Ngokutsho kweWikipedia, igama le-IUPAC lepiperlongumine yi-1-[(2E)-3-(3,4,5-Trimethoxyphenyl)prop-2-enoyl]-5,6-dihydropyridin-2(1H)-enye, kunye nezinye. iiwebhusayithi zikhetha ukusebenzisa i-5,6-dihydro-1-[(2E) -1-oxo-3- (3,4,5-trimethoxyphenyl) -2-propenyl] -2 (1H) -pyridinone.
Igama elipheleleyo lekhemikhali ye-piperlongumine lide kwaye akukho bantu banokukhumbula, ngoko abaphandi basebenzisa i-piplatine okanye i-piperlongumine kuninzi lwamaxwebhu esayensi.Kwaye i-20069-09-4 yinombolo yayo ebhalisiweyo yeCAS.
Igama lemveliso:I-Piperlongumine powder
Elinye igama: Piplatin,I-Piperlongumineisicatshulwa, i-Piplatine, 5,6-Dihydro-1-[(2E) -1-oxo-3- (3,4,5-trimethoxyphenyl) -2-propen-1-yl] -2(1H) -pyridinone,PPLGM , i-pippali powder, i-Piper Longum extract
CAS Ninombolo: 20069-09-4
Umthombo wezityalo:Piper Longum Linn
Isivavanyi: 98% min
Isampulu yasimahla :Iyafumaneka
Imbonakalo: Umgubo omhlophe wekristale
Iinzuzo:Anti-umhlaza, anti-ukuguga, senolytic
Ubomi beShelf: iminyaka emi-2
I-Piperlongumineifumaneka kakhulu kwiPiper longum, isityalo esiphuma eMzantsi Asia.I-Indiya kunye ne-China ngamazwe amabini aphambili athengisa i-Piper longum powders kunye nezongezelelo kwi-Amazon nakwezinye iiwebhusayithi ze-e-commerce.
IPiper longum yaziwa ngokuba yipepile ende okanye ipippali eIndiya.I-Piper longum iqulethe i-alkaloids, i-amides, i-Lignans, i-Esters, i-oyile eguquguqukayo, njl.
Isiqhamo sePiper longum sisetyenziswe kwinkqubo ye-Ayurvedic yeyeza kunye neMichiza yesiNtu yaseTshayina ixesha elide kakhulu.
Iinkcazo zePiperlongumine
Akukho bulk piperlongumine powder kwimarike okwangoku.Uninzi lwababoneleli ziinkampani ze-reagent, kwaye iimveliso zabo zezokusetyenziswa kophando kuphela.Ukongezelela, ubuninzi babo buhlala kuphela kwi-10mg ukuya kwi-500mg kwibhotile encinci kakhulu.
Kukho izicatshulwa zomlinganiselo weplanti yepiper longum, eneenkcukacha ezidumileyo ezifana ne-4:1, 10:1, 20:1, njl.
Iimveliso zezityalo zaseIndiya eziqulethe i-piperlongumine ubukhulu becala isicatshulwa.Zingaphi iipiperlongumines ezikuyo?Akukho mntu owaziyo.Kuphela i-piperlongumine esemgangathweni evela kwi-piper longumine inokulinganiswa.
iinkcukacha yi-98% min.
Ukuba unayo nayiphi na imibuzo, nceda ungalibazisi ukuqhagamshelana nathi ngeenkcukacha ezithe vetshe.
Ukunyibilika kwePiperlongumine
IPiperlongumine ayinyibiliki emanzini.Ke ukuba ufuna ukusebenzisa ngokupheleleyo izongezo ze-piperlongumine, kufuneka wenze i-piperlongumine kwiifom ze-capsules endaweni yepilisi ye-piperlongumine okanye i-powders.
I-Piperlongumine iyanyibilika kwizinyibilikisi ze-organic ezifana ne-ethanol, i-DMSO, kunye ne-dimethylformamide (DMF).
Indlela yokuSebenza yePiperlongumine
Iinzuzo zePiperlongumine
Njengeyeza lemveli elisetyenziswa e-China nase-Indiya, isityalo se-piper longum sichazwa njenge-tonic yokuphefumla, kwaye ilungile kwi-digestion enempilo kunye ne-immune system.
Kwi-piperlongumine ngokwayo, i-anti-cancer kunye ne-anti-aging zezona zinto zixhalabisayo.
I-Piperlongumine yokuchasana nokuguga (senolytic)
I-Piperlongumine yi-arhente yenoveli yenoveli.Ukuba ufuna ukwazi ukuba i-piperlongumine isebenza njani ukulwa nokuguga, kufuneka wazi iiseli ze-senescent kuqala.
Iiseli zeSenescent zidlala indima ebalulekileyo kwizifo ezininzi ezinxulumene nobudala.Sinokuthi iiseli eziziincindi zingoyena nobangela wokwaluphala.
Emva koko indlela yokusombulula ezi zifo?Eyona ndlela ilula kukubulala ezi seli zencindi!Iiseli zeSenescent ziiseli ezinamafutha angasebenziyo aqokelelana ngobudala kuzo zonke izihlunu kunye namalungu omzimba wakho.I-Piperlongumine yenza i-apoptosis kwiiseli ze-senescent kwaye izibulale nge-ROS-independent mechanism.
I-Piperlongumine iyakwazi ukucothisa ukubunjwa kweeseli ze-senescent, ngokukhetha ukutshabalalisa iiseli ze-senescent kunye nokuvuselela impilo yakho.Isebenza kakuhle kunye nezinye izithako zokulwa nokuguga, ezifana ne-pterostilbene, i-resveratrol, i-fisetin, njl.
i-piperlongumine izilingo zeklinikhi
I-Piperlongumine ifundwe ngokubanzi kunyango lomhlaza olunyuka kwiimvavanyo zeklinikhi.Ukususela kwingxelo yokuqala enxulumene nokusetyenziswa kwayo kuphando lomhlaza (ngo-2011) malunga namaphepha angama-80 ashicilelwe kwiminyaka engaphantsi kwe-10, kodwa umsantsa usekho.Akukho zifundo zemetabolism ye-piperlongumine kumzimba womntu.
Iziphumo ebezingalindelekanga zePiperlongumine
Akukho ziphumo zibi zichaziweyo okwangoku.
