keʻokeʻo peony extract

Inoa mea kūʻai:Wehe Peony Keʻokeʻopauda

inoa ʻē aʻe:Pākē Pula Keʻokeʻo Pākē pauda

Puna Botanical:Radix Paeoniae Alba

Nā mea komo:Ka huina glucosides o Paeonia (TGP):Paeoniflorin, Oxypaeoniflorin, Albiflorin, Benzoylpaeoniflorin

Nā kikoʻī:Paeoniflorin10%~40% (HPLC), 1.5%Albasides, 80%ʻO Glycosides

Helu CAS:23180-57-6

Kala: Melemele-ʻulaʻulapaudame ke ʻala ʻano a me ka ʻono

GMOKūlana: GMO Free

Hoʻopili: ma 25kgs fiber drums

Ka mālama ʻana: E mālama i ka pahu i wehe ʻole ʻia ma kahi maloʻo a maloʻo, e haʻalele i ka mālamalama ikaika

Ola Ola: 24 mahina mai ka lā i hana ʻia

Wehe Peony Keʻokeʻoe pili ana i ka unuhi ʻana o nā mea hana mai ka peony keʻokeʻo e nā ʻano ʻepekema e like me kahi ʻenehana kūʻokoʻa.Wahi a ka loiloi a ka poʻe akamai, ʻo nā mea hana o ka peony keʻokeʻo extract no ke kino kanaka e like me ka pakuhi.ʻEhā o nā mea nui loa ʻo Paeoniflorin, Oxypaeoniflorin, Albiflorin, a me Benzoylpaeoniflorin.

Lawe ʻia ka peony keʻokeʻo mai ke aʻa maloʻo o Paeonia lactiflora Pall., kahi mea kanu o ka ʻohana Ranunculaceae.ʻO kāna mea nui he paeoniflorin, hiki ke hoʻohana nui ʻia ʻaʻole wale i ka lāʻau lapaʻau akā i ka ʻoihana hoʻonaninani.ʻO ka peony keʻokeʻo he mea hoʻopiʻi hana PDE4 maikaʻi loa.Ma ke kāohi ʻana i ka hana PDE4, hiki iā ia ke hana i ka cAMP o nā ʻano mea ʻeha a me nā ʻāpana pale (e like me neutrophils, macrophages, T lymphocytes a me eosinophils, a me nā mea ʻē aʻe).Loaʻa iā ia ka analgesic, antispasmodic, anti-ulcer, vasodilator, hoʻonui i ke kahe koko o ke kino, antibacterial, pale-paʻa, detoxifying, anti-mutagenic, a me nā hopena anti-tumor.

ʻO 1,2,3,6-tetragalloyl glucose, 1,2,3,4,6-pentagalloyl glucose a me ka hexagalloyl glucose a me ka heptagalloyl glucose i hoʻokaʻawaleʻia mai ka tannin o ke aʻa peony keʻokeʻo.Loaʻa iā ia ka dextrorotatory catechin a me ka ʻaila volatile.ʻO ka aila volatile ka nui o ka benzoic acid, peony phenol a me nā mea ʻona a me nā phenols ʻē aʻe.1. Paeoniflorin: molecular formula C23H28O11, molecular weight 480.45.ʻO ka pauka amorphous hygroscopic, [α]D16-12.8° (C=4.6, methanol), ʻo ka tetraacetate he mau kristal nila kala ʻole, mp.196℃.2. Paeonol: ʻO nā inoa like ʻole he paeonol, peony alcohol, paeonal, a me peonol.ʻO ke kumu molekala C9H10O3, ke kaumaha molekala 166.7.Hiki ke hoʻoheheʻe ʻia me ka ethanol, etera, acetone, chloroform, benzene a me carbon disulfide nā ʻano kristal like ʻole o ka nilala (ethanol), mp.50℃, hiki ke hoʻoheheʻe ʻia i ka wai.3. Nā mea'ē aʻe: Loaʻa i kahi oxypaeoniflorin liʻiliʻi, albiforin, benzoylpaeoniflorin, lactiflorin, kahi paeoniflorigenone monoterpene hou me ka hopena neuromuscular blocking ma nāʻiole, 1,2,3,4,6-Pentagalloylglucose me ka hopena antiviral, gallotannin, d-catechin, gallic. ʻakika, ethyl gallate, tannin, β-sitosterol, kō, starch, mucus, etc.

