Naringenin 98%

I-Naringenin ine-skeleton structure ye-flavanone enezithathuamaqela e-hydroxykwi-4′, 5, kunye ne-7 carbons.Inokufumaneka zombini kwiiaglycoluhlobo, naringenin, okanye kuyoglycosidicifom,naringin, enodibaniso lwedisaccharide neohesperidosisiqhotyoshelwe nge-aglycosidicunxibelelwano kwi-carbon 7. Njengoninzi lwe-flavanones, i-naringenin ineziko le-chiral elilodwa kwi-carbon 2, ekhokelela ekubenienantiomericiifom zekhompawundi.I-enantiomers zifumaneka kwiireyishini ezahlukeneyo kwimithombo yendalo.Ubuhlangaye-S(-)-naringenin iboniswe ukuba yenzeke ngokukhawuleza.I-Naringenin ibonakaliswe ukuba iyaxhathisa kwi-enatiomerization ngaphezu kwe-pH 9-11.

Ukwahlula kunye nohlalutyo lwe-enantiomers luphononongwe ngaphezulu kweminyaka engama-20, ngokuyintloko ngokusebenzisaichromatography yolwelo olusebenza kakhulukwizigaba zokumiswa kwe-chiral ezenziwe nge-polysaccharide.Kukho ubungqina obucebisayostereospecific i-pharmacokineticskwayei-pharmacodynamicsiiprofayili, ezicetywayo ukuba zibe yingcaciso yoluhlu olubanzi kwi-bioactivity exeliweyo ye-naringenin.

I-Naringenin kunye ne-glycoside yayo ifunyenwe kwiindidi ezahlukeneyoimifunokwayeiziqhamo, kuqukai-grapefruit,i-bergamot, orenji omuncu, i-cherry emnandi, iitumato, ikoko,I-oregano yamaGrike, amanzi eminti,idrynariakunye nakwiiimbotyi.Umlinganiselo we-naringenin ukuya kwi-naringin uyahluka phakathi kwemithombo, njengoko kunjalo nangomlinganiselo we-enantiomeric.

Naringenin yeNdalo enyulu

CAS#:480-41-1

[Igama lesiNgesi]:Naringenin
[Inkcazo]: 98%
[Iipropati zeMveliso]:umgubo ongekho-mhlophe
[Indlela yovavanyo]: HPLC
[Ifomula]:C15H12O5
[CAS.NO]:480-41-1
[Ubunzima bemolekyuli]:272.25 g•mol−1
Indawo yokunyibilika kunye nokunyibilika:mp251°C,Inyibilika etywaleni, ether kunye nebenzene.phantse ayinyibiliki emanzini.

Igama lemveliso:Naringenin98%

Inkcazo:98% yi-HPLC

Igama lemveliso: Naringenin

Umthombo wezityalo: Citrus grandis(L.) Osbeck

I-CAS NO.480-41-1

Imbonakalo: Emhlophe okanye ngaphandle komgubo omhlophe

Isimo se-GMO:GMO Mahala

Ukupakisha: kwi-25kgs fiber drums

Ugcino: Gcina isikhongozeli singavulwanga kwindawo epholileyo neyomileyo, Zigcine kude nokukhanya okuqinileyo

Ubomi beShelf: iinyanga ezingama-24 ukusuka kumhla wokuvelisa

1. I-Naringenin ine-anticancer effect, inokubulala iiseli ezahlukeneyo zomhlaza.

2. I-Naringenin inefuthe elikhuselayo kwi-focal cerebral ischemia reperfusion kwiigundane, kwaye indlela yayo inokuhambelana nokutshabalalisa okusebenzayo kweeradicals zamahhala.I-Naringenin yehlise kakhulu umthamo wamanzi we-cerebral, yanciphisa umthamo we-cerebral infarction ye-hemisphere yobuchopho engasebenzi kakuhle, yehlisa inqanaba le-MDA kwaye yaphucula umsebenzi we-SOD engqondweni.Oku kubonisa ukuba iNaringenin inokuba nefuthe lokukhusela kwi-hemisphere yengqondo.

3. I-Naringenin inokunciphisa kakhulu i-cholesterol concentration ye-plasma kunye nomxholo we-cholesterol ye-hepatic.

4. I-Naringenin nayo ibonakaliswe ukunciphisa ukuveliswa kwentsholongwane ye-hepatitis C nge-hepatocytes (iiseli zesibindi) ezosulelekileyo.

inkcubeko yeseli .Oku kubonakala ngathi kukwesibini kwisakhono seNarigenin sokuthintela ukukhuselwa kwe-lipoprotein ephantsi kakhulu ngeeseli.

I-5.I-Naringenin inefuthe le-bioactive kwimpilo yabantu njenge-antioidant, i-scavenger yamahhala yamahhala, i-antisepsis, i-anti-inflammatory, i-antispasmodic activity.

Isicelo

1.Isifo sika-Alzheimer

I-Naringenin iphandwa njengonyango olunokubakho kwi-Alzheimer's Disease.I-Naringenin ibonakaliswe ukuphucula imemori kunye nokunciphisa iiprotheni ze-amyloid kunye ne-tau kwisifundo usebenzisa imodeli yemouse ye-Alzheimer's Disease.

2.I-antibacterial, antifungal, kunye ne-antiviral

Kukho ubungqina beempembelelo ze-antibacterial kwi-H. pylori.I-Naringenin nayo ibonakaliswe ukunciphisa ukuveliswa kwentsholongwane ye-hepatitis C nge-hepatocytes eyosulelekileyo (iiseli zesibindi) kwinkcubeko yeseli.Oku kubonakala kukwesibini kwisakhono se-naringenin sokuthintela ukukhuselwa kwe-lipoprotein ephantsi kakhulu ziiseli.Iziphumo ze-antiviral ze-naringenin okwangoku ziphantsi kophando lwezonyango.Iingxelo zeziphumo ze-antiviral kwi-polioviruses i-HSV-1 kunye ne-HSV-2 nazo zenziwe, nangona ukuphindaphinda kweentsholongwane akuzange kuthintelwe.

3. I-Antioxidant

I-Naringenin ibonakaliswe ukuba ineempawu ezibalulekileyo ze-antioxidant.

I-Naringenin nayo ibonakaliswe ukunciphisa umonakalo we-oxidative kwi-DNA in vitro kunye nezifundo zezilwanyana.