Khoom npe:Dub Ginger Extract
Botanic Source: Kaempferia parviflora.L
CASNib: 21392-57-4
Lwm Lub Npe:5.7-Dimethoxyflavone
Specifications: 5.7-Dimethoxyflavone ≥2.5%
Tag nrho Flavonoids ≥10%
Xim:Ntshavhmoov nrog cov yam ntxwv tsw thiab saj
GMOStatus: GMO Dawb
Ntim: hauv 25kgs fiber ntau nruas
Cia: Khaws lub thawv tsis qhib hauv qhov chaw txias, qhuav, Khaws kom deb ntawm lub teeb muaj zog
Lub neej txee: 24 lub hlis txij li hnub tsim khoom
5,7-Dimethoxyflavone yog ib qho ntawm cov khoom tseem ceeb ntawm Kaempferia parviflora, uas muaj kev tiv thaiv kev rog, tiv thaiv kab mob, thiab tiv thaiv qog.5,7-Dimethoxyflavone inhibits cytochrome P450 (CYP) 3As.5,7-Dimethoxyflavone kuj yog ib qho tshuaj tiv thaiv qog nqaij hlav cancer mis (BCRP) inhibitor.
Hauv Vitro Kev Ua Haujlwm:
Qhov zoo tshaj plaws hauv vitro trypanocidal kev ua haujlwm rau T. brucei rhodesiense tau tawm los ntawm 7,8-dihydroxyflavone (50% inhibitory concentration [IC50], 68 ng / ml), ua raws li 3-hydroxyflavone, rhamnetin, thiab 7,8,3′, 4'-tetrahydroxyflavone (IC50s, 0.5 microg / ml) thiab catechol (IC50, 0.8 microg / ml).
Hauv Vivo Kev Ua Haujlwm:
5,7-Dimethoxyflavone (10 mg / kg, qhov ncauj, ib zaug ib hnub, rau 10 hnub) tuaj yeem txo qhov kev qhia ntawm CYP3A11 thiab CYP3A25 proteins hauv daim siab ntawm nas [1].
5,7-Dimethoxyflavone (25 thiab 50 mg / kg, qhov ncauj) tuaj yeem cuam tshuam sarcopenia hauv cov nas laus [3].
5,7-Dimethoxyflavone (50 mg / kg / d, qhov ncauj, kav ntev li 6 lub lis piam) tuaj yeem txo qhov hnyav nce thiab tiv thaiv lub siab rog hauv HFD nas [5].
MCE tsis tau lees paub qhov tseeb ntawm cov txheej txheem no.Lawv yog rau siv xwb.
