokulinganayo.

Ke, kutheni i-lithium orotate ithandwa kakhulu emva koko i-lithium aspartate?

Izizathu zisenokuba ngenxa yeziphumo ebezingalindelekanga ezinetyhefu ezibangelwa yi-lithium aspartate.

I-aspartate ithathwa njenge-excitotoxin.I-Excitotoxins zizinto ezibophelela kwi-nerve cell receptor kwaye zibangele umonakalo ngokuvuselela kakhulu.Ukugqithisa i-Lithium aspartate kunokubangela ukusabela kwe-excitotoxic kubantu ababuthathaka, kwaye iziphumo ziquka iintloko, imiba ye-CNS, iingxaki ze-vascular, njl. iaspartate.Kuya kuba yinto efanelekileyo ukuba bathathe i-lithium orotate endaweni yoko.

I-Lithium orotate VS I-Lithium carbonate

I-lithium carbonate kunye ne-lithium citrate ziziyobisi ngelixa i-lithium orotate iyongeza ukutya.

I-Lithium carbonate yindlela echazwe ngokuqhelekileyo ye-lithium evunywe yi-FDA ukunyanga i-bipolar disorder, kunye ne-lithium citrate ibe yinto yesibini eqhelekileyo ye-lithium echazwe ngamagqirha.

Ngenxa yokungafumaneki kakuhle kwe-bioavailability, iidosi eziphezulu ze-lithium carbonate kunye ne-citrate ye-lithium ziqhele ukufunwa (2,400 mg-3,600 mg ngosuku) ukufezekisa izibonelelo ezifunwayo.Ngokwahlukileyo, i-130 mg lithium orotate iyakwazi ukubonelela malunga ne-5 mg elemental lithium nge-capsule nganye.I-5 mg ye-lithium orotate yongezelela ilungile ngokwaneleyo ukuba ibe nemiphumo emihle kwimoya kunye nempilo yengqondo.

Amanqanaba aphezulu e-lithium carbonate kufuneka athathwe ukuze afumane umphumo owanelisayo wonyango.Ngelishwa, ezi dosi zonyango ziphakamisa amanqanaba egazi kangangokuba asondele kumanqanaba anetyhefu.Ngenxa yoko, izigulane ezithatha i-lithium carbonate okanye i-lithium citrate kufuneka zibekwe iliso elibukhali kumanqanaba egazi anetyhefu.I-Serum lithium kunye ne-serum creatinine amanqanaba ezigulane eziphathwe nge-lithium kufuneka zibekwe esweni rhoqo kwiinyanga ezi-3-6.

Nangona kunjalo, i-lithium orotate, indibaniselwano ye-lithium kunye ne-orotic aicd, ayinayo iingxaki ezinjalo.i-lithium orotate i-bioavailable ngaphezu kweefom ze-carbonate kunye ne-citrate, kwaye iyakwazi ukuhambisa i-lithium yendalo ngqo kwiiseli zengqondo ezifuna kakhulu.Kwi-adition, i-lithium orotate ayinayo imiphumo ebalulekileyo kwaye akukho mfuneko yokuba i-lithium orotate ibekwe esweni kwidosi.

IiNdlela zokuSebenza zeI-Lithium Orotate

I-Lithium orotate idlala indima enkulu ekusebenzeni kwengqondo okunempilo, ukuxhasa umoya ophilileyo, impilo yeemvakalelo, ukuziphatha kunye nenkumbulo.Isebenza njani i-lithium orotate ngokuchanekileyo?

Ngokutsho kweWikipedia, indlela ethile ye-biochemical yesenzo se-lithium ekuzinziseni isimo sengqondo ayaziwa.I-Lithium yenza iziphumo zayo kumanqanaba amaninzi iqala ngotshintsho lweklinikhi kwisimo sengqondo ngokuchasana ne-mania kunye nokudakumba kunye nokunciphisa ukuzibulala.Ubungqina beziphumo ze-lithium kwi-cognition evela kwi-neuropsychological kunye nezifundo ze-magnetic resonance imaging imaging zikhomba ngokubanzi ukuya kwi-cognitive compromise;nangona kunjalo, ubungqina boku buye baxutywa.Izifundo zokucinga ngesakhiwo zibonelele ngobungqina bokhuseleko lwe-neuroprotection kunye nokwanda kwemithamo engwevu, ngakumbi kwi-amygdala, i-hippocampus kunye nemimandla ye-cortical yangaphambili kwizigulana eziphathwe nge-lithium.Utshintsho kwi-neurotransmission enempembelelo yeklinikhi inokuchazwa ngokunyuka kwe-inhibitory kunye nokunciphisa ukuhanjiswa kwe-neurotransmission kwizigulane ezine-lithium.Kwinqanaba le-intracellular, i-lithium inefuthe kwiinkqubo zesithunywa sesibini, ezenza i-neurotransmission kwaye iququzelele ukusebenza kweselula ngokukhuthaza ukukhuselwa kwe-anti-oxidant, ukunciphisa i-apoptosis, kunye nokwandisa iiprotheni ze-neuroprotective.

