Umhlahlandlela Womkhiqizo Ophelele:I-Kojic Acid Dipalmitate98% (HPLC) Yesikhumba Esimhlophe kanye Nokumelana Nokuguga
1. Isingeniso kuI-Kojic Acid Dipalmitate
I-Kojic AcidI-Dipalmitate (KAD, CAS79725-98-7) iwukuphuma oku-liposoluble kwe-kojic acid, edume ngokuzinza kwayo okuphakeme, ukusebenza ngempumelelo, nokuphepha ekwenziweni kwezimonyo. Njengesizukulwane esilandelayo se-tyrosinase inhibitor, yehlisa ngempumelelo ukwakheka kwe-melanin, ibhekana ne-hyperpigmentation, futhi ikhuthaze ithoni yesikhumba. Ngokuhlanzeka okungu-98% okuqinisekiswe yi-HPLC, lesi sithako silungele imikhiqizo yokunakekelwa kwesikhumba ephezulu eqondise amabala amnyama, i-melasma, nokushintsha kombala okuhlobene nobudala .
Izinhlelo zokusebenza ezibalulekile:
- Ukukhanya Kwesikhumba: Kunqanda ukukhiqizwa kwe-melanin ngokuvimbela umsebenzi we-tyrosinase, okudlula i-kojic acid yendabuko.
- I-Anti-Aging: Yehlisa imigqa emihle futhi ithuthukise ukunwebeka kwesikhumba ngokusebenzisa izakhiwo ze-antioxidant.
- Amafomula Emisebenzi Ehlukahlukene: Ihambisana namaserum, okhilimu, okokuvikela ilanga, nemikhiqizo elwa nezinduna .
2. Izakhiwo Zamakhemikhali Nezemvelo
I-Molecular Formula: C₃₈H₆₆O₆
Isisindo samangqamuzana: 618.93 g/mol
Ukubukeka: I-crystalline powder emhlophe ukuya kokumhlophe
Indawo Encibilikayo: 92–95°C
Ukunyibilika: Ukuncibilika kuwoyela (kuhambisana nama-esters, uwoyela wamaminerali, notshwala).
Izinzuzo zokuzinza:
- I-pH Range: Izinzile ku-pH 4–9, ilungele ukwakheka okuhlukahlukene .
- Ukumelana Nokushisa/Kokukhanya: Akukho oksijini noma ukushintsha kombala ngaphansi kokushisa noma ukuchayeka kwe-UV, ngokungafani ne-kojic acid.
- I-Metal Ion Resistance: Igwema i-chelation, iqinisekisa ukuqina kombala kwesikhathi eside .
3. Indlela Yokwenza
I-KAD isebenza ngomshini okabili:
- I-Tyrosinase Inhibition: Ivimba indawo ye-enzyme ye-catalytic, ivimbele ukwakheka kwe-melanin. Ucwaningo lubonisa ukusebenza ngempumelelo okuphezulu okungu-80% kune-kojic acid.
- Ukukhishwa Okulawulwayo: Ama-Esterases esikhumbeni enza i-hydrolyze i-KAD ibe yi-kojic acid esebenzayo, iqinisekisa ukubola okuhlala njalo .
Izinzuzo Zomtholampilo:
- Yehlisa amabala obudala, i-post-inflammatory hyperpigmentation (PIH), kanye ne-melasma.
- Ithuthukisa ukusebenza kwesikrini selanga ngokunciphisa i-melanogenesis ebangelwa yi-UV .
4. Izinzuzo OverI-Kojic Acid
| Ipharamitha | I-Kojic Acid | I-Kojic Acid Dipalmitate |
|---|---|---|
| Ukuzinza | I-oxidize kalula, iphenduka ibe phuzi | Ukushisa/ukukhanya okuzinzile, akukho ukushintsha kombala |
| Ukuncibilika | Ancibilikayo emanzini | Amafutha ancibilikayo, ukumunca kangcono kwesikhumba |
| Ingozi yokucasuka | Okumaphakathi (okuzwela i-pH) | Phansi (ithambile esikhumbeni esibucayi) |
| Ukuvumelana nezimo | Ilinganiselwe ku-pH ene-acidic | Ihambisana ne-pH 4–9 |
5. Iziqondiso Zokwakha
Umthamo onconyiwe: 1–5% (3–5% wokuhlanza okujulile) .