Nā hana:

1. Nā hopena anti-inflammatory, antibacterial a me antiviral.ʻO ka peony keʻokeʻo he mea nui ka hopena i ka hua manu keʻokeʻo acute inflammatory edema i nā ʻiole a keʻakeʻa i ka hoʻonui ʻana o ka granuloma pulupulu.Loaʻa i nā glycosides o paeony nā hopena anti-inflammatory a pili kino i ka immunomodulatory ma nā ʻiole me ka adjuvant arthritis.ʻO ka hoʻomākaukau ʻana i ka peony keʻokeʻo he mau hopena inhibitory ma Staphylococcus aureus, hemolytic Streptococcus, pneumococcus, Shigella dysenteriae, Typhoid bacillus, Vibrio cholerae, Escherichia coli a me Pseudomonas aeruginosa.Eia kekahi, hiki i ka decoction peony 1:40 ke kāohi iā Jingke 68-1 virus a me ka maʻi herpes.
2. Hepatoprotective hopena.He hopena koʻikoʻi ko ka peony keʻokeʻo i ka pōʻino o ka ate a me ka piʻi ʻana o ka SGPT ma muli o D-galactosamine.Hiki iā ia ke hōʻemi i ka SGPT a hoʻihoʻi i nā ʻeha o ka ate a me ka necrosis i ka maʻamau.Hiki i ka ethanol extract o ke aʻa peony keʻokeʻo ke hoʻemi i ka piʻi ʻana o ka hana holoʻokoʻa o ka lactate dehydrogenase a me nā isoenzymes i nā ʻiole me ka ʻeha ʻeha o ka ate ma muli o ka aflatoxin.Hiki i nā glycosides o paeony ke pale i ka piʻi ʻana o ka SGPT a me ka lactate dehydrogenase i nā ʻiole i hana ʻia e ka carbon tetrachloride, a he hopena antagonistic i ka degeneration eosinophilic a me ka necrosis o ka ʻiʻo ate.
3. ʻO ka hopena Antioxidant: ʻO ke aʻa peony keʻokeʻo TGP loaʻa nā hopena antioxidant a me nā cell membrane stabilizing hopena, a he hopena scavenging paha i nā radical manuahi.
4. Hiki ke hoʻonui i nā kīʻaha koko coronary o ka puʻuwai kaʻawale, pale i ka ischemia myocardial acute i nā ʻiole i hoʻokumu ʻia e ka pituitaryin, a hoʻemi i ka pale ʻana o nā kīʻaha peripheral a hoʻonui i ke kahe koko ke hoʻokomo ʻia i loko o ke aʻa.He hopena hoʻi ko Paeoniflorin ma luna o nā kīʻaha koko coronary a me nā kīʻaha koko peripheral, a hoʻemi i ke kahe koko.Ua hōʻike ʻia nā haʻawina ʻo ka paeoniflorin, kahi ʻāpana o ke aʻa peony keʻokeʻo, he hopena pale i ka ADP-induced platelet aggregation i nā ʻiole in vitro.
5. ʻO ka hopena o ka ʻōpū o ka peony keʻokeʻo he hopena paʻa i ka ʻokiʻoki ʻana o ka hyperexcitability o ka ʻōpū a me ka ʻoki ʻana i hoʻokumu ʻia e ka barium chloride, akā ʻaʻohe hopena i ka contraction i hana ʻia e ka acetylcholine.ʻO ka hui ʻana o ka licorice a me ke aʻa peony keʻokeʻo (0.21g) i hoʻokaʻawale ʻia i ka wai, he hopena koʻikoʻi koʻikoʻi i ka neʻe ʻana o ka ʻiʻo maʻemaʻe o ka ʻōpū i loko o nā rabbit in vivo.ʻOi aku ka maikaʻi o ka hopena i hui pū ʻia ma mua o kēlā me kēia, a ʻoi aku ka ikaika o ka hopena hoʻohaʻahaʻa pinepine ma mua o ka hopena hoʻemi amplitude.ʻO ka ho'ēmiʻana i ka pinepine o ka'ōpū o ka'ōpū rabbit 20 a 25 mau minuke ma hope o ka hoʻoponoponoʻana he 64.71% a me 70.59% o kēlā i loko o ka pūʻulu hoʻomalu maʻamau, aʻoi aku ka ikaika ma mua o ka atropine (0.25 mg) i ka pūʻulu hoʻomalu maikaʻi.Loaʻa i ka Paeoniflorin nā hopena pale i nā paipu ʻōpū kaʻawale a i loko o ka vivo gastric motility i loko o nā puaʻa puaʻa a me nā ʻiole, a me ka ʻiʻo ʻāʻī ʻāʻī o ka ʻiole, a hiki ke hoʻohālikelike i nā ʻokiʻoki i hana ʻia e ka oxytocin.Loaʻa iā ia kahi hopena synergistic me Chemicalbook alcohol extract FM100 o ka licorice.He hopena pale koʻikoʻi ko Paeoniflorin i nā maʻi ʻeha o ka ʻōpū i nā ʻiole i hoʻoulu ʻia e nā hoʻoulu koʻikoʻi.
