I-Hesperidin Methyl Chalcone98% by UV: Incazelo Yomkhiqizo Ephelele
1. Isingeniso se-Hesperidin Methyl Chalcone (HMC)
I-Hesperidin Methyl Chalcone (HMC) iwumphumela we-methylated we-hesperidin, i-flavonoid etholakala ngokwemvelo esithelweni esisawolintshi njengamawolintshi, ulamula, namagilebhisi. Ngokuhlanzeka okunqunywe yi-UV okungu-≥98%, le nhlanganisela yaziwa kabanzi ngezinzuzo zayo ezinezici eziningi empilweni yemithambo, ukunakekelwa kwesikhumba, nokuvikelwa kwe-antioxidant. Ifomula yayo yamangqamuzana ithi C29H36O15 (isisindo sengqamuzana: 624.59 g/mol), futhi ibonakala ngempushana ecwebezelayo ephuzi kuya kuwolintshi ene-hygroscopic futhi encibilika emanzini, ethanol, ne-methanol.
2. Imininingwane Yomkhiqizo
- Inombolo ye-CAS:24292-52-2
- Ubumsulwa: ≥98% ngokuhlaziywa kwe-UV
- Ukubukeka: Okuphuzi kuya ku-orange crystalline powder
- Ukunyibilika:Isitoreji: Gcina endaweni epholile, neyomile (2–8°C) kude nokukhanya kanye nomswakama. Impilo yeshelufu: iminyaka emi-2 .
- Incibilika ngokukhululeka emanzini, i-ethanol, ne-methanol.
- Incibilika kancane ku-ethyl acetate.
- Ukupakisha: 25 kg/drum (izikhwama ze-polyethylene ezinezingqimba ezimbili ngaphakathi kwemiphongolo yamakhadibhodi) .
3. Izinzuzo Eziyinhloko kanye Nezindlela Zokusebenza
3.1 Impilo ye-Vascular and Circulatory
I-HMC iqinisa ama-capillaries ngokunciphisa ukungakwazi ukungena futhi ithuthukise ithoni ye-venous, iyenze isebenze kahle ekwelapheni izimo ezifana nokuntuleka kwe-venous okungapheli, ama-hemorrhoids, kanye nemithambo ye-varicose. Izifundo zomtholampilo zigqamisa ukusebenzisana kwayo neI-Ruscus aculeatusukukhipha kanye ne-ascorbic acid, okuhlanganisa ukuthuthukisa i-microcirculation futhi kunciphise i-edema.
3.2 Izicelo Zokunakekelwa Kwesikhumba Nesikhumba
- I-Anti-Red and Dark Circle Reduction: I-HMC yehlisa ukuvuza kwe-capillary ngaphansi kwamehlo, yehlisa ukuguquguquka okuluhlaza okwesibhakabhaka kanye nokukhukhumala. Kuyisithako esibalulekile kumakhilimu wamehlo aphambili (isb,MD Skincare Phakamisa Khanyisa Eye Cream,I-Provectin Plus Advanced Eye Cream).
- Ukuvikelwa kwe-UV kanye Nokumelana Nokuguga: I-HMC inciphisa ukucindezeleka okwenziwe yi-UVB kwe-oxidative, ivimbela i-MMP-9 (i-enzyme eyonakalisa i-collagen), futhi ikhuthaze ukukhiqizwa kwe-filaggrin ukuze kuthuthukiswe umsebenzi wokuvinjelwa kwesikhumba.
- I-Anti-Inflammatory and Antioxidant Effects: Ngokucindezela izindlela ze-NF-κB ne-IL-6, i-HMC inciphisa ukuvuvukala nokulimala kwe-oxidative okuxhunywe kuma-acne, i-rosacea, ne-photoaging.
3.3 Umsebenzi we-Broad-Spectrum Antioxidant
I-HMC yenza kusebenze indlela yokusayina ye-Nrf2, ikhuphule ama-antioxidants angapheli njenge-glutathione ne-superoxide dismutase. Lo mshini uvikela emisebeni ye-UV, ukungcola, kanye nezingcindezi ze-metabolic.
4. Izicelo Kumafomula
4.1 I-Nutraceuticals
- Umthamo: 30-100 mg/ngosuku kumaphilisi noma amaphilisi okusekela i-venous.
- Amafomula Enhlanganisela: Avame ukubhangqwa nawoI-Diosmin,I-Ascorbic Acid, nomaI-Ruscus Extractukuze kuthuthukiswe i-bioavailability nokusebenza kahle .
4.2 Izimonyo Nezihloko
- Ukugxila: 0.5-3% kumaserum, okhilimu, namajeli .
- Amafomula Abalulekile:
- Ama-Serum Anti-Redness: Yehlisa i-erythema ebusweni nokuzwela.
- Imikhiqizo ye-Eye Contour: Iqondise imibuthano emnyama kanye nokukhukhumala (isb,I-Kool Eye Gelnge-menthol yemiphumela yokupholisa).
- Imikhiqizo Yokunakekela Ilanga: Isebenza njengesihlungi se-UV (izinga eliphezulu lokumunca ku-~284 nm) futhi lizinzisa i-Avobenzone kumakhilimu elanga .
5. Ukuqinisekisa Ikhwalithi Nokuphepha
- Ukuhlolwa Kobumsulwa: Kuthobelana namazinga ekhemisi kusetshenziswa i-HPLC kanye ne-IR spectroscopy.
- Iphrofayela Yokuphepha:Isimo Sokulawula: Ihlangabezana nemihlahlandlela ye-EU kanye ne-US FDA yezithako zokudla nezimonyo.
- Ukungacasuli ngemithamo enconyiwe (LD50> 2000 mg/kg kumagundane).
- Abukho ubuthi obubikiwe noma ubuthi bokuzala .
6. Izinzuzo Zemakethe
- I-Bioavailability Ephezulu: Ukumuncwa okuphakeme uma kuqhathaniswa ne-hesperidin yomdabu.
- Ukusebenza okuningi: Kukhuluma kokubili ukukhathazeka kwezempilo nobuhle (isb, impilo yemithambo + yokulwa nokuguga).
- Ukusekelwa Komtholampilo: Izifundo ezingaphezu kuka-20 ezibuyekezwe ontanga ziqinisekisa ukusebenza kahle kwayo ekuvikeleni imithambo, ukumelana ne-UV, nokulawula ukuvuvukala.
7. Uku-oda nokwenza ngokwezifiso
- I-MOQ: 25 kg/drum (ukupakishwa ngokwezifiso kuyatholakala).
- Amadokhumenti: I-COA, i-MSDS, kanye nedatha yokuzinza enikeziwe lapho ucelwa.
- Amasevisi e-OEM: Ukwakheka okuklanyelwe okokudla okunomsoco, izimonyo, noma ezemithi.
8. Isiphetho
I-Hesperidin Methyl Chalcone engu-98% nge-UV iyi-premium, isithako esisekelwa isayensi esinezinzuzo ezifakazelwe zobuqotho bemithambo, impilo yesikhumba, nokuvikela i-oxidative. Ukuguquguquka kwayo ekwenziweni—kusuka kokhilimu wamehlo kuya kwezithasiselo ze-venous—kuyenza ibe yisu lokukhetha kumabhrendi aqondise izimakethe ezikhathalela impilo nezigxile ebuhleni.