Ukufakwa kwesinyathelo ngesinyathelo:
- Ukulungiswa Kwesigaba Samafutha: Chaza i-KAD ku-isopropyl myristate/palmitate ku-80°C imizuzu emi-5.
- I-Emulsification: Hlanganisa isigaba samafutha nesigaba se-aqueous ku-70 ° C, i-homogenize imizuzu engu-10.
- Ukulungiswa kwe-pH: Gcina i-pH engu-4–7 ukuze uthole ukuzinza okuphelele.
Isampula Lefomula (I-Whitening Serum):
| Isithako | Iphesenti |
|---|---|
| I-Kojic Acid Dipalmitate | 3.0% |
| I-Niacinamide | 5.0% |
| I-Hyaluronic Acid | 2.0% |
| Vitamin E | 1.0% |
| Izilondolozi | qs |
6. Ukuphepha Nokuhambisana
- Okungeyona I-Carcinogenic: Izinhlangano ezilawulayo (EU, FDA, China CFDA) zigunyaza i-KAD ukusetshenziswa kwezimonyo. Ucwaningo luqinisekisa ukuthi ayikho ingozi ye-carcinogenic.
- Izitifiketi: ISO 9001, REACH, kanye nezinketho ze-Halal/Kosher ziyatholakala.
- I-Eco-Friendly: Kutholwe kwa-non-GMO, izinto zokusetshenziswa ezingenalo unya .
7. Ukupakisha kanye Logistics
Osayizi Abatholakalayo: 1 kg, 5 kg, 25 kg (ngezifiso)
Isitoreji: Indawo epholile, eyomile (<25°C), ivikelekile ekukhanyeni.
I-Global Shipping: I-DHL/FedEx yamasampula (izinsuku ezingu-3–7), impahla yasolwandle yama-oda amaningi (izinsuku ezingu-7–20) .
8. Kungani Khetha I-KAD Yethu 98% (HPLC)?
- Isiqinisekiso Sobumsulwa: 98% siqinisekiswe yi-HPLC, kuhlinzekwe i-COA ne-MSDS.
- Ukusekelwa kwe-R&D: Ukubonisana kwamahhala kwezobuchwepheshe kanye nokuhlolwa kwesampula.
- Ukuthola usizo Oluqhubekayo: Ukusebenzisana nabahlinzeki abaqinisekisiwe be-ECOCERT .
9. Imibuzo Evame Ukubuzwa
Q: Ingabe i-KAD iphephile kumathoni esikhumba amnyama?
A: Yebo. Iphrofayili yayo yokucasuka ephansi iyenza ifanelekele izinhlobo zesikhumba ze-Fitzpatrick IV–VI.
Umbuzo: Ingabe i-KAD ingakwazi ukufaka esikhundleni se-hydroquinone?
A: Nakanjani. I-KAD inikezela ngokusebenza ngokulinganayo ngaphandle kwe-cytotoxicity.
Amagama angukhiye: I-Kojic Acid Dipalmitate, I-Skin Whitening Agent, i-Tyrosinase Inhibitor, i-Melanin Reduction, i-Cosmetic Formulation Guide, Ukwelashwa Kwe-Hyperpigmentation, Isithako Esizinzile Sokumhlophe.
Incazelo: Zitholele isayensi ngemuva kwe-Kojic Acid Dipalmitate 98% (HPLC)—isicwebezeli sesikhumba esizinzile, esingacasuli. Funda amathiphu ayo okwakhiwa, indlela, kanye nedatha yokuphepha yezimakethe ze-EU/US.
