ʻO ka Adenosine he purine nucleoside i haku ʻia me kahi mole o ka adenine i hoʻopili ʻia i kahi mole mole kōpaʻa ribose (ribofuranose) ma o kahi paʻa β-N9-glycosidic.ʻIke nui ʻia ka Adenosine ma ke ʻano a he hana koʻikoʻi i nā kaʻina biochemical, e like me ka hoʻoili ʻana o ka ikehu - e like me adenosine triphosphate (ATP) a me adenosine diphosphate (ADP) - a me ka transduction hōʻailona e like me ka cyclic adenosine monophosphate (cAMP).He neuromodulator hoʻi ia, i manaʻoʻiʻo ʻia he kuleana i ka hoʻoikaika ʻana i ka hiamoe a me ke kāohi ʻana i ka hoʻāla.He kuleana hoʻi ʻo Adenosine i ka hoʻoponopono ʻana i ke kahe o ke koko i nā ʻāpana like ʻole ma o ka vasodilation.
Inoa mea kūʻai:Adenosine
Inoa ʻē aʻe:Adenine riboside
No CAS:58-61-7
Ke Kumu Molekala: C10H13N5O4
Kaumaha molekula: 267.24
EINECS NO.: 200-389-9
Ka helu hehee: 234-236ºC
Hōʻike: 99% ~ 102% na HPLC
Ke ʻano: ʻO ka pauka keʻokeʻo me ke ʻala a me ka ʻono
Kūlana GMO: ʻAʻole GMO
Hoʻopili: ma 25kgs fiber drums
Ka mālama ʻana: E mālama i ka pahu i wehe ʻole ʻia ma kahi maloʻo a maloʻo, e haʻalele i ka mālamalama ikaika
Ola Ola: 24 mahina mai ka lā i hana ʻia
Hana:
-ʻO Adenosine kahi nucleoside endogenous i loko o nā pūnaewele kanaka i loko o ka myocardium ma o ka phosphorylation e hoʻohua ai i ka adenylate i komo i ka metabolism ikehu myocardial.Hele pū ʻo Adenosine i ka hoʻonui ʻana o nā moku coronary, e hoʻonui ana i ke kahe koko.
– He hana physiological ka Adenosine i ka ʻōnaehana cardiovascular a me nā ʻōnaehana a me nā hui o ke kino.Hoʻohana ʻia ʻo Adenosine i ka synthesis adenosine triphosphate, adenosine (ATP), adenine, adenosine, nā mea koʻikoʻi vidarabine.
Mechanism
He kuleana koʻikoʻi ka Adenosine i ka biochemistry, me ka adenosine triphosphate (ATP) a i ʻole adeno-bisphosphate (ADP) ʻano o ka hoʻololi ʻana o ka ikehu, a i ʻole i ka cyclic adenosine monophosphate (cAMP) no ka hoʻouna ʻana i ka hōʻailona a pēlā aku.Eia kekahi, ʻo ka adenosine kahi neurotransmitter inhibitory (inhibitory neurotransmitter), hiki ke hāpai i ka hiamoe.
ʻImi Hoʻonaʻauao
I ka lā 23 Kekemapa "kūlohelohe - Lapaʻau" (Nature Medicine), hōʻike ʻia kahi noiʻi hou e kōkua ka hui iā mākou e hoʻohaʻahaʻa i ka lolo o ka hiamoe a me nā maʻi lolo ʻē aʻe ʻo Parkinson's maʻi ʻO ka hoʻoulu ʻana i ka lolo hohonu o ka holomua he mea koʻikoʻi.Hōʻike kēia haʻawina: hiki i ka lolo hiamoe ke alakaʻi i ka hui - ʻo Adenosine kahi hopena hoʻoulu lolo hohonu (DBS) o ke kī.ʻO ka ʻenehana no ka mālama ʻana i ka maʻi o Parkinson a me nā maʻi me ka haʻalulu nui, ua hoʻāʻo ʻia kēia ʻano no ka mālama ʻana i ke kaumaha nui.