6. ʻO nā hopena sedative, analgesic, a me nā hopena anticonvulsant.Loaʻa nā hopena sedative a me nā hopena analgesic keʻokeʻo peony injection a me paeoniflorin.ʻO ka hoʻokomo ʻana i kahi paeoniflorin liʻiliʻi i loko o ka lolo o nā holoholona hiki ke hoʻoulu i kahi kūlana hiamoe.Intraperitoneal injection o 1g/kg o paeoniflorin mai ke keʻokeʻo peony aʻa extract i loko o ka iole hiki ke hoemi i na holoholona 'hana kuʻuna, hooloihi i ka hiamoe manawa o ka pentobarbital, inhibit i ka writhing hopena o ka iole ma muli o ka intraperitoneal injection o ka acetic acid, a pale i ka pentylenetetrazole.Hoʻopuʻi ʻia.Loaʻa nā hopena analgesic nui o nā glycosides o paeony a hiki ke hoʻonui i nā hopena analgesic o morphine a me clonidine.ʻAʻole pili ka Naloxone i ka hopena analgesic o ka nui o nā glycosides o paeony, e manaʻo ana ʻaʻole kāna kumu analgesic e hoʻoulu i nā mea hoʻokipa opioid.Hiki i ka peony extract ke pale i ka convulsions i hoʻokumu ʻia e strychnine.ʻAʻohe hopena o Paeoniflorin i ka ʻiʻo iwi iwi kaʻawale, no laila ua manaʻo ʻia ʻo ia ka hopena anticonvulsant i ke kikowaena.
7. Ka hopena ma ka ʻōnaehana koko: Hiki i ka waiʻona Paeony ke kaohi i ka hōʻuluʻulu platelet i loko o nā lākeke i hoʻoulu ʻia e ADP, collagen, a me ka waika arachidonic in vitro.
8. Ka hopena ma ka ʻōnaehana pale.Hiki i ke aʻa peony keʻokeʻo ke hoʻoikaika i ka hana ʻana i nā antibodies cell spleen a hoʻoikaika i ka pane hoʻomākeʻaka o nā ʻiole i nā ʻiole ʻulaʻula hipa.Hiki i ka decoction peony keʻokeʻo ke kū'ē i ka hopena inhibitory o ka cyclophosphamide ma ke koko peripheral T lymphocytes i nā ʻiole, hoʻihoʻi iā lākou i nā pae maʻamau, a hoʻihoʻi i ka hana haʻahaʻa haʻahaʻa haʻahaʻa.Hiki i ka nui o nā glycosides o paeony ke hoʻoikaika i ka hoʻonui ʻana o nā lymphocytes splenic i nā ʻiole i hoʻoiho ʻia e concanavalin, e hoʻoikaika i ka hana ʻana o ka α-interferon i loko o nā leukocytes koko kaula kanaka i hoʻoulu ʻia e Newcastle chicken plague virus, a loaʻa ka hopena bidirectional i ka hana ʻana o ka interleukin-2 i ka ʻiole nā splenocytes i hoʻokomo ʻia e concanavalin.hopena hoʻoponopono.
9. Ka hopena ikaika: Hiki ke hoʻolōʻihi i ka manawa ʻauʻau o ka ʻiole keʻokeʻo peony waiʻona a me ka hypoxic ola manawa o nā ʻiole, a he hopena hoʻoikaika.
10. Nā hopena anti-mutagenic a me anti-tumor Hiki ke hoʻopilikia i ka hana enzyme o ka hui S9, a hiki ke hoʻopau i nā metabolites o benzopyrene a keʻakeʻa i kona hopena mutagenic.

11. Nā hopena ʻē aʻe (1) Ka hopena antipyretic: He hopena antipyretic ko Paeoniflorin i nā ʻiole me ke kuni kūlohelohe a hiki ke hoʻemi i ka mahana kino maʻamau o nā ʻiole.(2) Hoʻonui i ka hoʻomanaʻo: Hiki i nā glycosides o paeony ke hoʻomaikaʻi i ka maikaʻi ʻole o ka aʻo ʻana a me ka loaʻa ʻana o ka hoʻomanaʻo i nā ʻiole i hana ʻia e ka scopolamine.(3) Ka hopena anti-hypoxic: Hiki i nā glycosides o ka paeony keʻokeʻo ke hoʻolōʻihi i ka manawa ola o nā ʻiole ma lalo o ke kaomi maʻamau a me ka hypoxia, e hoʻemi i ka pau ʻana o ka oxygen holoʻokoʻa o nā ʻiole, a hoʻemi i ka make ʻana o nā ʻiole ma muli o ka make ʻana o ka potassium cyanide a me ka hypoxia.