Nangona kunjalo, iindlela ezintathu eziphambili ziye zachongwa kule minyaka ingamashumi amabini idlulileyo kwiziphumo ezibanzi ze-neuroprotective ze-lithium kwingqondo kunye nenkqubo ye-nervous:

• ukunyuswa kweprotheyini enkulu ye-neuroprotective Bcl-2,
• ukulawulwa kweBDNF,

I-Brain-Derived Neurotrophic Factor (BDNF) ngokuqhelekileyo ibizwa ngokuba "Ummangaliso wokukhula kwengqondo" kuba kwandisa i-neurogenesis.I-Neurogenesis kukukhula kwee-neuron ezintsha, ukunika ingqondo yakho "uphuculo lwe-biochemical" olufuneka kakhulu ngelixa uphuma kwi-opioids.I-BDNF ikwabonelela nge-antidepressant enamandla kunye

anti-ixhala iziphumo.

• kunye nokuthintelwa kwe-NMDA receptor-mediated excitotoxicity

IiNzuzo zeLithium Orotate

I-Lithium orotate sisongezelelo sendalo sokutya esinokusetyenziswa kwiidosi ezincinci ukulawula uxinzelelo kunye nokuxhasa isimo sengqondo esihle ngakumbi.

I-Lithium Orotate yesimo sengqondo esisempilweni

I-lithium orotate yafunyanwa kuqala ukunyanga ukudakumba kwe-manic (ngoku eyaziwa ngokuba yi-bipolar disorder), ibisetyenziswa ixesha elide ukuzinzisa imo kunye nokunyanga iziphazamiso ezininzi zemo.

I-Lithium orotate iphucula ukuhlanganiswa kunye nokukhululwa kwehomoni eyonwabileyo ye-serotonin.Kwangaxeshanye, ityuwa ye-orotate ikwanciphisa ihomoni yoxinzelelo norepinephrine.

I-Lithium orotate iyakwazi ukunceda abantu ngokunciphisa uvakalelo lobuchopho kwi-norepinephrine receptors.Ithintela ukuveliswa kwale neurotransmitter eyaziwayo echaphazela umoya wethu.Ngenxa yezi ziphumo zokuzinzisa isimo sengqondo, iidosi ezisezantsi ziyaphononongwa kubantu abanexhala.I-Lithium ibonakalisiwe kwizifundo zokuzola isimilo somntu esinxulunyaniswa nexhala, ukuphazamiseka kwengqondo, kunye nokuphazamiseka kokungakhathali (ADHD).

I-Lithium Orotate yengqondo ephilileyo

I-Lithium orotate ithandwa kwezinye iifomyula ze-nootropic.I-Nootropics iyakwazi ukuphucula imemori kunye neminye imisebenzi yokuqonda.

Izifundo ezininzi zesayensi zibonise ukuba i-lithium orotate supplement inokunyusa i-grey kwingqondo yomntu, ithintele ukukhutshwa kwe-beta-amyloid kwaye ikhulise i-NAA.Enye indlela yokukhusela ebizwa ngokuba yi-lithium orotate iyancipha ukusebenza ngokugqithisileyo kweprotheyini yeseli yobuchopho ebizwa ngokuba yi-tau protein ekwanegalelo ekuwohlokeni kwe-neuronal njengoko kwenza ukwakheka kwee-neurofibrillary tangles.Abantu abaneentlobo ezahlukeneyo zokulimala kwengqondo kunye neengxaki banokulindela ukuphucuka kwimisebenzi yabo yengqondo.

I-Lithium orotate ngenxa yotywala

I-lithium orotate inokuba luncedo kwiminqweno yotywala.Olunye uphando lwafumanisa ukuba xa izigulana ezinqwenela utywala zanikwa i-lithium orotate, ziye zakwazi ukugcina ukuzola kwazo ixesha elide kunye nemiphumo emibi encinci.Izazinzulu ziye zaphinda ezi ziphumo kolunye uphononongo, ngokunjalo.

ILithium Orotate Dosage

Ngokubanzi, zininzi izongezelelo ze-lithium kunye namachiza kwintengiso yokutya nakwintengiso yamayeza.Yi-lithium Li + edlala indima ephambili yokusebenza.Umlinganiselo jikelele we-elemental lithium yi-5mg.

I-molecular weight of Li yi-6.941, ibalwa kwi-4% ye-Lithium orotate (162.03).Ukubonelela nge-5mg elemental lithium, i-dosage ye-lithium orotate yi-125mg.Ngoko uya kufumanisa ukuba i-lithium orotate kwii-lithium ezininzi zongezelelo i-colse ukuya kwi-125mg.Enye ifomula inokuba yi-120mg, enye inokuba yi-130mg, kwaye akuyi kubakho mahluko kakhulu.

Lithium orotate ukhuseleko

Uninzi lweempawu ezongezelelweyo ezifuna ukuzama i-lithium orotate kwiifomyula zabo zokongeza zimalunga nalo mbuzo.

Ngokubanzi, i-Lithium orotate sisithako sendalo sokutya, akukho myalelo we-FDA ofunekayo.Abasebenzisi bayakwazi ukuthenga izongezo eziqulethe i-lithium orotate kwi-amazon, i-GNC, i-Iherb, i-Vitamin Shoppe, i-Swan, kunye namanye amaqonga ngokukhululekileyo.

Nangona kunjalo, ukudosa kubaluleke kakhulu.I-Lithium isebenza kakhulu kwidosi ephantsi kwi-5mg.Ungagqithi kwidosi ecetyiswayo yengcali yakho yezempilo.Qhagamshelana nogqirha wakho ngolwazi olungakumbi.